Vitamin B6 Liquid deficiency includes narrow vitamin B6 deficiency and vitamin B6 dependence. Vitamin B6 deficiency in a narrow sense refers to a disease caused by insufficient intake of vitamin B6 from food or taking certain drugs to inactivate vitamin B6. Vitamin B6 dependence refers to patients who ingest the amount of vitamin B6 required by healthy people, but still have vitamin B6 deficiency symptoms, which are mostly hereditary diseases. Normal diet, vitamin B6 deficiency rarely occurs. Most of the vitamin B6 deficiency seen clinically is caused by taking vitamin B6 antagonists such as isoniazid, cycloserine, penicillamine, etc.; a few are caused by malignant tumors, severe liver and kidney lesions, and chronic alcoholism; Improperly fed infants and elderly people with poor appetite can also get sick. Main clinical manifestations: skin and mucous membrane inflammation, common seborrheic and desquamative dermatitis, stomatitis, glossitis, ophthalmia, etc. Followed by mental and nervous system symptoms, such as nervousness, depression, drowsiness, nausea, loss of vibration and position sense, peripheral neuritis, etc. Vitamin B6 deficiency leads to hemoglobin synthesis and folic acid metabolism blockage and causes anemia, which belongs to hypochromic microcytic anemia, but it is not iron deficiency, but iron utilization is insufficient, and excess iron is deposited in the liver, spleen, spleen and stomach in the form of ferritin. Bone marrow, hepatomegaly and splenomegaly may appear clinically. In addition, infants and young children who lack Vitamin B6 Liquid may still experience growth retardation, emaciation, weight loss and other growth and development abnormalities.
Diagnosis of vitamin B6 deficiency in a narrow sense: it can be established mainly based on medical history, symptoms, signs and necessary laboratory tests. After taking tryptophan 100mg/kg orally, measure the excretion of xanthuric acid in urine, which can measure the nutritional status of vitamin B6 in the body. If the excretion is higher than 25mg and 75mg within 6 hours and 24 hours respectively, it is considered that the body is deficient in vitamin B6.
The most effective way to treat vitamin B6 deficiency: add a lot of Vitamin B6 Liquid. Patients taking a large amount of isoniazid or penicillamine should also take appropriate amount of vitamin B6 to prevent peripheral neuritis caused by isoniazid and optic neuritis caused by penicillamine. Tuberculosis patients with a history of seizures should be routinely given vitamin B6 when taking isoniazid to prevent seizures.
