Ursolic Acid Supplements CAS 77-52-1

Molecular Formula: C30H48O3

Formula Weight: 456.71

ZSpharmac: Ursolic Acid Supplements Supplier

Product Name: Ursolic Acid Supplements

CAS No: 77-52-1

Purity: 99%

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Basic Info

Product Name:	Ursolic Acid Supplements
Other Names:	Ursolic Acid
CAS:	77-52-1
Place of Origin:	Shandong, China
Brand Name:	ZSpharmac
Type:	Cosmetic Raw Materials
Appearance:	White to Off-White Crystalline Powder or Needles
EINECS No.:	201-034-0
Storage:	2-8°C
Provide:	Ursolic Acid Supplements MSDS； Ursolic Acid Supplements COA

What is Ursolic Acid Supplements?

Ursolic Acid Supplements, likewise known as ursolic acid as well as ursolic acid, is a pentacyclic triterpenoid compound removed from the evergreen sneaking plant shrub Ursolicaceae of Rhododendronaceae. It has a special smell and also is big as well as shiny in straight-out ethanol Prisms, as well as needle crystals as great as hair in thin down ethanol. It has different biological outcomes such as sedative, anti-inflammatory, anti-bacterial, anti-diabetic, anti-ulcer, along with lowering blood glucose degree. In the last couple of years, it has in fact been located that it has anti-carcinogenic, anti-cancer, induction of F9 teratoma cell distinction and likewise anti-angiogenesis impacts, and it is most likely to come to be a new type of anticancer medication with reduced poisoning as well as likewise high efficiency. Additionally, Ursolic Acid Supplements has obvious anti-oxidation feature as well as additionally is a strong anti-oxidant. The anti-oxidation impact of ursolic acid has beneficial effects on body’s anti-aging, skin freckle elimination as well as pigment elimination, so it is thoroughly used as Medication and additionally all-natural whitening cosmetic raw materials, experiments have actually shown that ursolic acid can impede the task of 5-lipoxygenase as well as cyclooxygenase in the metabolic procedure of arachidonic acid, and also stop the advancement of prostaglandins in addition to leukotrienes, which may be ursolic acid Inhibit inflammatory feedback, prevent the reason for lipid peroxidation.

Ursolic Acid Supplements Property

Melting point	292 °C (dec.) (lit.)
alpha	59 º (c=0.3, pyridine)
Boiling point	502.79°C (rough estimate)
density	1.0261 (rough estimate)
refractive index	1.4940 (estimate)
storage temp.	2-8°C
solubility	Soluble in DMSO (up to 25 mg/ml with warming)
pka	4.68±0.70(Predicted)
form	Crystalline Powder or Needles
color	White to off-white
Water Solubility	insoluble

Efficacy and Function of Ursolic Acid Supplements

Ursolic Acid Supplements are a sort of triterpenoids existing in all-natural plants, which have different biological outcomes such as sedation, anti-inflammatory, antibacterial, anti-diabetic, anti-ulcer, as well as lowering blood glucose.Ursolic acid also has evident antioxidant function, Additionally, ursolic acid can additionally display its anticancer activity by inducing apoptosis, hindering cell cycle development, hindering cell spreading, preventing metastasis, and also decreasing tumorigenesis via different signaling paths.

Current experimental researches have shown that ursolic acid hinders a range of cancers cells, including bladder cancer cells, colon cancer, breast cancer cells, cervical cancer, gastric cancer, glioma, neuroblastoma, fibrosarcoma, liver cancer, leukemia, several myeloma, lung cancer cells, ovarian cancer cells, pancreatic cancer, thyroid cancer cells, melanoma and also prostate cancer cells, etc. In order to better recognize as well as study the impact of ursolic acid on cancer cells and also open up a new chapter in chemotherapy, scientists have actually conducted different in vivo as well as in vitro researches.

