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Sodium Lauroylsarcosinate CAS 137-16-6

Molecular Formula: C15H28NO3.Na

Formula Weight: 293.38

ZSpharmac: Sodium Lauroylsarcosinate Supplier

Product Name: Sodium Lauroylsarcosinate
CAS No: 137-16-6
Purity: 99%

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Basic Info

Product Name:Sodium Lauroylsarcosinate
Other Names:Sodiumlauroylsarcosinate
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White Powder
EINECS No.:205-281-5
Storage:Room Temp
Provide:Sodium Lauroylsarcosinate MSDS;
Sodium Lauroylsarcosinate COA

What is Sodium Lauroylsarcosinate?

Salt Lauroylsarcosinate, the English name is SODIUMLAUROYLSARCOSINATE, aliases: salt lauroyl-N-methylglycinate, salt lauroyl-N-methylglycinate. The major features of salt lauroyl sarcosinate in cosmetics and skin care items are antistatic, foam booster, cleansing representative, as well as surfactant. The hazard variable is 3, which is relatively secure as well as also can be used with self-esteem.Generally, it has no result on expecting women. Sodium Lauroylsarcosinate has no comedogenic. FDA authorized sodium lauroyl sarcosinate can be used directly as an artificial additive, as well as CIR enables it to be utilized in rinse-off items and also leave-in items with a focus of no more than 5%.

Sodium Lauroylsarcosinate Property

Melting point 46 °C
density 1.033 g/mL at 20 °C
vapor pressure 0.02 hPa (20 °C)
RTECS MC0598960
Fp 267℃
storage temp. room temp
solubility H2O: 1 M at 20 °C, clear, colorless
form Powder
Specific Gravity1.03 (20/4℃)
color White
PH7.0-9.0 (25℃, 1M in H2O)
Water Solubility Soluble in water (293 g/L).


Sodium Lauroylsarcosinate Uses

  1. Salt Lauroylsarcosinate is an amino acid surfactant. Along with its excellent surface area activity, it additionally has the characteristics of anti-bacterial, anti-corrosion and anti-rust buildings as well as great biodegradability, so it is widely made use of in detergents, cosmetics, food and also beverage Rust, mineral flotation, pesticides and biomedicine as well as several various other fields.
  2. Salt Lauroylsarcosinate is a biochemical study. anionic surfactant. Hexokinase inhibitors. Anionic cleaning agent. Isolation of yeast ribonucleic acid. It can be made use of for RNA and DNA seclusion, as a lysing representative in cell purification, as an additive when dividing DNA from human lotion, and can likewise raise the nitrogen-fixing ability of leguminous rhizobia by adding this item. It additionally has many applications in immunochemistry.
  3. Salt Lauroylsarcosinate is an anionic surfactant.

Salt Lauroylsarcosinate Application

Fang Ningtao and others tried to use Salt Lauroylsarcosinate as a decellularization reagent to prepare decellularized tissue engineering scaffold materials, and analyzed their biological properties. Methods: The porcine valved pipeline was decellularized with 0.25% sodium lauryl sarcosine solution and nuclease, and its DNA and soluble protein content were determined, HE, Movat staining, electron microscope observation and biomechanical test ; Rat subcutaneous embedding test to analyze biocompatibility. Results After decellularization, the DNA content in the leaflets and wall of the valved duct was only 1.35% and 2.81% of the normal level, the soluble protein content was only 8.46% and 12.65% of the normal level, and the cellular components were almost completely removed. HE and Movat staining and electron microscope observation showed that the tissue structure was complete, the cell structure completely disappeared, and the main matrix components such as collagen, elastic fiber, and proteoglycan were fully preserved; the biomechanical properties of the valve were not significantly different from those of the normal valve; the biocompatibility of the scaffold Good, with low immunogenicity and degradability. Conclusion: Salt Lauroylsarcosinate is an ideal new decellularization reagent, by which a set of decellularization methods with low toxicity, high efficiency and no damage to tissue structure can be established, and decellularized scaffold materials with excellent biological properties can be prepared.

