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Trans-Ferulic Acid CAS 537-98-4

Molecular Formula: C10H10O4

Formula Weight: 194.18

ZSpharmac: Trans-Ferulic Acid Raw Material Supplier

Product Name: Trans-Ferulic Acid
CAS No: 537-98-4
Purity: 99%

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Basic Info

Product Name:Trans-Ferulic Acid
Other Names:Ferulic acid
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Light Yellow Powder
EINECS No.:208-679-7
Storage:Store Below +30°C
Provide:Trans-Ferulic Acid MSDS;
Trans-Ferulic Acid COA

What is Trans-Ferulic Acid?

Ferulic Acid, also known as 4-hydroxy-3-methoxycinnamic acid, is a derivative of cinnamic acid, specifically 3-phenyl-2-acrylic acid. It exists in two forms: cis and trans. The cis form appears as a yellow oil, while the trans form is observed as square or fiber crystals. Its melting point is 174°C. Ferulic Acid is soluble in hot water, ethanol, and ethyl acetate. It has slight solubility in ether but is insoluble in benzene and petroleum ether. It is commonly referred to as trans-ferulic acid.

Trans-Ferulic Acid Property

Melting point 168-172 °C(lit.)
Boiling point 250.62°C (rough estimate)
density 1.316(20.0000℃)
refractive index 1.5030 (estimate)
Fp 150℃
storage temp. Store below +30°C.
solubility DMSO (Slightly), Methanol (Slightly)
form powder
color slightly yellow
Water Solubility Soluble in alcohol and hot water.


Trans-Ferulic Acid Uses

Antioxidants, antithrombotics, hypolipidemic agents, and anti-atherosclerotic treatments are effective for managing coronary heart disease, angina pectoris, and other conditions caused by atherosclerosis. Additionally, they possess antibacterial and anti-inflammatory properties, contribute to cancer prevention by inhibiting mutations, regulate the immune system, enhance sperm vitality and motility in humans, and eliminate nitrite. These beneficial effects have led to their approval as food additives in the United States and Japan. Consequently, they are extensively utilized in the medical field (e.g., Xinxuekang), food industry (e.g., Taitai oral liquid, sports nutrition, preservatives, antioxidants), and cosmetics industry (e.g., sunscreen).

Trans-Ferulic Acid Biological Activity

(E)-Ferulicacid is an isomer of ferulic acid, an aromatic compound that is abundant in plant cell walls. (E)-Ferulicacid causes the phosphorylation of β-catenin, leading to proteasomal degradation, increasing the expression of the pro-apoptotic factor Bax and reducing the expression of the pro-survival factor Survivin. (E)-Ferulicacid can effectively remove reactive oxygen species (ROS) and inhibit lipid peroxidation. (E)-Ferulicacid exerts anti-proliferative and anti-migration effects in human lung cancer cell line H1299.

Trans-Ferulic Acid Organic Synthesis Method

The production methods of Trans-Ferulic Acid include chemical synthesis and alkaline hydrolysis. The chemical synthesis method uses vanillic aldehyde and malonic acid as raw materials, anhydrous pyridine as the solvent, and piperidine as the catalyst, and is obtained through a condensation reaction. However, the ferulic acid obtained by this method is a mixture of cis and trans ferulic acid, and the reaction time is long (up to 3 weeks), the solvent consumption is large, and the yield is also very low. Currently, the production of commercialized trans-ferulic acid relies entirely on extracting oryzanol from rice bran oil and then obtaining it through alkaline hydrolysis. The content of oryzanol in rice bran oil is low, accounting for only 1.5% to 2.8% of rice bran oil. This is also the main reason why the current production cost of trans-ferulic acid is high and expensive.

About Products:
If you need the cosmetic raw material Trans-Ferulic Acid, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced Trans-Ferulic Acid manufacturer and supplier, our company, ZSpharmac will provide Trans-Ferulic Acid raw materials to customers around the world for a long time.
Over the years, the company has adhered to the spirit of “integrity management, strict quality control, and customer first” and has won unanimous praise from customers at home and abroad.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Trans-Ferulic Acid Quotation