Comparison of Arbutin and Ursolic Acid Supplements

Ursolic Acid Supplements are a type of triterpenoids present in natural plants, which have different organic results such as sedative, anti-inflammatory, anti-bacterial, anti-diabetic, anti-ulcer, and also reducing blood sugar. In recent years, it has actually been located that it has anti-carcinogenic, anti-cancer, induction of F9 teratoma cell distinction and also anti-angiogenesis effects, as well as it is most likely to become a new kind of anticancer medication with reduced toxicity as well as high performance. Ursolic acid is a strong anti-oxidant. Experiments have shown that Ursolic Acid Supplements can stop the job of 5-lipoxygenase as well as cyclooxygenase in the process of arachidonic acid metabolic process, and protect against the manufacturing of prostaglandins as well as additionally leukotrienes. source of oxides. Researches by Subbaramaiah et al. have shown that ursolic acid can hinder the transcription of cyclooxygenase in human bust epithelial cells, consequently inhibiting the manufacturing of prostaglandins. The antioxidant effect of Ursolic Acid Supplements has a beneficial effect on the anti-aging of the human body, skin acne removal, as well as pigment elimination. Among the 29 licenses on ursolic acid in Japan from 1983 to 2004, 10 have to do with the application of Ursolic Acid Supplements in skin elegance and health care. As a cosmetic, ursolic acid is secure, its color along with fragrance do not transform with time, and also it has It has a great touch sensation, so it is commonly made use of in appeal as well as skin treatment products, and additionally it is a natural raw material for lightening cosmetics. the

α-Arbutin can fix skin problems triggered by ultraviolet rays, restore the openness of the skin, and additionally is not promptly disintegrated by β-glucosidase on the skin surface area. The influence pertains to 10 times that of β-arbutin, and also it can remain in the skin for an extended period of time.Every edge of the skin, continuously safeguards the skin from problems. Melanin is the reason for regular skin. α-Arbutin can quickly penetrate deep right into the skin in addition to inhibit the job of tyrosinase in the pigment mom cells deep in the stratum corneum. And it creates a twin impact on the surface area of the skin, preventing the production of melanin.

Determination of Ursolic Acid Supplements in Plants

(1) Chromatographic problems: silica gel G thin-layer plate; cyclohexane-chloroform-ethyl acetate (20:5:8) as developing representative, upward development; advancement range 12-18cm; 5% sulfuric acid ethanol solution, warmed at 110 ° C 5min for color growth.
( 2) Prep work of reference substance service: Precisely weigh a suitable quantity of Ursolic Acid Supplements reference compound, include anhydrous ethanol: ethanol (3:2) mixed remedy to make a remedy consisting of 1 mg per ml, as the recommendation substance option.
( 3) Preparation of the example option: accurately consider 20 g of the crushed gardenia example (the fried gardenia is weighed according to the yield), placed it in a Soxhlet extractor, add 300 ml of ether to reflux and essence till colorless, as well as recover the solvent to dryness. Soak the deposit in petroleum ether two times, 15ml each time, for concerning 2min, pour off the petroleum ether, liquify it with anhydrous ethanol-ether (2:3) mixture with slight warmth, and also set the volume in a 5ml measuring container as an example solution.
( 4) Determination: Accurately draw 2 μl of the example service and also the referral service, and spot on the very same thin-layer plate. According to the above chromatographic problems, develop and create color. Checking according to the thin-layer scanning technique, λS=520nm, λR=700nm; dual-wavelength reflection zigzag scanning; SX=3.0; slit: 1.20 mm × 1.2 mm; paper speed: 20mm/min. Procedure the absorbance essential value of the example and referral compound, and determine the material of Ursolic Acid Supplements.

About Products:
If you need Ursolic Acid Supplements this cosmetic raw material, please contact our service personnel directly, we will provide you with high-quality products at the best price.
As an experienced Ursolic Acid Supplements manufacturer and supplier, ZSpharmac will provide Ursolic Acid Supplements raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile：

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture：

OUR MISSION
Help China Chemicals to benefit the happiness of human life
OUR VISSION
Become the most trusted chemical supplier in the world
OUR BUSINESS PHILOSOPHY
Striver – oriented, enrich employees, customer first, deep service, seek development
OUR VALUES
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info

Business Type: Manufacturer
Product Range: Cosmetic raw materials
Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
Total Employees: 51~100
Capital (Million US $): 10000000RMB
Year Established: 2016

Production Capacity

No. of Production Lines : 8
No. of QC Staff : 5 -10 People
OEM Services Provided : yes
Factory Size (Sq.meters) : 3,000-5,000 square meters
Certificate: ISO9001 , CE , GMP , API , MSDS
Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.

Service

Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.

After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.

FAQ

Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.

HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?

You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

Is there a discount?

Different quantity has different discount.

Shipping

1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.