Vitamin B6 Powder deficiency includes two types of vitamin B6 deficiency and vitamin B6 dependence. In a narrow sense, vitamin B6 deficiency refers to a disease caused by insufficient intake of vitamin B6 from food or by taking certain drugs to inactivate vitamin B6. Vitamin B6 Powder dependence refers to patients who consume the amount of vitamin B6 required by healthy people, but still have vitamin B6 insufficiency, which is mostly a hereditary disease. With a normal diet, vitamin B6 deficiency is rare. At present, most of the vitamin B6 deficiency seen clinically is caused by taking vitamin B6 antagonists such as isoniazid, cycloserine, penicillamine, etc.; a few are caused by malignant tumors, severe liver and kidney diseases, and chronic alcoholism; Improperly fed babies and elderly people with poor appetite can also get sick. Main clinical manifestations: skin and mucous membrane inflammation, common seborrheic and desquamative dermatitis, stomatitis, glossitis, ophthalmia, etc. Followed by mental and neurological symptoms, such as nervousness, depression, lethargy, nausea, loss of vibration and position sense, peripheral neuritis, etc. Vitamin B6 Powder deficiency leads to anemia caused by the blockage of heme synthesis and folic acid metabolism. It is hypochromic microcytic anemia, but it is not iron deficiency, but insufficient utilization of iron. Excess iron is deposited in the liver, spleen, Bone marrow, liver and spleen may appear clinically.
In addition, infants and young children lack of vitamin B6 can still experience growth retardation, weight loss, weight loss and other growth and development abnormalities. The diagnosis of vVitamin B6 Powder deficiency in the narrow sense: it can be established mainly based on medical history, symptoms, signs and necessary laboratory tests. After oral administration of 100 mg/kg of tryptophan, the excretion of xanthuric acid in urine can be measured, which can measure the nutritional status of vitamin B6 in the body. The most effective way to treat vitamin B6 deficiency is to add a lot of vitamin B6. Patients taking a large amount of isoniazid or penicillamine should also take an appropriate amount of Vitamin B6 Powder to prevent peripheral neuritis caused by isoniazid and optic neuritis caused by penicillamine. TB patients with a history of seizures should be routinely given Vitamin B6 Powder when they must take isoniazid to prevent seizures.
