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Sorbitan Trioleate CAS 26266-58-0

Molecular Formula: C60H108O8

Formula Weight: 957.49

ZSpharmac: Sorbitan Trioleate Supplier

Product Name: Sorbitan Trioleate
CAS No: 26266-58-0
Purity: 99%

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Basic Info

Product Name:Sorbitan Trioleate
Other Names:Span 85
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Colourless to Pale Yellow Oil
EINECS No.:247-569-3
Storage:Store Below +30°C.
Provide:Sorbitan Trioleate MSDS;
Sorbitan Trioleate COA

What is Sorbitan Trioleate?

Sorbitan Trioleate is a synthetic non-ionic emulsifier created by partial esterification of sorbitol or sorbitan with food-grade palmitic acid. It is light velvety yellow to brownish-yellow great grains, flakes or hard waxy particles, with a soft oily scent and sugar sweet taste. Span-85 is not a single material, yet a mix of various similar frameworks, with sorbitol intoxicated trioleic acid phenol as the text. It has decreased thickness as well as also the smallest HLB well worth, so it has the greatest lipophilicity. It is a remarkable water-in-oil (w/O) emulsifier and a sustaining emulsifier of O/w kind.

Sorbitan Trioleate Property

Melting point -23°C(lit.)
density 0.94 g/mL at 20 °C
vapor pressure <1.4 hPa (20 °C)
refractive index n20/D 1.476(lit.)
Fp >230 °F
storage temp. Store below +30°C.
solubility chloroform: soluble50mg/mL, clear, faintly to light yellow
form Oil
color Colourless to Pale Yellow


Sorbitan Trioleate Application

Period emulsifiers can be used as emulsifiers in the prep work of creams, solutions as well as lotions. When used alone, they can prepare stable water-in-oil solutions or microemulsions; if utilized in combination with different percentages of hydrophilic emulsifier Tween, numerous water-in-oil and oil-in-water solutions or creams can be prepared; it can likewise be made use of as a solubilizer, moistening representative, dispersant, putting on hold representative, and so on. It can be utilized to prepare inhalants, intramuscular injections, oral solutions, ocular preparations, topical prep work as well as vaginal preparations. Medicinal Sorbitan Trioleate is an outstanding non-ionic surfactant, which can be utilized as emulsifier, solubilizer, putting on hold agent, moisturizer, and so on. It is commonly used in the pharmaceutical market.

Sorbitan Trioleate has actually been utilized as emulsifier, solubilizer, suspending representative as well as lubricant in aerosol, lotion, shot, lotion and also other dosage forms in China. The literature points out that surfactants can serve as protective agents and stabilizers in suspensions, as well as nonionic surfactants with an HLB value of less than 10 are the most effective. Span-85 is one of the most commonly utilized fluid that can liquify or distribute in the liquid stage. The concentration is 0.25 ~ 1% of the total weight, and it is also useful to more than 5%. In a British license for the manufacture of medical powder aerosols, it is pointed out that the suspension powder is insoluble as well as well dispersed in the mix of liquefied propellant Liu and fluid non-ionic surfactants. Amongst the 38 prescriptions provided, there are 36 made use of the Period collection, 33 of which made use of Span-85 (prescriptions containing primary medicines such as hydrocortisone, phenylephrine, and so on). adrenaline, guaiacol glycerin), salt cromoglycate, cromoglycate, hexylamine, ethoxycoumarin, triple bacterin and also various other aerosol formulations. Pharmaceutical manufacturing facilities in Shanghai, Chongqing, Wuxi as well as various other locations additionally extensively Utilized as a valve system lube, the frictional resistance is little, as well as the springtime recovers rapidly, which is far better than that of mineral oil. After use, there is much less recurring amount in the valve, and the odor is little. It does not influence the shade of the aerosol as well as improves the amount after spraying. After comparison, Sorbitan Trioleate is superior to Span-80 (both have particular anti-rust effects on springs). Wuxi Drug No. 1 Factory uses Span-85 as a solubilizer for shed aerosol as well as shed liniment to raise the solubility of chlorhexidine acetate in sesame oil, which is much better than Span-80 comparative, with excellent solubilization efficiency as well as low thickness. The finished item is transparent, very easy to filter and use.

The solution beads made by Sorbitan Trioleate, 95% of the oil droplet dimension is below 5μ. Some fat-soluble vitamins, such as A, D, and also E, are frequently made right into oil injections. If you wish to prepare water-based injections or water-based suspension injections, you have to include a dispersant. For instance, Span-85, it has the effect of solubilizing micelles for the main medication. Vidin gelatinous calcium shots in Jiangsu, Guangdong, and also Zhejiang consist of Span-85 0.22% as well as Tween-80 0.88%. For the security examination, after 4000rPm for 15 mins, there is no delamination. Sorbitan Trioleate can boost the solubility as well as release of medications in ointment bases and lower thickness. It is also made use of in tablet covering solutions in foreign nations, and has the functions of anti-humidity and so on. Span series have actually been used as preservative in Japan and also other countries, used in ice cream, bread, cakes, delicious chocolate, sugar, and so on as emulsifiers and also dispersants, as stabilizers and putting on hold agents for emulsified foods, and as consumer lathering representative.

Sorbitan Trioleate Production Method

Put 1 mol of sorbitol right into the response kettle, vacuumize and also dry out, place the preheated polished oleic acid right into the pot, the amount of oleic acid added is 3 mol, and also after that consist of an appropriate amount of salt hydroxide as a chauffeur.Then the temperature was gradually elevated to regarding 210 ° C under vacuum cleaner, as well as the temperature level was kept for 8 hours. Testing to determine the acid value is 14-15 mgKOH/g and the esterification reaction mores than. Stand for stratification, discard the lower layer liquid, placed the top layer liquid into the decolorization kettle, decolorize with hydrogen peroxide, dry out under reduced stress, after dehydration is completed, the discharge packaging is Sorbitan Trioleate.

About Products:
If you need Sorbitan Trioleate as a cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced Sorbitan Trioleate manufacturer and supplier, ZSpharmac will provide Sorbitan Trioleate raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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