Turmeric oil is one of the primary components of turmeric, a perennial herb coming from the Zingiberaceae family. Turmeric oil has anti-oxidation, anti-cancer, anti-inflammatory, antibacterial, and cough-relieving functions. The primary components of turmeric oil are mostly sesquiterpenoids and also contain a large amount of phenolic materials. Turmeric extract has 3-5% turmeric oil, as well as turmeric oil contains 50% turmeric ketones. As an essential oil, turmeric ketones have effective skin obstacle repair work and also conditioning features, and also have the ability to enhance biological tasks. Turmeric extract assists to drain pipes pollutants in the blood and also skin, get rid of acne breakouts, safeguard the skin from damages, and make the skin pure and also stunning.
The antioxidant and anti-inflammatory effects of turmeric oil generally increase antioxidant defense by quenching free radicals or inhibit the release of pro-inflammatory mediators. Correlation of anti-inflammatory and antioxidant activity of vanilla root essential oil, associated with reduction of superoxide and malondialdehyde levels by its lipopolysaccharide. Essential oils can significantly regulate gene expression and alter signal transduction pathways, affecting signal transduction in inflammation and antioxidant processes. The anti-inflammatory, analgesic and antioxidant properties of turmeric oil are mainly attributed to its main constituents and their synergistic effects.
The traditional Chinese medicine turmeric has a good antiviral effect. Within a certain concentration range, turmeric oil can significantly enhance cell proliferation, indicating that within a certain concentration range, low-concentration turmeric oil can promote cell growth. Turmeric oil also has obvious anti-porcine parvovirus effect, its inhibitory effect is higher than its blocking effect, its inhibitory effect and blocking effect are obviously better than direct killing effect, and its inhibitory effect and blocking effect are better than ribavirin , the direct killing effect of both was not obvious. The reason may be that after the active ingredient of turmeric oil enters the cells, it blocks a certain link of parvovirus replication, affects the expression of a certain gene in the cells, inhibits the proliferation of the virus, and thus exerts an antiviral effect; but its direct killing effect is not obvious The reason is that the parvovirus itself is an autonomous intranuclear replicating virus, which has strong resistance to the outside world, and drugs cannot exert obvious inhibitory effects outside the cells.
1. Effect of turmeric oil on ear swelling induced by xylene in mice
Xylene-induced mouse ear swelling was observed in each group. Oral administration of indomethacin significantly inhibited xylene-induced ear swelling in mice (P<0.01), and the inflammation inhibition rate reached 51.02%, which was equivalent to the inhibition rate of mice in the middle dose group. The mice in the high-dose group had the most obvious inhibitory effect on the swelling caused by xylene, and could significantly reduce the swelling of the right ear of the mice in the experimental group, with the highest inhibition rate being 91.84%.
2. Effect of turmeric oil on mouse toe swelling and inflammatory transmitters in tissue
Indomethacin, turmeric oil low, medium, and high dose groups all had significant inhibitory effects on the toe swelling of mice (P<0.05, P<0.01), and the positive control group and turmeric oil high dose group had significant inhibitory effects on the toe swelling of mice. The mouse toe swelling degree has a very significant inhibitory effect (P<0.01), and the inhibition rate of the toe swelling is 67.51% and 65.02% respectively. The relative content of PGE2 in the toes of mice fed with turmeric oil was significantly reduced, and it was proportional to the dose of turmeric oil. higher than that of non-inflammatory feet.
3. Effect of turmeric oil on mice writhing induced by glacial acetic acid
Each dose group of turmeric oil has obvious inhibitory effect on the writhing of mice, which can increase the pain threshold of mice, prolong the latency time of mice responding to pain stimuli, and reduce the number of writhing times caused by pain stimuli. Among them, the turmeric oil in the medium and high dose groups had a very significant inhibitory effect on the inhibition of writhing in mice (P<0.01). The improvement rate of mice in the high-dose group was 62.71%, which was equivalent to that of the positive control group.
4. Analgesic effect of turmeric oil on heat stimulation pain
There was no significant difference between the basic pain threshold of the mice in the blank control group and those of other dose groups (P>0.05). Compared with the blank control group, the paw-licking reaction time of the mice in the positive control group and the high-dose turmeric oil group was significantly prolonged after continuous administration for 5 days, and the pain threshold of the mice was increased in a time-dependent manner.
