Zhishang Chemical

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Zhishang Chemical

Something Bakuchiol CAS 10309-37-2

Molecular Formula: C18H24O

Formula Weight: 256.38

ZSpharmac: Something Bakuchiol Supplement

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Product Name: Something Bakuchiol
CAS No: 10309-37-2
Purity: 99%

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Basic Info

Product Name:Something Bakuchiol
Other Names:4-(3,7-DIMETHYL-3-VINYL-OCTA-1,6-DIENYL)-PHENOL
CAS:10309-37-2
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Oil neat
EINECS No:0
Storage:Inert Atmosphere,Store in Freezer, Under -20°C
Provide:Something Bakuchiol MSDS;
Something Bakuchiol COA

What is Something Bakuchiol?

Something Bakuchiol is an organic natural ingredient discovered from the seeds as well as fallen leaves of a plant called Psoralea (Psoraleacorylifolia), which stems from India as well as plays a crucial role in Ayurvedic organic medication. There are also several Chinese medicine-related elements that are extensively utilized in China. Something Bakuchiol is a powerful anti-oxidant that visibly decreases skin direct exposure to the environment as well as has a calming effect. On top of that, it can also smooth great lines and also wrinkles. Integrating the above advantages, bakuchiol has shown up in increasingly more skin treatment products in the last few years. The most recent study shows that topical use on the skin is effective for all skin kinds. Each kind has special benefits.

Something Bakuchiol Properties:

Boiling point 391℃
density 0.963
refractive index 1.4500 (estimate)
Fp 177℃
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml)
pka10.10±0.26(Predicted)
form neat
color Oil

 

Something Bakuchiol Uses

  1. Something Bakuchiol has no photosensitivity as well as is a great deal on the skin. It is a reasonably new active component in skin treatment products in recent times. Based on its oil control, anti-oxidant, antibacterial as well as anti-inflammatory results, it is the gospel of oily acne skin. One more essential impact of bakuchiol is anti-aging. CTFA uses bakuchiol as a cosmetic raw material, which is included in the 2000 edition of the “International Standard Chinese Name Catalog of Cosmetic Raw Materials” by the China Fragrance Association.
  2. Something Bakuchiol is used for assay/identification/pharmacological experiments and other pharmacological effects: antibacterial effect, anti-implantation and estrogen-like effect.
  3. Something Bakuchiol has hypoglycemic and hypolipidemic, anti-inflammatory, antibacterial, antioxidant and hepatoprotective, anticancer, antidepressant, estrogen-like effects.
  4. Something Bakuchiol can be used to manufacture nephritis model. Kernel has cytotoxic activity and is an effective ingredient for clinical treatment of corns.

What is the Relationship Between Something Bakuchiol and Retinol?

It looks a bit like, probably so, there are some functional similarities between the two.

But they are two completely different ingredients.

In our upcoming introduction to Wildcrafted’s new essence, founder Nicole mentioned a clinical trial conducted abroad.

It’s about retinol versus Something Bakuchiol.

The two ingredients were used on two groups of people for 12 weeks to compare the skin’s wrinkles, pigmentation, elasticity, firmness and overall photodamage, and found that there were significant improvements, while Something Bakuchiol had a more irritating effect on the skin. Small.

It is clinically proven to reduce many signs of aging without the irritation and instability issues inherent in retinol.

So it should be a more ideal ingredient than retinol for many sensitive skins. In addition to excellent anti-aging effects, it also has a good set of solutions for acne problems.

Therefore, in niche organic skin care products, more and more products add it, which is also very understandable! Plant-derived Something Bakuchiol, which is a potential antibacterial substance, has better antioxidant and anti-inflammatory effects than retinol, and is a long-lasting player for oily and acne-prone skin.

For example, the squalene contained in the skin is easily oxidized under ultraviolet radiation, which will lead to skin keratinization, keratinocytes will block pores, and then acne will be formed to block pores.

In this regard, Something Bakuchiol acts as a fat-dissolving antioxidant stronger than vitamin E, which can protect skin sebum from oxidation and prevent hair follicles from clogging the skin.

Also, retinol is not recommended for pregnant women, but Something Bakuchiol does not have this warning.

Replacing Retinol, How Far is Something Bakuchiol on The Way?

The Mintel Global New Products Database (GNPD) predicted two years ago that Something Bakuchiol would enter the mainstream skin care products represented by botanical extract formula products.

Something Bakuchiol is a monoterpene extracted from the Psoralea plant.

It is widely used in traditional medicine in some Asian countries, especially in Ayurvedic medicine in India, to treat various diseases.

In the marketing of beauty products containing Something Bakuchiol, it is often suggested that it is similar to retinol, but this is not the case. Mary Sheu MD, assistant professor of dermatology at the Johns Hopkins University School of Medicine, said: “Despite similar uses in cosmetics, Something Bakuchiol is completely different in molecular structure from retinol.

