Zhishang Chemical

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Zhishang Chemical

Vanillyl Butyl Ether CAS 82654-98-6

Molecular Formula: C12H18O3

Formula Weight: 210.27

ZSpharmac:  Vanillyl Butyl Ether Supplement

Product Name: Vanillyl Butyl Ether
CAS No: 82654-98-6
Purity: 99%

Basic Info

Product Name:Vanillyl Butyl Ether
Other Names:Vanillyl Butyl
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Light Yellow Liquid
EINECS No.:209-753-1
Storage:Sealed in Dry,Room Temperature
Provide:Vanillyl Butyl Ether MSDS;
Vanillyl Butyl Ether COA

What is Vanillyl Butyl Ether?

Vanillyl butyl ether CAS No. 82654-98-6, chemical formula C12H18O3, molecular weight 210.270000, Chinese alias vanillyl alcohol butyl ether, light yellow liquid, boiling point 307.9ºC at 760 mmHg, flash point 140ºC, density 1.048 g/cm3, refractive index 1.516. If inhaled vanillyl butyl ether, move the patient to fresh air; in case of skin contact, remove contaminated clothing, rinse skin thoroughly with soap and water, seek medical attention if discomfort occurs; in case of eye contact, Separate eyelids, rinse with running water or normal saline, and seek medical attention immediately; if ingested, rinse mouth immediately, do not induce vomiting, and seek medical attention immediately. The advice to protect rescuers is as follows: transfer the patient to a safe place, consult a doctor, and show this chemical safety data sheet to the doctor at the scene if conditions permit. In case of leakage, collect the leaked liquid in a sealable container as much as possible for a small amount of leakage, absorb it with sand, activated carbon or other inert materials, and transfer it to a safe place. It is forbidden to flush into the sewers; if there is a large amount of leakage, build a dike or dig a pit Contain, close the drainage pipe, cover with foam to suppress evaporation, transfer it to a tanker or a special collector with an explosion-proof pump, and recycle or transport it to a waste disposal site for disposal.

Vanillyl Butyl Ether Properties:

Boiling point 241 °C(lit.)
density 1.057 g/mL at 25 °C(lit.)
refractive index n20/D 1.516(lit.)
Fp >230 °F
storage temp. Sealed in dry,Room Temperature
solubility soluble (Insoluble in water. Soluble in organic solvents, oils.)
Specific Gravity1.057
JECFA Number888


Vanillyl Butyl Ether Application

Vanillyl butyl ether can be used as a cosmetic perfume for the preparation of other functional compositions. For example, vanillyl butyl ether is used to prepare a kind of cosmetic for chest massage using plant extracts, which is prepared from the following components according to mass percentage: glycerin 2%-8%, polyglycerol-10 1%-7% , hydroxyethyl acrylate 2%-10%, polydimethylsiloxane 1%-9%, vanillyl butyl ether 1%-9%, licorice root extract 5%-15%, peony root extract 3%-13%, wild chrysanthemum extract 5%-15%, mulberry root extract 9%-15%, phenoxyethanol 2%-8%, water 20%-40%. The preparation method is as follows: glycerin, polyglycerol-10, hydroxyethyl acrylate, polydimethylsiloxane, and vanillyl butyl ether are mixed together, and denoted as material I; , wild chrysanthemum extract, mulberry root extract, phenoxyethanol, and water are mixed together, and recorded as material II; material II and material I are mixed together, and the mixed material is homogenized; The mixture is cooled down.

Vanillyl Butyl Ether can also be used in the preparation of hand creams, such as a dragon fruit hand cream, consisting of the following ingredients: Dragon Fruit Pulp Extract, Vanillyl Butyl Ether, Chamomile, Lemon Peel Extract, Medicinal Vaseline . Further, calculated in parts by weight: 10-15 parts of dragon fruit pulp extract, 5-7 parts of vanillyl butyl ether, 3-4 parts of chamomile, 3-5 parts of lemon peel extract, 2-5 parts of medicinal vaseline 3 copies. Further, the best calculated by weight is: 13 parts of dragon fruit pulp extract, 6 parts of vanillyl butyl ether, 3.4 parts of chamomile, 4 parts of lemon peel extract, and 2.6 parts of medicinal vaseline. The hand cream has the advantages of fast absorption, anti-aging, good moisturizing and moisturizing effect, warm hands, and spot removal. , The added vanillyl butyl ether can warm the hands, make the hands hot when used in winter, and can prevent the hands from being cold and stiff. The added chamomile and lemon peel extracts are rich in vitamin C, which can prevent Hand aging and speckle removal, medicinal Vaseline can lock in moisture.

The Heating Principle of Vanillyl Butyl Ether

Vanillyl butyl ether is an exothermic agent with excellent performance, but what is the heating mechanism of its heating principle? This article will give you a detailed analysis from the perspective of biology.
The vanillyl group of vanillyl butyl ether is a functional group that plays a key role in inducing the sensation of warmth through the nervous system. Sensory neurons are activated by the binding of vanillyl to its receptor, called vanilloid receptor-1 (VR-1). It is a non-selective cation channel that naturally responds to noxious stimuli, such as high temperature or acidic pH. After ligand/receptor binding, the channel opens and results in the influx of primary calcium ions through the channel pore. This action, in turn, leads to membrane depolarization, which generates action potentials once the threshold is reached. The action potential then propagates the axon to the synapse for a long time.
Activated sensory neurons will release glutamate, ATP and various neuropeptides as synaptic neurotransmitters. These neurotransmitters eventually reach the central nervous system and emit a cascading sensation of warmth, which can also be triggered by temperatures ≥43°C. Among neurotransmitters, calcitonin gene-related peptide (CGRP), one of the known neuropeptides released upon activation, acts on vascular endothelial cells to trigger vasodilation, thereby increasing blood circulation.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Our Mission
Help China Chemicals to benefit the happiness of human life
Our Vision
Become the most trusted chemical supplier in the world
Our Business Philosophy
Striver – oriented, enrich employees, customer first, deep service, seek development
Our Valuse
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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