Zhishang Chemical

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Zhishang Chemical

Tyrosine Pure CAS 60-18-4

Molecular Formula: C9H11NO3

Formula Weight: 181.19

ZSpharmac: Tyrosine Pure Supplier

Product Name: Tyrosine Pure
CAS No: 60-18-4
Purity: 99%

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Basic Info

Product Name:Tyrosine Pure
Other Names:L-Tyrosine
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White to Pale-Brown Powder
EINECS No.:200-460-4
Storage:Store Below +30°C.
Provide:Tyrosine Pure MSDS;
Tyrosine Pure COA

What is Tyrosine Pure?

Tyrosine Pure is a fragrant amino acid that exists in various proteins, specifically rich in milk casein. It consists of a phenol group in its particle and also its architectural formula is:

酪氨酸 结构式

Tyrosine Pure was discovered by Li Biqi from casein in 1846. It is a white crystalline powder that takes shape right into needles or flakes from water. The family member density is 1.456 (20 ° C), the isoelectric factor is 5.66, as well as it has the ability to absorb ultraviolet rays. It has the optimum light absorption at the wavelength of 274nm, and also can minimize phosphomolybdic acid-phosphotungstic acid reagent (Folin reagent). Melting point: Levorotatory body decays at 290-295 ° C(slow-moving home heating), 314-318 ° C(fast heating), racemic body decays at 290-295 (slow-moving home heating), 340 ° C(quick home heating). Soluble in water, ethanol, acid as well as antacids, insoluble in ether. The aqueous option of D-isomer responds with tyrosinase as well as reddens. The left-handed body can triboluminescence, and it can be transformed right into a racemate when heated with barium hydroxide liquid service at 170 ° C. The ortho-position of the phenolic hydroxyl team in the tyrosine molecule is prone to chemical reactions, and it is paired with diazobenzenesulfonic acid to acquire an orange-red compound, which works with boiling The activity of thin down acetic acid and salt nitrite is purple or red, the activity of warm nitric acid is yellow, and the action of titanium dioxide in sulfuric acid is dark orange yellow. All-natural tyrosine is a left-handed body, which can be gotten by hydrolyzing as well as refining proteins.

Tyrosine Pure is a non-essential amino acid, which is a basic material for numerous body items. Tyrosine can be converted into numerous physical materials through different metabolic paths in the body, such as dopamine, adrenaline, thyroxine, melanin and poppy (opium) of papaverine. These materials are closely related to the control of nerve conduction and metabolic guideline. Studying tyrosine metabolism assists to understand the pathological procedure of particular illness. As an example, alkapsis is connected to tyrosine metabolism problem. The absence of alkapsis oxidase in the body of the client triggers the metabolite of tyrosine, alkapsis, to stop working to decay, and it is excreted from the urine and also oxidized into a black compound airborne. Kid’s diapers will slowly turn black when subjected to the air, and the pee will likewise transform black after a long time. Albinism is additionally associated with the metabolic rate of Tyrosine Pure. People lack tyrosinase to ensure that the tyrosine metabolite 3,4-dihydroxyphenylalanine can not develop melanin, to ensure that the hair and also skin are white.

Tyrosine Pure Property

Melting point 

>300 °C (dec.) (lit.)


-11.65 º (c=5,DIL HCL/H2O 50/50)

Boiling point 

314.29°C (rough estimate)



refractive index 

-12 ° (C=5, 1mol/L HCl)


176 °C

storage temp. 

Store below +30°C.


1 M HCl: 25 mg/mL




2.2(at 25℃)


White to Pale-brown


6.5 (0.1g/l, H2O)

optical activity

[α]20/D 11.5±1.0°, c = 4% in 1 M HCl

Water Solubility 

0.45 g/L (25 ºC)



Tyrosine Pure Uses

  1. Tyrosine Pure is an amino acid utilized in cosmetics to boost the tanning process. L-Tyrosine helps enhance melanin manufacturing when UV rays exist, resulting in quicker, darker sun tanning.
  2. Tyrosine Pure is an amino acid drug. Resources for amino acid mixture and amino acid compound preparation, made use of as dietary supplement. For the therapy of polio and tuberculous encephalitis/ hyperthyroidism and also various other conditions.
  3. Tyrosine Pure is a nutritional supplement. After co-heating with sugars, the aminocarbonyl reaction can produce special scent compounds. It is utilized medicinally to treat hyperthyroidism.
  4. Tyrosine Pure is utilized in biochemical research, as well as it is used as an amino acid nutritional medication in medicine to treat polio, sleeping sickness, hyperthyroidism and also other conditions.
  5. Tyrosine Pure is made use of in medicine to deal with myelitis, tuberculous sleeping sickness, hyperthyroidism and also other conditions, as well as is likewise made use of to produce L-dopa diiodotyrosine. After co-heating with sugars, the aminocarbonyl response can produce special fragrance compounds.
  6. Tyrosine Pure is the standard for the resolution of nitrogen in amino acids. Prepare tissue society medium. Colorimetric quantitative analysis was performed making use of the Mylon response (protein shade reaction). It is the major basic material for the synthesis of various peptide hormones, antibiotics and other drugs.
    Amino acid precursors of dopamine as well as catecholamines.

How Tyrosine Pure is Produced

Tyrosine Pure is mainly prepared by protein hydrolysis extraction. Raw materials such as pig blood meal, horned hoof, and silk can be used, hydrolyzed with acid, and then separated and purified.
Pig blood meal [HCl (hydrolysis)]→[110℃, 24h] hydrolyzate [acid removal]→[evaporative concentration]acid removal solution[activated carbon]→decolorization solution[decolorization, cooling and crystallization]→L-tyrosine crude product[activated carbon (refinement)]→[90℃,30min] filtrate [crystallization]→Tyrosine Pure.
Hydrolysis and acid removal Put pig blood powder, water, and industrial hydrochloric acid into the hydrolysis tank at a weight ratio of 1:1.3:1, heat to 112-114°C, stop stirring and reflux for 24 hours, cool and filter to get the filtrate, which is the hydrolyzate . Evaporate and concentrate the hydrolyzate to a syrupy state, add water to dissolve and evaporate to concentrate, and repeat this three times to catch acid.
Add distilled water to dilute the decolorized and crystallized concentrated solution until it is completely dissolved, then add heavy ammonia water to adjust the pH value of the solution to 3.5, add 1% activated carbon, stir and boil for 10 minutes, stir and heat in a water bath at 90°C for 30 minutes, filter while it is hot, and wash the activated carbon layer with distilled water for 3 minutes Once, the filtrate and washings were combined. According to this method, continue to decolorize with activated carbon until the solution is light yellow. The filtrate was placed below 10°C and stood still for 24 hours, and crystals were precipitated, and the crude product of Tyrosine Pure was obtained by filtration.
Recrystallization and refining Add the crude tyrosine to distilled water at a ratio of 1:20, let it completely dissolve, then add 1% activated carbon, keep stirring at 90°C for 30 minutes, filter while it is hot, and cool and refine the filtrate to precipitate crystals. The crystals were collected by filtration, washed twice with absolute ethanol, and dried at 60°C to obtain the finished product of Tyrosine Pure.

About Products:
If you need L-Tyrosine as a cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced L-Tyrosine manufacturer and supplier, ZSpharmac will provide L-Tyrosine raw materials for customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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