Zhishang Chemical

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Zhishang Chemical

Vitamin B12 CAS 68-19-9

Molecular Formula:C63H88CoN14O14P

Formula Weight:1355.37

Purity: 98%

Product Name: Vitamin B12
CAS No: 68-19-9

Basic Info

Product Name:Vitamin B12
Other Names:hemomin
Place of Origin:Shandong, China
Brand Name:Zhishang Chemical
Type: Pharmaceutical raw materials
Appearance:Red powder
EINECS No.:200-680-0
Storage:Cool Dry Place
Provide:Vitamin B12 MSDS;
Vitamin B12 COA


Product Categories:

Small molecule inhibitors; Small molecule inhibitors, natural products; Pharmaceutical raw materials; Other medicine; Pharmaceutical raw materials – scientific research raw materials; Organic chemical raw materials; intermediate;Food and feed additives; Vitamin series; Biochemical reagents – vitamins; Organometallics;

Biochemistry; ClassesofMetalCompounds; Co(Cobalt)Compounds; NutritionalSupplements; Vitaminsandderivatives; VitaminIngredients; Carbohydrates&Derivatives; Intermediates&FineChemicals; Vitaminseries; Cobalamin,vitaminB-12; vitamin;Pharmaceuticalintermediates; Plant extracts;

Raw materials; Inhibitors; Reference substance – traditional Chinese medicine reference substance; Standard – standard of traditional Chinese medicine; Daily chemical raw materials; Vitamin drugs; Biochemical reagent – Vitamin; Medical raw materials; New products; Food additives, spices; Chemical materials;

Intermediate – API; Pharmaceutical raw materials; additive; Organic chemical raw materials; Pharmaceutical, pesticide and dye intermediates; Other chemical products; Porphyrins; TransitionMetalCompounds; Vitamins


Vitamin B12, abbreviated as VB12, also known as cobalamin, is one of the B vitamins. It is a kind of complex organic compounds of Gulin containing cobalt. The trivalent cobalt is located in the center of the Gulin ring plane similar to porphyrin. It is the largest and most complex vitamin molecule found at present, and it is also the only vitamin containing metal ions; Its crystal is red, so it is also called red vitamin.

Plants do not contain VB12 and cannot make VB12. Liver is the best source of VB12, followed by milk, meat, eggs, fish and so on. VB12 is an essential coenzyme in the synthesis of RNA and deoxyribonucleic acid. The lack of VB12 in vivo can cause pathological changes of nervous system such as peripheral nerve and central encephalopathy.

Chemical Properties:
Melting point >300°C
alpha 23656 -59 ± 9° (dil aq soln)
Boiling point >300 °C
Fp 9℃
storage temp. 2-8°C
solubility Sparingly soluble in water and in ethanol (96 per cent), practically insoluble in acetone. The anhydrous substance is very hygroscopic.
pkapKa 3.28±0.04(H2O,D2O t=23±0.5 Iunspeci?ed) (Uncertain)
form Powder
color Red 
Water Solubility Soluble
Sensitive Hygroscopic
Merck 14,10014
BRN 4122889

  1. It is mainly used to treat various VB12 deficiency diseases, such as megaloblastic anemia, anemia caused by drug poisoning, aplastic anemia and leucopenia; When used in combination with pantothenic acid, it can prevent malignant anemia and contribute to the absorption of Fe2 + and the secretion of gastric acid; It is also used to treat arthritis, facial paralysis, trigeminal neuralgia, hepatitis, herpes, asthma and other allergies, allergic dermatitis, measles, eczema and bursitis; VB12 can also be used for the treatment of neuroticism, irritability, insomnia, memory loss and depression.

  2. New research shows that VB12 deficiency can also cause mental diseases such as depression. VB12 is very safe as a therapeutic agent or health care product. VB12 more than thousands of times RDA was injected intravenously or intramuscularly, and no poisoning was found.

  3. VB12 can promote the growth and development of poultry and livestock, especially young poultry and livestock, and improve the utilization rate of feed protein, so it can be used as feed additive. Treating fish eggs or fry with VB12 aqueous solution can improve the tolerance of fish to toxic substances such as benzene and heavy metals in water and reduce mortality. At present, most of VB12 produced in the world is used in feed industry.

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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