CN201710937850.8 discloses a descaling agent for drainage pipes. The present invention consists of the following raw materials in parts by weight: 8-16 parts of Salt Lauroylsarcosinate, 5-11 parts of sodium hydroxide, 7-15 parts of polyacrylamide, 4-10 parts of polymaleic anhydride, and 3-7 parts of hydroxyethylene acid , gallic acid 3-9 parts, hydroquinone 7-11 parts, hypochlorite 2-5 parts, citric acid 2-4 parts. The raw material cost of the invention is low, the preparation method is simple, the dirt formed in the drainage pipeline can be effectively removed, the dirt removal ability is strong, no secondary damage is caused to the pipeline, and the bacterial growth of the drainage pipeline is reduced.

CN201210162646.0 discloses a method for extracting Gram-positive bacterial nucleic acid. The invention provides a reagent for breaking the cell wall of Gram-positive bacteria, which consists of extract A and extract B; consists of extract A and extract B; the extract A is prepared according to the following method: Tris, EDTA , SDS, Tween-80, Triton-X-100, Brij-58, 3-[(3-cholesterylaminopropyl)dimethylamino]-1-propanesulfonic acid, Salt Lauroylsarcosinate, β-mercaptoethanol and water mixed , to obtain extract A; the extract B is prepared according to the following method: water-saturated phenol, ethanol and pyrrolidone are mixed to obtain extract B. Experiments of the present invention have proved that the present invention provides a method for efficiently extracting Gram-positive bacterial nucleic acids, which is simple to operate, very low in cost, and has good extraction effects, especially in extracting RNA, which is better than that currently widely used commercially available kits.

Synthesis of Salt Lauroylsarcosinate

1) Synthesis of lauroyl chloride: include a specific amount of lauric acid right into a completely dry three-necked flask furnished with a reflux condenser, warm and also thaw, and also control the temperature at 60-70e, gradually include phosphorus trichloride dropwise under complete mixing, as well as respond for 2 hrs, Stand for stratification, eliminate the phosphorous acid in the lower layer, as well as acquire the upper layer of lauroyl chloride.
2) Synthesis of Salt Lauroylsarcosinate: Include a specific amount of sodium sarcosinate solution as well as solvent tetrahydrofuran right into a four-neck flask with an electric stirrer as well as a reflux condenser, add lauroyl chloride and salt hydroxide liquid option dropwise while stirring, and also the response system The pH worth of the solution is regulated within the variety of 9 ~ 11. After the dropwise enhancement, the reaction is proceeded for 3 hrs. After the solvent is recovered, the pH worth is adapted to 1 ~ 2 with water down acid to transform N-lauroyl sarcosinate right into water-insoluble N-lauroyl Sarcosine, therefore separated from water-soluble not natural salt contaminations. Extract the product with ether, wash the upper oil layer with water till neutral, completely dry it with anhydrous salt sulfate, vaporize the solvent, and also recrystallize with oil ether to acquire white needle crystals.

Salt Lauroylsarcosinate Safety

Salt Lauroylsarcosinate can be discovered in the cosmetic database as a reasonably harmful component, mostly due to the fact that it might include pollutant nitrosamine (a popular carcinogen), and also since it is considered a penetration booster, which can change Skin framework that aids various other chemicals penetrate deep into the skin. CosmeticsInfo.org believes that salt lauroyl sarcosinate ought to not be utilized in cosmetics and also individual care products because of the capacity for the formation of N-nitroso compounds.
Salt Lauroylsarcosinate does not have actually the anticipated possible toxicity and damage, as well as it is dental with reduced toxicity. It was not located to be mutagenic, annoying or sensitizing. However, as pointed out earlier, it promotes the penetration of various other active ingredients right into the skin.

About Products:
If you need Salt Lauroylsarcosinate as a cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced Salt Lauroylsarcosinate manufacturer and supplier, ZSpharmac will provide Salt Lauroylsarcosinate raw materials for customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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