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Theaflavin Supplement CAS 4670-05-7

Molecular Formula: C29H24O12

Formula Weight: 564.49

ZSpharmac: Theaflavin Supplement Supplier

Product Name: Theaflavin Supplement
CAS No: 4670-05-7
Purity: 99%

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Basic Info

Product Name:Theaflavin Supplement
Other Names:Theaflavin
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Red to Very Dark Red Neat
Provide:Theaflavin Supplement MSDS;
Theaflavin Supplement COA

What is Theaflavin Supplement?

Theaflavin is an important top quality component and additionally functional part in black tea. It has numerous organic activities and medicinal impacts such as decreasing blood fat, lowering hypertension, anti-oxidation, anti-radiation, antibacterial, as well as also anti-cancer. It is referred to as “soft gold in tea”, the web content of theaflavins in black tea is only 0.5%-2.0%.
Theaflavins are a basic term for a class of substances that are soluble in ethyl acetate in addition to have really benzotropolone developed by the oxidation of polyphenols. Theaflavins have 12 elements, consisting of theaflavins (TF), theaflavins-3-gallate (TFMG), theaflavins-3,3′-digallate (TFdiG) and likewise theaflavins -3′-gallate (TFM’G) is the 4 important theaflavins (see the picture above for the chemical framework). The cleansed product of theaflavin is orange-yellow needle crystal, melting point 237-240 ° C, swiftly soluble in water, methanol, ethanol, acetone, n-butanol as well as ethyl acetate, barely soluble in ether, insoluble in chloroform as well as additionally benzene. Theaflavin option is intense orange, as well as likewise the liquid option is weakly acidic, with a pH of concerning 5.7. The color is not influenced by the pH of the tea soup significance, however it has a tendency to auto-oxidize in alkaline service, as well as likewise it is strengthened with the rise of pH.

Theaflavin Supplement Property

Melting point 237-240 °C (decomp)(Solv: water (7732-18-5))
Boiling point 1079.6±65.0 °C(Predicted)
density 1.777±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO (Slightly), Methanol (Slightly)
form neat
color Red to Very Dark Red


Theaflavin Supplement Uses

Application of Theaflavin Supplement in skin care preparations and skin care items having theaflavin.
Theaflavin Supplement can hinder the spreading of human nasopharyngeal carcinoma CNE2 cells as well as cause their apoptosis in a time- and concentration-dependent manner. The mechanism of action might be associated with controling the expression of cell proliferation and apoptosis genetics.

Theaflavin Supplement can minimize lotion uric acid in mice with hyperuricemia. Its effect of reducing product uric acid is connected to the restraint of xanthine oxidase task and the law of related anion transporter mRNA and also protein expression levels.

Theaflavins can boost the sensitivity of cervical cancer cells to cisplatin, as well as the mechanism may be associated with enhancing the expression of apoptosis-related proteins Cleaved Caspase 3, Cleaved Caspase 9, and PARP and also preventing NF-κB signaling pathway-related proteins p-IκBα, p-NF -κB is associated with the expression of p-Akt.

Theaflavin Supplement can effectively delay the inflammatory deterioration process of rat chondrocytes by enhancing the task of chondrocyte synthesis variables, weakening the activity of decay factors and hindering cell inflammation, and also has a particular protective result on inflammatory chondrocytes.

Theaflavin Supplement Extraction Method

Detection of Theaflavin Supplement

Wu Hanyin and others established a high performance fluid chromatography (HPLC) approach for the decision of theaflavins in milk tea beverages. Methods Milk tea samples were precipitated with 0.1% acetic acid ethanol, centrifuged at 5000 r/min for 5 min, and the supernatant was considered detection. Using 0.5% acetic acid (A) and acetonitrile (B) as the mobile phase for gradient elution, the diode selection detector was made use of to check at 280 nm, the flow price was 1.5 mL/min, the column temperature level was 40 ° C, and the external standard approach was made use of for metrology. Results The method could achieve the separation and also discovery of four target substances, the healings of the 4 theaflavins remained in the range of 89.06%-96.51%, and the family member standard deviation was less than 5% (n=5). Verdict The approach has the advantages of brief pretreatment time, straightforward procedure, great security as well as high accuracy, as well as can be used for the determination of theaflavins in milk tea beverages.

About Products:
If you need Theaflavin Supplement, the cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced Theaflavin Supplement manufacturer and supplier, ZSpharmac will provide Theaflavin Supplement raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Theaflavin Supplement Quotation