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Zhishang Chemical

Vitamin E Acetate Adalah CAS 58-95-7

Molecular Formula: C31H52O3

Formula Weight: 472.74

ZSpharmac: Vitamin E Acetate Adalah Supplement

Product Name: Vitamin E Acetate Adalah
CAS No: 58-95-7
Purity: 99%

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Basic Info

Product Name:Vitamin E Acetate Adalah
Other Names:D-alpha-Tocopheryl Acetate
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Yellow Oil or Semi-Solid
EINECS No.:200-405-4
Storage:Room Temp
Provide:Vitamin E Acetate Adalah MSDS;
Vitamin E Acetate Adalah COA

What is Vitamin E Acetate Adalah?

Vitamin E Acetate Adalah has 4 congeners referred to as alpha-tocopherol, beta-tocopherol, gamma-tocopherol, as well as delta-tocopherol. They all have the commonness of all-natural VE, as well as reveal different individualities, so they are distinguished in function and also applicable areas. The α-type monomer has the best biological task as well as has the most effective effectiveness when utilized as medication and also health care items.

Vitamin E Acetate Adalah has the impact of anti-aging, improving immunity, as well as has an adjuvant therapy effect on cardiovascular and cerebrovascular conditions. It has actually been extensively utilized in the pharmaceutical market, health care item market, food sector, and cosmetics industry. The most important commercialized kind of Vitamin E Acetate Adalah is Vitamin E Acetate Adalah (normally described as α-tocopherol acetate). Condensation of the by-products yields tocopherol, which is then esterified with acetic anhydride to yield vitamin E acetate.

Vitamin E Acetate Adalah Property

Melting point ~25 °C(lit.)
alpha 3 º (c=2, in ethanol 25 ºC)
Boiling point 224 °C0.3 mm Hg(lit.)
density 0.953 g/mL at 25 °C(lit.)
refractive index n20/D 1.496(lit.)
Fp >230 °F
storage temp. room temp
solubility Practically insoluble in water, freely soluble in acetone, in anhydrous ethanol and in fatty oils, soluble in ethanol (96 per cent).
form oil or semi-solid
color yellow
Water Solubility <0.1 g/100 mL at 17 ºC


Vitamin E Acetate Adalah Uses

  1. Vitamin E Acetate Adalah is an usual vitamin supplement. It is an ester of acetic acid and likewise tocopherol (vitamin E) and also is typically made use of in skin treatment items such as skin lotions. Tocopheryl acetate is not oxidized as well as also can travel through the skin into living cells, where roughly 5% is transformed to cost-free tocopherol, providing useful antioxidant results. Due to the fact that the phenolic hydroxyl groups are blocked, tocopherol acetate is used as a substitute for tocopherol itself, providing a less acidic item with a much longer shelf life. It is thought that once taken in right into the skin, acetate is gradually hydrolyzed to restore tocopherols, giving sun protection.
  2. Vitamin E Acetate Adalah is utilized for biochemical research study; clinical drugs are fat-soluble vitamins, as well as are medically made use of for the therapy of habitual abortion, intimidated abortion, infertility and also menopausal conditions.

Vitamin E Acetate Adalah Pharmacological Actions and Applications

Vitamin E Acetate Adalah is the most commercially available form of vitamin E. In recent years, domestic and foreign experts and scholars have conducted extensive and in-depth research on the physiological and pharmacological effects of vitamin E. At present, it has been found that the main functions of vitamin E are: increasing the utilization rate of oxygen, improving the tolerance of myocardium to hypoxia, improving coronary blood circulation; blocking the peroxidation process of fatty acids in the body, interfering with free radicals and pigmented spots Therefore, it can protect the integrity and stability of the cell membrane, maintain the activity of enzymes, and improve the immune function of the human body; promote blood circulation of capillaries, accelerate the supply of nutrients in human tissues and eliminate metabolites, and reduce fatigue; prevent cholesterol deposition and maintain arteries. Elasticity, preventing thrombosis; promoting the synthesis of hemoglobin in the bone marrow, normal development of red blood cells; restoring the normal secretion of hydrochloric acid in the stomach, protecting epithelial cells, and improving local circulation. After a large number of clinical experiments, it was found that vitamin E can be used to prevent and treat menopausal syndrome, malnutrition, capillary circulation disorders, hyperlipidemia, vulvar atrophy, coronary heart disease, atherosclerosis, prevention of gallstone formation and treatment of anemia, digestion Ulcer, liver disease, nervous system disease, rheumatism, morphine addiction, atrophic rhinitis and various skin diseases, etc. But not taking large amounts of vitamin E will get the best results. Chang Yiyong found that taking a moderate amount of vitamin E can treat epilepsy in children, treat age spots, and cancer, but taking too much can induce cancer.

According to reports, if the daily dose of vitamin E reaches 400 mg to 800 mg for a long time, it can cause blurred vision, breast enlargement, headache, dizziness, nausea, and stomach cramps. Long-term consumption of more than 800mg/d will change the endocrine metabolism, resulting in decreased immune function. In addition, vitamin E can also be used for the preservation of fruits, vegetables, frozen fish, frozen meat and canned food.

Vitamin E Acetate Adalah Preparation

A preparation method of Vitamin E , is characterized in that, comprises the following steps:

(1) in reaction solvent, add 2,3,5-trimethylhydroquinone and the catalyzer that is made up of vitriol oil, copper sulfate, tin chloride, stir until material is dissolved, under N protection, temperature is controlled 30-33 ℃ , add isophytol dropwise within 3-3.5h, after the dropwise addition is completed, the temperature is raised to 62-66°C, the reaction is incubated for 2.5h, the reaction is completed, the liquid is separated, the solvent is recovered by distillation under reduced pressure, the reaction solution is washed, and vitamin E is extracted. Wash with ionized water until the pH of the solution is 7, wherein the mass ratio of isophytol to 2,3,5-trimethylhydroquinone is 2-2.5:1, copper sulfate to 2,3,5-trimethylhydroquinone The mass ratio of tin chloride and 2,3,5-trimethylhydroquinone is 0.006-0.012:1, and the mass ratio of concentrated sulfuric acid and 2,3,5-trimethylhydroquinone is 0.045-0.05:1. The mass ratio is 0.2-0.4:1;

(2) adding acetic anhydride and sodium borohydride to the vitamin E layer washed in step (2), under the protection of N, the temperature is raised to 126-130 ° C for esterification reaction for 3.5h, the reaction is completed, and acetic anhydride is recovered by vacuum distillation, Cross-washed with water and 70-80% methanol until the pH of the eluate is 7, washed twice, concentrated under reduced pressure at 50-60 °C, recovered petroleum ether, and concentrated to obtain Vitamin E Acetate Adalah, wherein acetic anhydride and 2,3 , The weight ratio of 5-trimethylhydroquinone is 2.3-2.7:1, and the amount of sodium borohydride added is 0.1-0.16% of the mass of acetic anhydride.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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