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Sodium Monofluorophosphate CAS 10163-15-2

Molecular Formula: FH3NaO3P

Formula Weight: 123.98

ZSpharmac: Sodium Monofluorophosphate Supplier

Product Name: Sodium Monofluorophosphate
CAS No: 10163-15-2
Purity: 99%

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Basic Info

Product Name:Sodium Monofluorophosphate
Other Names:Sodium Fluorophosphate
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White Powder
EINECS No.:233-433-0
Provide:Sodium Monofluorophosphate MSDS;
Sodium Monofluorophosphate COA

What is Sodium Monofluorophosphate?

Sodium monofluorophosphate (“MFP” for brief) is a white powdery strong with a melting point of concerning 626 ° C. It is quickly soluble in water as well as has solid hygroscopicity. Its solubility in water at 25 ° C is 42%. There is no rusting effect, the pH value of 2% aqueous remedy is 6.5-8.0, and also the liquid service undergoes slow hydrolysis when boiling, which can result in a reduction in mixed fluorine as well as a rise in free fluorine, so the purity is reduced. Acids can catalyze the hydrolysis of MFP; in alkaline or highly acidic solutions, or when there are cations that can form insoluble fluoride or low-solubility orthophosphate, the hydrolysis will be accelerated. Decahydrate can be obtained by crystallization from aqueous solution at 0°C. If the crystal water is removed by heating, it will lead to hydrolysis. Anhydrous sodium monofluorophosphate can be obtained by repeated extraction with ethanol or other organic solvents.

Sodium Monofluorophosphate Property

Melting point 625 °C
vapor pressure 0Pa at 20℃
solubility H2O: slightly soluble(lit.)
form Powder
color white
Water Solubility Soluble in water. Insoluble in ethanol and ether.


Application of Sodium Monofluorophosphate

Sodium Monofluorophosphate Preparation

There are many preparation methods of sodium monofluorophosphate, but they are mainly divided into three categories: ① melting method and molten salt process; ② liquid phase neutralization method; ③ gas phase fluorination method. Among them, the fusion method is a relatively traditional and widely used method, no matter from the research focus or the status quo of industrial application. The various processes will be described and compared in more detail below.

1. Melting method: The melting method mainly refers to the use of sodium metaphosphate (or positive, coke, sodium polyphosphate, etc.) and sodium fluoride as raw materials. , graphite, silver, platinum-rhodium alloy, etc. as the lining) and heated to 600-800 ° C in a molten state to react to obtain sodium monofluorophosphate, and the process flow is shown in the figure.

The fusion process was first developed and patented by CarlO.Anderson et al. in 1947 (Patent No. US2481807), and commercialized by Ozark-Mahoning Company in 1949. This process uses sodium metaphosphate and sodium fluoride as raw materials, heats and melts them in a closed platinum container at a temperature of 650-800°C, and obtains sodium monofluorophosphate finished product after cooling, with a purity close to 100%. The reaction formula is:

2. Liquid phase neutralization method: the United States Hans-WalterSwidersky et al. obtained a patent in 1995 (US5393506), and proposed a liquid phase neutralization method to prepare monofluorophosphate M2PO3F (M refers to the first main group metal cation in the periodic table, such as Na+) method. Its process is shown in the figure:

This method uses phosphoric acid, hydrofluoric acid, sodium carbonate or sodium hydroxide as raw materials for liquid-phase neutralization. With the evaporation, concentration, crystallization and drying of the neutralizing solution, the sodium monofluorophosphate product can be obtained. However, because fluorophosphoric acid is extremely corrosive, it has special requirements on equipment structure and materials, and the production process is difficult to control. The investment in production equipment is high, and the corrosion products are easy to introduce impurities into the product.

The Content of the Invention of Sodium Monofluorophosphate

The purpose of the present invention is to overcome the deficiency of existing production method, provide a kind of production method of sodium monofluorophosphate with low energy consumption, easy to get raw material, less impurities in the product introduced in the production process, and low product production cost.

The object of the present invention is achieved by the following technical solutions: with phosphoric acid and alkali (soda ash or caustic soda) as raw materials, the ratio of the two is sodium/phosphorus (Na/P) mol ratio=1: 1 ± 0.005, through neutralization, drying Polymerization, polymer polymeric sodium phosphate and sodium fluoride are mixed and melted to obtain monofluorophosphate sodium product, the ratio of polymeric sodium phosphate to sodium fluoride is: phosphorus/fluorine (P/F) molar ratio=1.000±0.005. There is no need to prepare monosodium metaphosphate, and sodium fluoride is used as the fluorinating agent for continuous production.

Its production method includes the following processes: 1. Polymerized phosphate preparation: feed alkali (soda ash or caustic soda) and phosphoric acid into a horizontal stirred wall scraping reactor, control the reaction temperature to be less than 95°C, and use the heat of reaction to evaporate a part of the water. After the neutralization is completed, the jacket of the reactor is heated up for dehydration and polymerization, and the temperature of the reactant rises to 250°C to 350°C and is kept for 45 to 60 minutes. The obtained polymerized sodium phosphate is in the form of acid pyrophosphate and a small part of metaphosphate Existence, moisture<0.2%.

2. Mixing of sodium fluoride: polymerized sodium phosphate and sodium fluoride are fed into the pulverizer at the same time for crushing and mixing, the molar ratio of polymerized sodium phosphate and sodium fluoride is controlled to be 1-10:10-1, and the pulverized material enters a mixer Homogenize.

3. Melting reaction: After homogenization, the mixture is continuously fed into the upper part of a carbonaceous reactor heated by power frequency, and the material is extruded from the bottom by the gravity of the upper material through the melting reaction. The residence time of the melting reaction is 14 to 18 minutes. The melt in the discharge pipe is solidified and blocked, and the discharge pipe is also equipped with a power frequency heating source. Control the temperature of the material at the outlet to 680°C to 730°C, feed the mixture continuously, and discharge the product continuously.

4. The melt is cooled and formed into flakes, crushed and sieved to obtain the product.

Compared with the prior art, the present invention has the following advantages: 1. The raw materials of phosphoric acid and alkali (soda ash or caustic soda) are easy to get and the cost is low.

2. Compared with sodium metaphosphate as raw material, the energy consumption is low, impurities are not easily introduced in the production process, and the product whiteness is high.

3. Compared with the neutralization method, there is no corrosion problem, and the investment in production equipment is small.

4. Compared with the fluorination method, there is no problem of gas treatment and environmental pollution, and it is a clean production process.

5. The production method of the present invention is easy for continuous production, and the production control is simple.

About Products:
If you need Sodium Monofluorophosphate as a cosmetic raw material, please contact our service staff directly, and we will provide you with high-quality products at the best price.
As an experienced manufacturer and supplier of Sodium Monofluorophosphate, ZSpharmac will provide Sodium Monofluorophosphate raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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