Zhishang Chemical

Welcome to Zhishang Chemical      +86-176 5311 3209     Simon@sdzschem.com

Zhishang Chemical
Close this search box.

Span 80 CAS 1338-43-8

Molecular Formula: C24H44O6

Formula Weight: 428.6

ZSpharmac: Span 80 Raw Material Supplier

Product Name: Span 80
CAS No: 1338-43-8
Purity: 99%

Navigation Bar

Basic Info

Product Name:Span 80
Other Names:Sorbitan Monooleate
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Yellow Viscous Liquid
EINECS No.:215-665-4
Storage:Store Below +30°C.
Provide:Span 80 MSDS;
Span 80 COA

What is Span 80?

Period 80 emulsifier, whose scientific name is sorbitan monooleate, is a polyol-type nonionic surfactant and is one of the most generally made use of water-in-oil outstanding emulsifier in existing manufacturing. Period 80 emulsifier is dehydrated and etherified under sorbitol acid catalytic conditions to create anhydrous sorbitan, and after that esterified with oleic acid in a reactor at heats of around 200 to 210 ° C under alkali catalyzed problems. Because of different synthesis processes, the top quality of the produced Period 80 is different, and the yield price is also different. Currently, when producing the emulsifier Span 80, it is impacted by the proportion of basic materials, causing sorbitol sugar deposit and carbon dioxide generated by the response. There is more slag and the productivity is reduced, which reduces the manufacturing performance.

Span 80 Property

Boiling point 463.43°C (rough estimate)
density 0.986 g/mL at 25 °C(lit.)
vapor pressure <1.4 hPa (20 °C)
refractive index n20/D 1.48(lit.)
Fp >230 °F
storage temp. Store below +30°C.
solubility Practically insoluble but dispersible in water, soluble in fatty oils producing a hazy solution, miscible with alcohol.
form Viscous Liquid
color Yellow
Specific Gravity0.986
Odorat 100.00 %. fatty oily waxy
Odor Typefatty
Water Solubility Soluble in ethanol at 50mg/mlMiscible with water, ethanol, isopropanol and ether. Insoluble in acetone.


Span80 Application

  1. Preparation of polymerizable emulsifiers
    47.1 g of Period 80, 7.2 g of acrylic acid, 100mL of ethyl acetate as the solvent, 0.1 g of hydroquinone as the polymerization prevention, 3.0 g of p-toluenesulfonic acid as the driver, mix and reflux at 80 ° C for 15h, after the reaction is completed Filter the reaction remedy while warm, wash with 1% sodium hydroxide option up until the pH value of the water phase is about 6, then wash with saturated sodium chloride solution until the pH value of the water stage has to do with 7, and completely dry the oil phase with anhydrous magnesium sulfate overnight., filter to separate the oil phase, and boil down the solvent under reduced pressure to acquire acryloyloxyethane 80.
  2. Preparation of spherical water-absorbent material
    Evaluate 15 kilograms of acrylic acid, add it to a stainless steel neutralization pot with a coat and a stirrer, fill up the jacket with distributing water, gradually add 27% ammonia water (the antacid web content is 3.25 kgs of NH3), and control the neutralization temperature level at 20 ° C, PH=6 ~ 7 at this time, after that include 2.5 kg of acrylamide and 0.005 kg of cross-linking representative N, N,-methylene bisacrylamide. Mix and dissolve to form a water phase. Begin the shear emulsification mixer, include 13.5 kg of diffusion medium kerosene, 6 kg of Period 80, and 0.3 kg of monoglyceride. Mix and mix and heat to 60-65 ° C to liquify. Then add the water phase to the oil phase and stir. The reverse phase suspension will be gotten after 1 to 2 hours. After putting the reversed-phase suspension into a container, control the temperature level of the reversed-phase suspension at 5 ° C and place it in a 60Co-γ ray area with a dosage price of 0.05 KGy/h and a dosage of 2KGy. No requirement to stir, and let it stand in the radiation field. In the lighting area, it is irradiated and permitted to mean polymerization. After the response is finished, a round water-absorbent material is obtained. The oil stage is separated and dried in an infrared dryer to get the item.

What is the Difference Between Tween 80 and Span 80?

1. Various applications in the food market
1. Tween 80: used as an emulsifier in the food market, utilized in the production of drinks, toffee, gelato, bread, breads, malted milk, margarine, scrumptious chocolate, etc 2. Period 80: This item is mostly made use of as a solubilizer or emulsifier for shots and oral liquids; a dispersant for pills and an emulsifier in the food market.

2. Different scope of application
1. Tween 80: It is suitable for dark and light things of pet and vegetable oils and artificial carboxylic acid ester surfactants. It is not suitable for things that are testing to saponify and have mineral acids.
2. Duration 80: made use of in W/O latex dynamites, nylon and viscose cord oil, and has an excellent smoothing result on fibers. Utilized for emulsification of equipment, coatings, chemicals, and nitroglycerins. It is taken advantage of as an emulsifier in heavy mud for oil drilling and as an emulsifier in food and cosmetics production.

3. Different usage criteria
1. Tween 80: Steam the ethanol service of potassium hydroxide under reflux and later on titrate the excess potassium hydroxide with a common hydrochloric acid choice.
Span 80: As a movie anti-fog and trickling agent, it has good first and low-temperature anti-fogging and flowing buildings. The dose in PVC is 1-1.5%, and the dose in polyolefin is 0.5-0.7%.

Span80 Preparation

(1) Warm 400kg sorbitol solution to 130 ~ 140 ℃, get rid of totally free water, and create sorbitol;
( 2) An etherification reaction occurs in between sorbitol and the catalyst at 130-150 ° C under vacuum cleaner. The reaction time is 3 hours to create anhydrous sorbitol. The stimulant made use of is phosphoric acid, and the amount of phosphoric acid included is sorbitol. 0.5% of mass;

( 3) Warm 740kg of oleic acid to 100-180 ° C for refining to generate necessary oil acid;
( 4) Put the necessary oil acid and sorbitan anhydride into the reaction pot at an acid-to-alcohol molar proportion of 450:740, add an alkaline driver, and keep the response at 180 to 190 ° C for 2 hours, and afterwards maintain it at a continuous temperature level of 210 to 220 ° C. The esterification response takes 3 hours. The alkaline stimulant made use of is salt hydroxide. The amount of alkaline driver added is 0.3% of the total mass of sorbitan anhydride and crucial oil acid;

( 5) Accomplish vacuum dehydration and esterification of the materials after the above response for 1.5 hours to obtain an unrefined product;

( 6) Move the crude product right into the rainfall pot, and accomplish air conditioning and rainfall under heat conservation conditions. The rainfall time is 12 hours and the temperature level is 100-120 ° C. After the rainfall is completed, the sediment is released from all-time low of the precipitation tank. The remainder is the emulsifier Span 80 Ended up item.

About Products:
If you need the cosmetic raw material Span80, please contact our service staff directly, we will provide you with high-quality products at the best price.
Our company, as an experienced Span80 manufacturer and supplier, ZSpharmac will provide Span80 raw materials to customers around the world for a long time.
Over the years, the company has adhered to the spirit of “integrity management, strict quality control, and customer first” and has won unanimous praise from customers at home and abroad.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Span 80 Quotation