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Vitacid Retinoic Acid CAS 302-79-4

Molecular Formula: C20H28O2

Formula Weight: 300.44

ZSpharmac: Vitacid Retinoic Acid Supplier

Product Name: Vitacid Retinoic Acid
CAS No: 302-79-4
Purity: 99%

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Basic Info

Product Name:Vitacid Retinoic Acid
Other Names:Retinoic Acid
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Yellow Powder
EINECS No.:206-129-0
Provide:Vitacid Retinoic Acid MSDS;
Vitacid Retinoic Acid COA

What is Vitacid Retinoic Acid?

Vitacid Retinoic Acid is a typically used medication in dermatology. It is an intermediate product of vitamin A (dimethanol) metabolic process in the body. It usually affects bone development as well as likewise epithelial metabolic rate, can market the spreading and also revival of epithelial cells, and can inhibit the spreading along with distinction of keratinocytes., to bring back hyperkeratosis to normal, so it has a specific recovery effect on lots of conditions with total keratosis, incomplete keratosis, in addition to hyperkeratosis, and also can deal with a choice of skin diseases. Topical application penetrates the skin rapidly as well as can significantly boost epithelial cell revival. This training course of medicines has a solid and also quick inhibitory result on the secretion of sebaceous glands, which can reduce sebum secretion. In addition to that, this product also has anti-tumor, wound recovery in addition to anti-infection influences.

Vitacid Retinoic Acid Property

Melting point 180-181 °C (lit.)
Boiling point 381.66°C (rough estimate)
density 1.0597 (rough estimate)
refractive index 1.4800 (estimate)
storage temp. -20°C
solubility Practically insoluble in water, soluble in methylene chloride, slightly soluble in ethanol (96 per cent).
form powder
color yellow
Water Solubility insoluble


Vitacid Retinoic Acid Uses

1. Acne removal
Vitacid Retinoic Acid has anti-inflammatory effects, and can also inhibit the secretion of hair follicle skin glands and promote the normalization of cell growth, improving the accumulation and blockage of keratin inside and outside the pores.

2. Delicate skin
Vitacid Retinoic Acid can promote the production of keratinocytes, making the stratum corneum firm; promote the production of intercellular matrix, make the skin firm and smooth, and make the pores less obvious.

3. Anti-photoaging
The main cause of photoaging is the increase of matrix metalloenzyme (MMP) in the decomposed collagen in the dermis caused by ultraviolet rays. The main function of MPP is to metabolize collagen. Retinol fights photoaging by preventing this action. At the same time, Vitacid Retinoic Acid can also promote the production of collagen and reduce skin problems such as fine lines and wrinkles.

4. Whitening
Retinol can accelerate the metabolism of keratinocytes, inhibit the production of melanocytes, and improve pigmentation (equivalent to the effect of freckle removal)~
After reading the above effects, do you understand why retinoids are so popular? It’s simply an ‘all-in-one’ ingredient.
The general effect is: Vitacid Retinoic Acid (vitamin A acid) > retinal (vitamin A aldehyde) > retinol (vitamin A alcohol) > retinol (vitamin A ester)
However, when retinoid substances bring so many effects, there are also many unacceptable side effects.

Precautions for Vitacid Retinoic Acid

(1) Those who dislike this product, those that dislike vitamin A by-products, people with intense or subacute dermatitis, eczema-like skin diseases, and also expecting women are contraindicated.
( 2) Those with allergies need to use it with caution.
( 3) Breast feeding ladies ought to quit breastfeeding throughout the drug period, and ladies of childbearing age are purely restricted from conceiving throughout the medicine period. Usage with care in children.
( 4) This item should prevent contact with eyes as well as other mucous membrane layers (such as mouth, nose, etc). It is not appropriate for use on skin folds up as well as skin ulcers.
( 5) If there is a burning feeling, itching, inflammation and also swelling at the drug website, the drug needs to be quit, and the regional medication needs to be cleaned off, and also speak with a medical professional if essential.
( 6) For the treatment of acne, it may briefly magnify in the first few weeks, as well as the therapy must be continued for greater than 6 weeks to achieve the optimal impact.
( 7) This item is not ideal for big location application, and the day-to-day dosage ought to not exceed 20g.
( 8) Do not utilize various other medicines, cosmetics or cleaning up agents that can trigger skin irritation as well as damages throughout the medication, so as not to aggravate skin responses, boost medication absorption and also cause systemic damaging reactions.
( 9) Sunlight can intensify the stimulation of retinoic acid to the skin and cause the decomposition of Vitacid Retinoic Acid. Pet experiments suggest that retinoic acid can boost the capacity of ultraviolet rays to create cancer. Therefore, this product is finest applied during the night as well as prior to going to bed, as well as sunlight direct exposure need to be avoided during the therapy process., or adopt shielding procedures.

Can Vitacid Retinoic Acid be Used to Treat Hair Loss?

Later studies found that, in addition to treating acne, topical vitamin A also has the effect of reversing the atrophy of epidermis and subcutaneous tissue, making fibronectin and collagen recover rapidly, which is more obvious for some skin aging (such as sun-induced skin aging). improved effect.

So many women use Vitacid Retinoic Acid or retinol to anti-aging (acid brushing), but this thing is a prescription drug, and this black technology still has certain risks.

As for whether Vitacid Retinoic Acid can improve hair loss, it can be said with certainty that it has an effect, but it has a scope of application and is not suitable for everyone.

1. Retinoic acid can inhibit the formation of acne and dissolve acne, and has the ability to dissolve fat, which is helpful for some patients with seborrheic dermatitis.

2. Retinoic acid has anti-inflammatory properties.

3. Retinoic acid can improve the skin damage caused by corticosteroids, and the components of cortisols are also a cause of hair loss.

4. Vitacid Retinoic Acid can promote hair follicle differentiation, up-regulate growth factors, and directly promote hair growth.

“Chinese Dermatology” once had a study on vitamin A acid and hair loss, the name is “Minoxidil and vitamin A acid combined external use in the treatment of alopecia areata”.

One group was treated with 0.05% tretinoin cream combined with 2% minoxidil, and the other group was treated with 2% minoxidil alone.

The final results showed that the cure rate of tretinoin combined with minoxidil was 43.48%, while the cure rate of minoxidil alone was 20%.

It shows that vitamin A acid does have a significant activation effect on hair growth.

Of course, the above experiments are aimed at patients with alopecia areata, and are not completely equivalent to patients with androgenetic alopecia.

But tretinoin does have its own benefits.

In fact, this is very easy to understand. Retinoic acid can be understood as an activator of epithelial cells, and hair follicle tissue will definitely benefit.

Some people may ask, since this thing works so well, why is it not promoted in hair loss treatment?

The reason is simple, the first tretinoin has certain side effects, and it is certainly impossible to use it for a long time like minoxidil.

The second is that hair loss is not a pathological problem, but a deep genetic cause, and the effect of Vitacid Retinoic Acid is not enough to reverse hair loss.

Therefore, the use of retinoic acid for hair loss patients needs to be combined with the specific situation. This is a prescription drug, and it needs to be used after a doctor’s diagnosis.

About Products:
If you need Vitacid Retinoic Acid, a cosmetic raw material, please contact our service staff directly, and we will provide you with high-quality products at the best price.
As an experienced Vitacid Retinoic Acid manufacturer and supplier, ZSpharmac will provide Vitacid Retinoic Acid raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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