5. Scavenging ability of turmeric oil on DPPH free radicals
The scavenging rate of 7 kinds of samples to DPPH free radicals all increased with the increase of sample mass concentration. Among them, BHT has the highest clearance rate, and turmeric oil has the lowest clearance rate. However, the DPPH free radical scavenging rate of turmeric yogurt and VE gastrointestinal digestive juice at 50 mg/mL was similar to that of VC, which were 89.73% and 88.76%, respectively. After turmeric oil is digested by gastrointestinal juice, the scavenging ability of DPPH free radicals is improved, and the effect of turmeric oil gastric digestive juice is better than that of turmeric oil gastrointestinal digestive juice.
6. Total antioxidant capacity of turmeric oil
The total antioxidant capacity of 7 samples increased with the increase of mass concentration. Among them, the order of total antioxidant activity was VC>BHT>turmeric oil gastrointestinal digestive juice>turmeric oil>turmeric turmeric digestive juice>VE gastrointestinal digestive juice>VE gastric digestive juice. The total antioxidant activity of turmeric oil after digestion was higher than that of VE after digestion, and the effect of digestion by intestinal juice was better than that by gastric juice.
7. Scavenging effect of turmeric oil on O2−·
The ability of 7 samples to scavenge O2−· increases with the increase of sample mass concentration. When the mass concentration was 50 mg/mL, the clearance rate of VE gastrointestinal digestive juice was the best, with a clearance rate of 75.98%, and the clearance rate of turmeric oil was the lowest, 28.30%.
8. Antioxidative activity of turmeric oil on edible oil
Turmeric oil has antioxidant effect on soybean oil, and the antioxidant capacity of turmeric oil on soybean oil in the first 11 days has a certain dose-effect relationship. The capacity is improved, and the antioxidant effect on soybean oil is enhanced. However, when the amount of turmeric oil added increased to 1.00%, the antioxidant activity of soybean oil decreased accordingly. Among them, in the first 11 days, BHT had the highest antioxidant activity on soybean oil, and the effect of 0.60% turmeric oil was similar to that of VE. In addition, the induction period of the blank control treatment is relatively short, while the induction period of other treatments is relatively long, which further shows that turmeric essential oil has an antioxidant effect. But after 11 days, except for BHT, VE and 0.6% turmeric oil, the peroxide values of other samples showed a decreasing trend.
The half-maximum effective mass concentration (EC50) of the total antioxidant capacity of turmeric oil was 0.750 mg/mL, and the scavenging effect on O2−· was the worst. BHT has the strongest scavenging effect on DPPH free radicals (EC50 is 5.320 mg/mL); VE gastric juice has the strongest scavenging effect on O2−· (EC50 is 8.500 mg/mL), followed by turmeric oil gastric juice (EC50 is 8.680 mg /mL).
1. Relieve depression and anxiety
Turmeric essential oil is considered a powerful relaxant and balancer, and research shows it can help fight two extremely common mood disorders, depression and anxiety. As an effective essential oil for anxiety and depression, it improves mood and positive emotions. A randomized, double-blind, placebo-controlled study of 56 patients with major depressive disorder was published in the Journal of Affective Disorders in 2014. The findings showed that supplementation with BCM-95 curcumin was not only successful in reducing overall symptoms of depression, but also had anti-anxiety effects when taken for 8 weeks. BCM-95 Curcumin is a synergistic product of turmeric essential oil and curcumin without synthetic additives.
Another recent study, published in 2018, looked at the effects of BCM-95 curcumin and saffron on 123 patients with major depressive disorder. Overall, this randomized, double-blind, placebo-controlled study found that patients were treated with a low dose (250 mg) of BCM-95 twice daily. Curcumin, high-dose (500 mg) BCM-95, or combined low-dose (15 mg) curcumin and saffron for 12 weeks were effective in reducing symptoms of depression and anxiety in depressed patients.
2. Improve cold
The anti-inflammatory and anti-microbial capabilities of turmeric oil can really help with the stuffy nose that often accompanies the common cold. Simply add a few drops of turmeric oil to a diffuser or bowl of hot water and inhale the steam for quick relief from nasal congestion. Sniffing turmeric essential oil can also help ward off the bacteria that cause your cold in the first place.
3. Promote skin health
Is turmeric oil good for the face? Absolutely! So what are the benefits of turmeric for the skin? Many people use turmeric oil to lighten their skin, and it’s a good idea because topical use of turmeric has been shown to reduce facial hyperpigmentation and the appearance of fine lines and wrinkles. It can also be helpful as a natural acne treatment due to its anti-inflammatory and antibacterial properties. Just remember that you want to use a small amount of diluted turmeric oil to avoid temporarily staining the skin yellow.