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Thioacetic Acid CAS 507-09-5

Molecular Formula: C2H4OS

Formula Weight: 76.12

ZSpharmac: Thioacetic Acid Supplier

Product Name: Thioacetic Acid
CAS No: 507-09-5
Purity: 99%

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Basic Info

Product Name:Thioacetic Acid
Other Names:Thioacetic Acid, 97.5%
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Clear Colorless to Pale Yellow Liquid
EINECS No.:208-063-8
Storage:Store Below +30°C.
Provide:Thioacetic Acid MSDS;
Thioacetic Acid COA

What is Thioacetic Acid?

Thioacetic acid is an acid containing mercapto groups, likewise called thioacetic acid, ethyl thiol acid, and also ethyl sulfuric acid. Yellow fuming liquid with unpleasant poignant odor, active chemical residential or commercial properties and solid reactivity, it can react with unsaturated aliphatic hydrocarbons as well as alcohols to prepare mercaptans.
React with ethylene oxide to prepare acetylthioethanol.

Thioacetic Acid Property

Melting point 

-17 °C

Boiling point 

97 °C


1.065 g/mL at 25 °C(lit.)

vapor pressure 

1 hPa (20 °C)

refractive index 

n20/D 1.465(lit.)


52 °F

storage temp. 

Store below +30°C.


27g/l (slow decomposition)




3.33(at 25℃)


Clear colorless to pale yellow


1.8 (100g/l, H2O, 20℃)Hydrolysis

Water Solubility 

27 g/L (15 ºC) (hydrolyse)



Thioacetic Acid Uses

  1. Thioacetic acid can change hydrogen sulfide in the laboratory, examination cobalt and lead, figure out molybdenum, synthesize thioaldehyde as well as thione, establish esterase in histochemistry, as well as be utilized as tear gas.
  2. Thioacetic acid is an acetylthiolating agent and mercaptoylating representative in organic synthesis. It is mostly used for the synthesis of lipoic acid, cystine, and mercaptocarboxylic acids, and is additionally used as a modifier and also antidote for hormones, and for modification of cephalosporins. Synthesis of stabilizers and also fungicides, polymer modifiers as well as additives. Made use of in reagents, flavors as well as fragrances, cosmetics, synthesis of captopril, etc.
  3. Thioacetic acid is made use of as an intermediate in medication, taste and also fragrance.
  4. Thioacetic acid is used as a chemical reagent, precipitant and also stimulant.

Thioacetic Acid-Mediated Synthesis of N-Protected Aminothioacids

Thioacids have actually just lately obtained power as a result of their multifunctional level of sensitivity. The sensitivity of thioacids has actually been extensively taken a look at in critical amide/peptide bond formation. Thioacids are typically manufactured by responding active carboxylic acids such as acid chlorides as well as energetic esters with Na 2 S, H 2 S or NaSH. We sought to have a look at whether the multifunctional sensitivity of thioacids could be tuned to change carboxylic acids to the comparable thioacids in the presence of NaSH. Below, we report Thioacetic acid as well as also NaSH-mediated synthesis of N-protected aminothioacids from the matching N-protected amino acids, oxidative dimerization of thioacids, crystal conformations of thioacid oxidative dimers, as well as making use of thioacids in addition to oxidized dimers in peptide synthesis. Our outcomes show that peptides can be manufactured without making use of conventional combining representatives.

Preparation of Thioacetic acid

Four methods for preparing thioacetic acid in the laboratory: 1. React acetic acid with phosphorus pentasulfide at 91°C, and further refine it by vacuum distillation. Can be made. 5CH3COOH+P2S5→CH3COSHC2H4OS+P2O52, acetyl chloride reacts with hydrogen sulfide, neutralizes with dilute lye, and refines by rectification. Can be made. 3. The reaction of acetic anhydride and hydrogen sulfide can produce the finished product of thioacetic acid, and at the same time by-product acetic acid. 4. It can be directly prepared by reacting ketene with hydrogen sulfide.

About That Product:
If you need Thioacetic Acid, a cosmetic raw material, please contact our service staff directly, and we will provide you with high-quality products at the best price.
As an experienced Thioacetic Acid manufacturer and supplier, ZSpharmac will provide Thioacetic Acid raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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