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Trehalose Haworth CAS 99-20-7

Molecular Formula: C12H22O11

Formula Weight: 342.3

ZSpharmac: Trehalose Haworth Supplement

Product Name: Trehalose Haworth
CAS No: 99-20-7
Purity: 99%

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Basic Info

Product Name:Trehalose Haworth
Other Names:D-Trehalose Anhydrous
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White to Off-White Powder
EINECS No.:202-739-6
Storage:Inert Atmosphere,Room Temperature
Provide:Trehalose Haworth MSDS;
Trehalose Haworth COA

What is Trehalose Haworth?

Trehalose Haworth Exist in mold, algae, completely dry yeast, ergot, and so on, as well as can additionally be synthetically manufactured. It has the unique function of preserving organic vigor, and also can effectively secure the framework of cell membrane layers and also healthy proteins, to ensure that the microorganism can maintain the intracellular dampness under unusual problems, such as high-temperature dehydration (drying out, high osmotic pressure) as well as freezing, and also avoid the cells from dehydration. On top of that, Trehalose Haworth also has the qualities of maintaining biofilm as well as healthy protein framework in vitro. It is made use of worldwide to protect genetically engineered enzymes, different viruses, vaccines, antibodies, healthy protein variables, nucleic acids, and so on. At the same time, as a stabilizer and also safety agent for naturally energetic materials, it has broad application potential customers in the fields of food, health items, cosmetics, medicine, molecular biology and also agriculture.

Trehalose Haworth Properties

Melting point 203 °C
Boiling point 397.76°C (rough estimate)
density 1.5800
refractive index 197 ° (C=7, H2O)
RTECS LZ5776770
storage temp. Inert atmosphere,Room Temperature
solubility Soluble in water; very slightly soluble in ethanol (95%); practically insoluble in ether.
form Powder
color White to Off-white
Water Solubility Soluble in water.


Applications of Trehalose Haworth

It can be utilized as an excellent food preservative and anti-denaturation representative. According to relevant reports, adding 3% Trehalose Haworth to eggs and drying them right into powder at 45 ℃, the item after rehydration is practically the same as that of fresh egg liquid; The top quality continues to be the same for numerous years; the milk powder constructed from Trehalose Haworth is moisturized as well as reduced to fresh milk, and the sensory quality and nutrients continue to be primarily unmodified, which can not only decrease the transport quantity however additionally conserve the refrigeration devices, greatly lowering the expense. Usage in dairy, meat, fruit and also various other commodities usually extends the shelf life of these items as well as preserves great organoleptic top qualities of the food. It can additionally be made use of as an outstanding dehydrating representative to stop powder food from sticking. Because of its solid water absorption, adding Trehalose Haworth to starchy foods can significantly prevent the aging of starch as well as prolong the service life of the item. As a natural food sweetener with high stability, low sweetness and also anti-caries, it can be commonly utilized in numerous sweets, cakes, beverages and also spices.

Trehalose Haworth is a natural environment-friendly saccharide. Compared to other saccharides, it is taken in slowly in the human body as well as has a gentle blood glucose reaction, which can be made use of to create natural food for diabetics. It is likewise ideal for the development of sporting activities beverages and also practical drinks that provide enough power and alleviate tiredness as well as anxiety. It is likewise a proliferation aspect of bifidobacteria, which can promote the spreading of bifidobacteria in the human body, enhance the digestive micro-ecological environment, enhance the food digestion and absorption feature of the intestinal tract, successfully get rid of toxins in the body, and also enhance the immune resistance of the body. Furthermore, it additionally has the feature of stopping human weakening of bones, as well as is an important basic material for the development of different organic food.

As a details protective agent for biomolecules and a stabilizer for tissue cells. Such as blood products, injections, antibodies, enzymes, infections, hormonal agents, recombinant human healthy proteins, separated cells and tissues and other biologically energetic materials, compared with various other protective agents of Wanfang Data, not just can they be stored at room temperature level, but also It can additionally reduce the spread of liver disease B as well as AIDS triggered by blood air pollution, and also guarantee the top quality and security of biological items. The enhancement of dimethyl sulfoxide as well as Trehalose Haworth throughout the freezing procedure of islet cells made the recuperation price of mature islet cells get to 92%, which was 34% more than that of DMSO alone, and the feature was no various from that of freshly drawn out island cells. In addition, since there is no requirement for icy storage space, a huge quantity of cool chain storage space costs can be conserved.

Due to its strong moisturizing impact and also different physiological features such as sun block and UV protection, it can be included in creams, masks, significances, facial cleansers as a moisturizing representative, protective agent, etc, and also can also be used as lipstick, oral cleanser, Sugar and high quality improvers such as oral fragrances. The Japanese Forestry Research study Institute discovered that it likewise has the impact of preventing the body smell of the senior, as well as prepares to make use of Trehalose Haworth to establish cosmetics and care products to stop body odor. Anhydrous Trehalose Haworth can also be used in cosmetics as a dehydrating agent for phospholipids as well as enzymes, as well as its fat by-products are likewise outstanding surfactants.

Using biotechnology to present Trehalose Haworth synthase gene into crops and also express them in plants, construct transgenic plants producing trehalose, grow brand-new varieties of transgenic plants with resistance to cold as well as drought, improve the cold resistance and also dry spell resistance of crops, and can make It shows up fresh after gathering as well as retains its initial flavor as well as structure. At present, American researchers have presented the trehalose synthase genetics from yeast into cigarette, and obtained transgenic plants with dry spell resistance.

Trehalose Haworth Origin and Industrialization

Trehalose Haworth widely exists in lower ferns, algae, bacteria, fungi, yeast, insects and invertebrates, especially in fungi such as yeast and mold, and the content can be as high as 20% of the dry weight of the organism. How to extract and utilize it, and even realize large-scale industrial production, people have done a lot of research work. At present, the preparation methods of Trehalose Haworth include chemical synthesis method, microbial extraction method, microbial fermentation method, enzyme synthesis method, genetic engineering method and the like.

1. Microbial extraction method

Using yeast, lactic acid bacteria, mold and other microorganisms containing Trehalose Haworth as the extraction source, firstly, by changing the growth conditions of microorganisms, more trehalose is accumulated in the body, and then the trehalose is extracted by appropriate methods. Microbial extraction of trehalose has long production cycle, low extraction rate and high cost, making it difficult to achieve large-scale industrial production.

2. Microbial fermentation method

Trehalose Haworth is produced by microbial fermentation, and then extracted and purified from the fermentation broth. The key is to select high-yielding trehalose strains through mutagenesis, cell fusion and gene recombination. Ajinomoto Co., Ltd. of Japan has realized industrialized production of trehalose by in vitro culture of amino acid-producing bacteria, but this method has a low conversion rate and many by-products.

3. Enzymatic synthesis

Using glucose, maltose, and starch as substrates, three methods are used, but there are problems such as high energy consumption and unstable phosphorylase, so it is difficult to realize industrial production.

4. Genetic engineering method

The gene of Trehalose Haworth synthase is introduced into plants or microorganisms, and the engineered microorganisms or transgenic plants can be used to produce trehalose.

5. Chemical synthesis

2,3,4,6-Tetraacetylglucose and 3,4,6-triacetyl-1,2-anhydro-D-glucose produce ethylene oxide addition. The disadvantage of this method for preparing Trehalose Haworth is that the yield is low and the separation is difficult, and it is still in the research stage.

Trehalose Haworth Preparation

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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