Zhishang Chemical

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Thioctic CAS 62-46-4

Molecular Formula: C8H14O2S2

Formula Weight: 206.33

ZSpharmac: Thioctic Supplement

Product Name: Thioctic
CAS No: 62-46-4
Purity: 99%

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Basic Info

Product Name:Thioctic
Other Names:Lipoic Acid
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Yellow Powder
EINECS No.:200-534-6
Provide:Thioctic MSDS
Thioctic COA

What is Thioctic?

Thioctic is an anti-oxidant that surpasses vitamins A, C, as well as E and gets rid of totally free radicals that accelerate aging as well as cause disease. At the same time, lipoic acid likewise has several valuable results on the body. It is also a reliable antioxidant and also heavy metal chelator. The body can synthesize an ideal amount of Thioctic, but when it remains in a state of stress or disease, its synthesis can not meet the need.Like lots of important materials in the body, Thioctic levels decrease with age.

Among the many anti-oxidants, Thioctic has its distinct versatility.It can not just stand up to a selection of cost-free radicals such as oxide anions, hydroxide ions, singlet oxygen as well as hydrogen peroxide, but also chelate (integrate and incorporate with steel ions (such as iron, copper, cadmium, lead, mercury as well as various other metal ions) neutralization), which militarizes the generation of complimentary radicals. An additional crucial duty of Thioctic is to decrease blood sugar. Because of its antioxidant, steel chelating, and hypoglycemic homes, lipoic acid can avoid hyperglycemia as well as cross-linking (high blood sugar as well as cross-linking are very important causes of aging as well as are very closely related to wrinkle development).

Thioctic Properties

Melting point 48-52 °C(lit.)
Boiling point 315.2°C (rough estimate)
density 1.2888 (rough estimate)
refractive index 1.5200 (estimate)
Fp >230 °F
solubility Very slightly soluble in water, very soluble in dimethylformamide, freely soluble in methanol.


Thioctic Uses

  1. Thioctic has powerful antioxidant capability, its anti-free radical capacity is 400 times far better than that of VC as well as VE, it can eliminate active oxygen components that trigger skin aging, as well as the molecule is smaller than VE, and it is both water-soluble It is lipophilic and also fat-soluble, so it is quickly soaked up by the skin. Thioctic not only has solid resistance to long-lasting oxidative damages, but likewise can successfully fix the extra serious mobile oxidative damages that can not be fixed by VC as well as VE.
    Researches have actually revealed that Thioctic can be exchanged dihydrolipoic acid in the body, both of which have strong antioxidant residential or commercial properties and also work synergistically in the body. At the same time, the molecular weight of Thioctic is in between ascorbic acid and also tocopherol, as well as it has the amphiphilicity of water and lipids, which can put in a thorough antioxidant impact in the body, as well as is called “global anti-oxidant”.
    The antioxidant efficiency of Thioctic is mostly mirrored in three elements:
    1. Direct scavenging of cost-free radicals, lipoic acid can straight feed on totally free radicals such as hydroxyl radicals and singlet oxygen after entering cells;
    2. Prevent metal-induced oxidation, Thioctic has the result of chelating metal ions, thereby reducing the peroxidation of macromolecules such as lipids caused by steel ions;
    3. Advertise the recovery of various other antioxidant elements. Thioctic can restore the capability of endogenous anti-oxidants such as vitamin E as well as glutathione in the body, therefore boosting the overall antioxidant ability 。
  2. Thioctic can restore the capability of endogenous anti-oxidants such as vitamin E as well as glutathione in the body, therefore boosting the overall antioxidant ability 。.
    Thioctic is a chelating agent for numerous steels. It functions synergistically with dihydro-thioctic to chelate metal ions such as cadmium, nickel, copper, lead, as well as ferric iron to minimize the toxicity of metals to the liver. Therefore, it was additionally utilized as gastrointestinal disorder in the early days. Or an antidote for steel poisoning. At the same time, the synergistic result of Thioctic and other antioxidants in the body can lower the damage of complimentary radicals to liver cells, minimize inflammation and also preserve liver feature. Some researches have mentioned that Thioctic can get rid of the fat buildup caused by non-alcoholic fatty liver and also decrease the problem on the liver.
  3. Anti-glycation is a preferred new idea of health.Its function is to decrease the damage to cells triggered by the response final result of reducing sugars as well as healthy proteins in the body under non-enzymatic problems, one of the most regular of which is to minimize the damages to skin collagen. Collagen restores at a slower price than various other healthy proteins as well as is a lot more susceptible to glycation, causing plain skin as well as lowered flexibility. In the anti-glycation market, anti-oxidants are the outright major pressure, which can efficiently resist the effect of glycation on the skin, while Thioctic has the dual safety effects of blood glucose stablizing as well as stopping the combination of sugar as well as collagen in anti-glycation. It is an anti-sugar beauty item One of the crucial development directions. At the same time, Thioctic’s activation of vitamin C can offset the decreased degrees as a result of resistance to UV rays, enhancing the skin’s capacity to stand up to outside stimulations.

Thioctic Preparation

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Thioctic Quotation