Retinol is one of the main forms of vitamin A that the body absorbs from animal products. This means that over-the-counter retinol products may come from animals, which is not the case for Something Bakuchiol products. However, as a new drug, there are few clinical studies on its efficacy and side effects. But as an emerging skin care ingredient, especially in the current era of clean skin care, brands are racing to discover the next natural, safe and effective key ingredient, and Something Bakuchiol has a bright market prospect.

Two recent clinical studies have obtained data on the anti-aging efficacy of Something Bakuchiol and its comparison with retinol.

In the first study, published in the International Journal of Cosmetic Science in 2014, researchers used artificial skin and collagen cells to test the anti-aging benefits of Something Bakuchiol. The results show that Something Bakuchiol has properties that affect gene expression and regulate collagen very similar to retinol in artificial skin and disembodied cells. To see how bakuchiol performed in real life, they asked 16 participants to use a 0.5% bakuchiol product twice a day for 12 weeks. Compared with no use, participants improved in every measure, including skin fine lines and wrinkles, roughness, dryness, and elasticity. In addition, the participants did not experience common retinol side effects such as irritation, dryness and peeling.

In 2018, the British Academy of Dermatology published a further clinical study. In a 12-week, double-blind clinical trial, researchers compared the efficacy of Something Bakuchiol with retinol. In this study, 44 participants used a 0.5% bakuchiol product twice daily or a 0.5% retinol product once daily and had their skin condition assessed by a dermatologist. Compared with before the experiment, the two groups of subjects showed improvement in pigmentation, wrinkles and skin redness, and the effect of the two groups was not statistically significant, indicating that the effect of bakuchiol twice a day was better than that of using bakuchiol once a day. Retinol has the same effect. At the same time, the Something Bakuchiol group reported less flaky skin and peeling than the retinol group.
Other studies have looked at combining Something Bakuchiol with other anti-aging ingredients (such as antioxidants), but only these two clinical studies provide the best and only data on Something Bakuchiol as a single ingredient.

Taken together, these studies suggest that Something Bakuchiol may be as effective as retinol, and possibly milder.

In addition, Olga Bunimovic, an assistant professor at the University of Pittsburgh Medical Center and a dermatologist, said: “At the moment, we only know the relationship between Something Bakuchiol and retinol, but not the relationship between it and other retinoids such as retinoids. relation.

Last year, dermatologist Zoe Derelos conducted a clinical evaluation of a natural bakuchiol anti-aging moisturizer for sensitive skin. Studies have shown that bakuchiol-based anti-aging moisturizers are well tolerated and effective in individuals with sensitive skin.

Need to focus on the optimal concentration, formulation application and mechanism of action

There is a consensus among dermatologists on possible ways to slow down skin aging.

“Retinol is our holy grail,” said dermatologist Mona Gohara, an associate clinical professor of dermatology at Yale University. “Retinol is a derivative of vitamin A that increases collagen synthesis. It is known for reducing collagen breakdown. Unfortunately, it also has side effects such as peeling, dryness or redness. It is FDA listed as a Class C drug, and it has potential risks for pregnant women.”

Something Bakuchiol is gaining popularity in the skincare world as a plant-derived retinol alternative. “It has the benefits of vitamin A without the side effects,” Gohara said. “Not only is it clinically comparable to retinol, it’s not irritating, and bakuchiol is safe for most skin types.” Plus, unlike retinol, which breaks down in sunlight, bakuchiol can be used during the day, an advantage for newer products from brand

s like Herbivore Botanicals and Beautycounter.

Something Bakuchiol was first commercially available as a topical drug in 2007, when it was introduced to the market under the name Sytenol A by Sytheon Ltd. While early research has shown promise for bakuchiol, most dermatologists today are sticking with retinoids because dozens of studies have demonstrated their effects. As Gohara said, women want choice, especially women with sensitive skin and pregnant women, and now that they have a choice, Something Bakuchiol is safe to use during pregnancy or breastfeeding.

Something Bakuchiol is not structurally similar to retinol, but it is emerging as an effective anti-photoaging option as a better-tolerated alternative to retinol. But the evidence pales in comparison to many standard skin care ingredients like fruit and ascorbic acid. The clinical research results provide necessary conditions for further expansion of the research population. In the future, it is necessary to focus on the optimal concentration, formulation application and mechanism of action of Something Bakuchiol.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

OUR MISSION
Help China Chemicals to benefit the happiness of human life
OUR VISSION
Become the most trusted chemical supplier in the world
OUR BUSINESS PHILOSOPHY
Striver – oriented, enrich employees, customer first, deep service, seek development
OUR VALUES
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.

Service

Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.

 

After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.

FAQ

Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.

 

HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?

You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.

Shipping

1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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