Zhishang Chemical

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Zhishang Chemical

Pure Luteolin CAS 491-70-3

Molecular Formula: C15H10O6

Formula Weight: 286.24

ZSpharmac: Pure Luteolin Supplier

Product Name: Pure Luteolin
CAS No: 491-70-3
Purity: 99%

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Basic Info

Product Name:Pure Luteolin
Other Names:Luteolin
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Yellow Powder
EINECS No.:207-741-0
Provide:Pure Luteolin MSDS;
Pure Luteolin COA

What is Pure Luteolin?

Pure Luteolin is a very representative natural flavonoid, which belongs to weakly acidic tetrahydroxyflavonoids. It is widely distributed in the plant kingdom. In vegetables such as cabbage, cabbage, cauliflower, beet, broccoli, and carrots, and in the form of glycosides in celery, green peppers, perilla leaves, and fruit shells of Arachishypogaea, Ajugadecumbus, honeysuckle Among various plants such as Lonicera japonica Thunb, Gentianopsis spaludosa, and Valeriana amurensis Smir. Pure Luteolin is a yellow crystalline powder.

Pure Luteolin Property

Melting point ~330 °C(lit.)
Boiling point 348.61°C (rough estimate)
density 1.2981 (rough estimate)
refractive index 1.4413 (estimate)
storage temp. 2-8°C
solubility Methanol (Slightly, Heated)
form powder
color yellow
Water Solubility Soluble in aqueous alkaline solutions (1.4 mg/ml), ethanol (~5 mg/ml), dimethyl sulfoxide (7 mg/ml), 1eq. Sodium hydroxide (5 mM), dimethylformamide (~20 mg/ml), water (1 mg/ml) at 25°C and methanol.


Pharmacological Effects of Pure Luteolin

1. Anti-tumor: The repressive result of Pure Luteolin on the expansion of growth cells is generally through preventing the task of certain kinases in cells and obstructing the cell cycle.
2. Anti-oxidation: The anti-oxidation impact of Pure Luteolin is mostly shown up in its own oxidation reaction as a minimizing representative, which increases the activity of the antioxidant system of the microbe.
3. Anti-inflammation: The anti-inflammatory job of Pure Luteolin is largely emerged in its capability to decrease the task of inflammatory variable transcriptional regulatory authorities in addition to reduce the manufacturing of pro-inflammatory cytokines as well as inflammatory conciliators.
4. Neuroprotective outcome: Pure Luteolin has a security outcome on the understanding and likewise memory capability of the nerves.
5. Anti-fibrosis: Pure Luteolin can lower the level of liver fibrosis, lower the web content of hydroxyproline (HYP), malondialdehyde (MDA) in liver cells in addition to the expression of type I procollagen mRNA, and can prevent liver stellate in vitro Cellular (HSC) expansion as well as collagen synthesis. It can also improve the histopathological changes of lung fibrosis prompted by bleomycin, lower the lung weight index, substantially minimize the rise of MDA and HYP, along with inhibit the expression of changing growth factor-β1 (TGF-β1) mRNA in lung cells, artificial insemination can impede the spreading of human embryonic lung fibroblasts as well as advertise their apoptosis.
6. Anti-fertility as well as hormone results: Pure Luteolin has considerable dose-dependent anti-implantation activity. After dental administration, it can considerably increase the weight, size, thickness of the endometrium and also the height of its epithelial cells. It has estrogen-like outcomes when made use of alone. Hormonal effects, however when incorporated with ethinyl estradiol, it has in fact been revealed to have anti-estrogenic impacts.
7. Others: Pure Luteolin can prevent a series of bacteria as well as infections, such as Staphylococcus aureus, Escherichia coli, herpes simplex infection, polio infection, Coxsackie B3 infection, etc. It can hinder the task of HIV-1 integrase, as well as also has prospective anti-HIV impact. Luteolin can bind to the S2 healthy protein of extreme intense respiratory system condition (SARS) coronavirus, consequently impeding the infection from entering into host cells. Luteolin likewise has the result of standing up to Leishmania donovani, preventing the advancement of Leishmania donovani by preventing the activity of topoisomerase along with topoisomerase. In addition, luteolin similarly has the impact of immune guideline and also more.

Extraction Process of Pure Luteolin

About That Product:
If you need Pure Luteolin as a cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced Pure Luteolin manufacturer and supplier, ZSpharmac will provide Pure Luteolin raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Pure Luteolin Quotation