Zhishang Chemical

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Zhishang Chemical

Triclocarban Protex CAS 101-20-2

Molecular Formula: C13H9Cl3N2O

Formula Weight: 315.58

ZSpharmac: Triclocarban Protex Supplier

Product Name: Triclocarban Protex
CAS No: 101-20-2
Purity: 99%

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Basic Info

Product Name:Triclocarban Protex
Other Names:Triclocarban
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Fine Plates Neat
EINECS No.:202-924-1
Storage:Sealed in Dry,Room Temperature
Provide:Triclocarban Protex MSDS;
Triclocarban Protex COA

What is Triclocarban Protex?

Triclocarban Protex (English: Triclocarban, abbreviated TCC) is an antibacterial chemical, originally used in medicine and later in soaps and hand sanitizers, but is no longer commonly used. TCC can effectively inhibit the growth of Staphylococcus aureus (Staphylococcus aureus), but its mechanism of action is still unclear. Triclocarban Protex has produced some drug resistance and environmental pollution, and can also disrupt endocrine.

Triclocarban Protex Property

Melting point 254-256 °C (lit.)
Boiling point 344.2±42.0 °C(Predicted)
density 1.5732 (rough estimate)
vapor pressure <0.1 mm Hg ( 25 °C)
refractive index 1.6300 (estimate)
Fp 150 °C
storage temp. Sealed in dry,Room Temperature
solubility methanol: soluble
form neat
color Fine plates
Water Solubility <0.1 g/100 mL at 26 ºC


Triclocarban Protex Uses

  1. Triclocarban Protex is utilized as a bacteriostat and also disinfectant in soaps and also other cleansing make-ups. Antiseptics, anti-bacterials.
  2. Triclocarban Protex is a bacteriostatic representative in household chemicals. It has continuous, risk-free, and steady bactericidal characteristics, has excellent compatibility with the skin, and has high-efficiency inhibitory results on Gram-positive microorganisms, Gram-negative microorganisms, fungi, yeasts, and viruses.
  3. Triclocarban Protex has anti-bacterial impact as well as is widely made use of in washing powder, soap, shower gel, etc.

Regulatory Actions on Triclosan and Triclocarban Protex

In rinse-off products, the optimum permitted focus is 1.5%. Required to fulfill the pureness requirements: 3, 3′, 4, 4′-tetrachloroazobenzene ≤ 1ppm; 3, 3′, 4, 4′-tetrachloroazobenzene ≤ 1ppm.

Allowed preservatives, the optimum permitted concentration is 0.2%. Required to meet the pureness requirements: 3, 3′, 4, 4′- tetrachloroazobenzene < 1ppm; 3, 3′, 4, 4′- tetrachloroazobenzene < 1ppm.

In this evaluation, SCCS did not analyze the synchronised use of Triclocarban Protex and also triclosan in one item.

In 2010, the Aesthetic Basic Material Analysis Board (CIR) evaluated triclosan, and also the statistics reveal that when the dosage of triclosan in cosmetics is 0.01-0.3%, it is secure to use. According to the Japanese Aesthetic Regulations, Triclocarban Protex has no limitations on the use of “rinse-type cosmetics that are not used on mucous membrane layers”, while the amount of “residual cosmetics that are not utilized on mucous membranes” and also “cosmetics that are made use of on mucous membrane layers” is 0.03 % is safe to use. Triclosan is safe to use when the dose is 0.01% in the entire cosmetics.

The inquiry information of the China Cosmetic Resources Regulatory Database (Chinacosing) individually created by CIRS Team reveals that both triclocarban and also triclosan have been included in the directory of used cosmetic raw materials in my nation, and the listing of allowed preservatives in the “Safety And Security and also Technical Specs for Cosmetics” lists Triclocarban The optimum allowed concentration of Protex is 0.20%, and the purity criterion: 3, 3′, 4, 4′-tetrachloroazobenzene <1 mg/kg; 3,3′, 4, 4′-tetrachloroazooxy Benzene <1mg/kg. Triclosan is allowed to use a maximum focus of 0.30%. Other constraints: hand soap, bath soap, body wash, deodorant (not spray), makeup powder as well as concealer, nail cleaner (nail cleaner ought to not be made use of greater than once a week). If the enterprise utilizes this basic material in cosmetics, it requires to perform a security evaluation to ensure the safety and security of its use.

Physiological Toxicity of Triclosan

Through long-term research on triclosan and Triclocarban Protex, experts found that triclosan has the potential to damage the normal secretion of body hormones, induce DNA damage, and have genotoxicity.

Triclosan, an antibacterial chemical added to medicines and personal care products, has the potential to cause problems including cancer, reproductive dysfunction and developmental abnormalities. At the same time, Triclocarban Protex is also a new type of endocrine disruptor.

Triclosan has been identified as a RED-level pesticide by the U.S. Environmental Agency, and Triclocarban Protex is also listed as a mass-produced chemical substance with a potential high risk to aquatic organisms.

According to relevant studies, both triclosan and Triclocarban Protex can cause DNA breakage damage, and as the exposure dose and time of the two increase, the cell damage (OTM value) continues to increase, showing a significant dose-effect and time- effect.

However, there are still few studies on the effects of triclosan and triclocarban on human health, and further research is needed on the specific effects.

Relevant literature shows that the US FDA regularly conducts in-depth research on some commonly used chemical ingredients to understand their potential adverse effects on the human body and the environment, thereby urging companies to further develop new technologies and improve product formulations.

Although the research data of the American Cleaning Institute (ACI) also shows that based on the amount of triclocarban used in personal cleaning products and the environmental exposure, it is safe to the human body and the water environment, and has no predictable adverse effects.

However, the potential risks are:

When these two substances, which are widely produced and used in human daily necessities, are discharged with sewage after being used by the products, the sewage containing triclosan or Triclocarban Protex is discharged into the environment, which may have an impact on aquatic organisms and ecology , and the pollutants in the soil may be absorbed through the roots of crops, and after being amplified by the food chain, they will be eaten by the human body. When a certain amount reaches a certain amount, it may have adverse effects on the human body.

my country’s management of cosmetics

The ban affects about 40% of the products (approximately 2,100 products) in the U.S. antibacterial bath products market.

According to foreign news reports, the regulation will be fully implemented in the United States on September 2, 2017.

In fact most manufacturers are or have reformulated their products, they will use other antimicrobial ingredients: benzalkonium chloride, benzethonium chloride, chloroxylenol instead of triclosan or triclocarban.

The three ingredients FDA said it will delay the release of the use limit concentration or ban.

The antibacterial ingredients contained in common daily necessities on the market can contain the above three types.

The definition of cosmetics in China refers to daily products that are spread on any part of the human body (skin, hair, nails, lips, etc.) by rubbing, spraying or other similar methods to achieve the purpose of cleaning, eliminating bad smell, skin care, beauty and modification. Chemicals used. Cosmetics for special purposes fall into nine categories: hair growth, hair dyeing, perming, hair removal, breast enhancement, bodybuilding, deodorant, freckle removal, and sunscreen. Other than that, they are called non-special purpose cosmetics.

Soaps and body washes are non-special purpose cosmetics. In my country, triclosan and Triclocarban Protex are listed as restricted substances or preservatives, which are allowed to be used in limited quantities.

About Products:
If you need Triclocarban Protex, a cosmetic raw material, please contact our service staff directly, and we will provide you with high-quality products at the best price.
As an experienced Triclocarban Protex manufacturer and supplier, ZSpharmac will provide Triclocarban Protex raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Triclocarban Protex Quotation