Zhishang Chemical

Welcome to Zhishang Chemical      +86-176 5311 3209     Simon@sdzschem.com

Zhishang Chemical

Sodium Cocoyl Glutamate CAS 68187-32-6

Molecular Formula: C5H9NO4?Na

Formula Weight: 0

ZSpharmac: Sodium Cocoyl Glutamate Supplier

Product Name: Sodium Cocoyl Glutamate
CAS No: 68187-32-6
Purity: 99%

Navigation Bar

Basic Info

Product Name:Sodium Cocoyl Glutamate
Other Names:Disodium2-aminopentanedioate
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Colorless to Pale Yellow Liquid
EINECS No.:269-087-2
Provide:Sodium Cocoyl Glutamate MSDS;
Sodium Cocoyl Glutamate COA

What is Sodium Cocoyl Glutamate?

In recent years, amino acid series surfactants have attracted much attention due to their safety, biodegradability and excellent surface activity. Sodium Cocoyl Glutamate is made of high-safety materials, which are extremely gentle to the skin, and will not cause allergies and phototoxicity; appropriate foam, strong washing power, and excellent adaptability to hard water; can be quickly decomposed by organisms; Contains fatty acid, so it can obtain the required viscosity in solution and micelle. Because of the above characteristics, it is widely used in transparent systems or (pearl) facial cleansers, shampoos, body washes, soaps, detergents, shaving creams, toothpastes and industrial products. It can also be used in silk dyeing and finishing, anti-rust additives, Metal processing, mineral flotation and oil extraction industries. It has extensive compatibility with other ingredients, which is lacking in other existing surfactants. The United States, Japan and Germany have put it into use in large quantities in the past 10 years, and marketed it in China at a price that is many times higher than the cost of raw materials.

There is little about the synthesis of Sodium Cocoyl Glutamate. Advances in Fine and Special Chemicals Technology 2003 (23) reported the synthesis method of N-lauroyl glutamic acid. The solvent is acetone, which is more toxic. Due to the characteristics of surface-active products of amino acid series , the residual acetone will cause the product to easily turn yellow, and the reaction time of this method is long, more than 18 hours, and the post-processing purification requires two recrystallizations, the technology is cumbersome and lengthy, difficult to operate, time-consuming and labor-intensive, and seriously violates the purpose of environmental protection and safety .

Properties of Sodium Cocoyl Glutamate

1. The amount of foam allows and likewise the irritability is tiny;
2. The thing has an all-natural coconut oil scent;
3. Substantially minimize the degreasing power of soap base;
4. Boost the foam form of the soap base as well as the rigidity after washing. Recommended dosage: major surfactant: 8%-30% (energetic internet content), auxiliary surfactant: 1%-6% (energised material), dental treatment things: 1%-3% (energetic product).


The Effect of Sodium Cocoyl Glutamate

Commonly, Sodium Cocoyl Glutamate has the basic homes of unfavorable surfactants such as emulsifying, washing, penetrating and also liquifying. Yet most significantly, the residential properties of salt cocoyl glutamate are low toxicity as well as mildness, as well as good human skin fondness. It can help our body to remove the dirt externally of the skin to the best level, and maintain the skin moist and also clear, therefore helping our body to execute the maintenance of the skin.

In addition to using salt cocoyl glutamate in the formulation of day-to-day chemicals, we can likewise use it in the formula of artificial additive, chemicals, and secondary oil extraction and also other commercial chemical product formulas to assist us boost the economy to the best level. advantages and also reduce industrial costs.

As a result, sodium cocoyl glutamate is not just a simple surfactant, it is also an important part of advertising the constant development of day-to-day usage products and also chemical items in our contemporary culture, however it needs to be noted that, After all, salt cocoyl glutamate is a chemical substance. Throughout the procedure of using it, we need to strictly follow its dose. The most effective proportion is 1-50%. After greater than 50%, sodium cocoyl glutamate is likely to shed its original surfactant benefit, which is not conducive to product processing and also production.

Sodium Cocoyl Glutamate Invention Contents

The purpose of the present invention is to provide a preparation method of cocoyl glutamic acid, which has the characteristics of simple operation, safety and high reaction yield in each step of the preparation route, and is easy to industrialize production.
The technical solution adopted to achieve the above purpose, including steps,

1) take coconut oil acid and phosgene as raw material, be 1: 1.05~3.5: 0.05~0.2 by the mol ratio of coconut oil acid, phosgene and catalyzer, under organic amine catalyst effect, coconut oil acid is at 70~120 ℃ Under the micro-melting state, the phosgene reaction was carried out for 5~30 hours, and the reaction was completed, and the cocoyl chloride was obtained by vacuum distillation under reduced pressure;

2) at room temperature, sodium glutamate is dissolved in the mixed solution of alcohol and water, and the mass ratio of alcohol and water is 1:1.0~10.0, after dissolving, the control system temperature is 0~50 ℃, under insulation and stirring, drip simultaneously. Add the aqueous solution of cocoyl chloride and sodium hydroxide, the mol ratio of sodium amino acid and cocoyl chloride is 1: 1.0~1.6, the time for adding is about 0.5~6 hour, and the rate of addition of sodium hydroxide and consumption are maintained at 6 with the system pH value Between ~ 15, dripping is completed, stirring 0.5 ~ 6h; Keep temperature at 0 ~ 100 DEG C, desolventizing under reduced pressure 0.5 ~ 6h; Cooling, temperature control at 0 ~ 50 DEG C, under stirring, slowly add hydrochloric acid dropwise , the amount of hydrochloric acid dripping is maintained between 0~10 with the pH value of the system, and the dripping is completed, and granular crystals are separated out, suction filtration, and after drying, the cocoyl glutamic acid is obtained.

beneficial effect
Compared with the prior art, the present invention has the following advantages;

(1) Cocoyl chloride is produced by the phosgene method, and a large amount of phosphorus-containing waste water will not be produced because phosphorus trichloride is used as a chlorination reagent. It is sold as hydrochloric acid, and carbon dioxide can be used to prepare sodium carbonate to achieve the effect of reuse and cost saving;

(2) the present invention adopts alcohol and water mixed solution to replace acetone and water mixed solution and pure water system in the traditional sense, avoids the generation of side reaction, solves the problem of product yellowing, improves product yield simultaneously, gained product Milder, better smell, color and quality;

(3) the present invention adopts the method of low-temperature desolvation and low-temperature crystallization to replace the method of traditional high-temperature acidification and liquid separation after the condensation stage is finished, which reduces the energy consumption in production, and greatly improves the operation while saving costs. security;

(4) The method for the cocoyl glutamic acid prepared by the present invention is easy to operate, has high reaction yield, is easy to industrialize production, and basically has no three wastes.

Embodiments of Cocoyl Glutamate

A preparation method of cocoyl glutamic acid, comprising the steps:

Step 1: in the 500ml there-necked flask equipped with stirring bar, thermometer, air conduit, reflux condenser, successively add coconut oil 284g (1mol), N,N-dimethylformamide 4.5g (0.06mol), heat up To 80 ℃, control reaction temperature is 80~85 ℃, pass into phosgene 105g (1.05mol), complete reaction in 5~8 hours, underpressure vacuum distillation, collect 140~180 ℃ (560Pa) cut, get Cocoyl chloride 265g, yield 90%.

Step 2: in the 100ml there-necked flask equipped with dropping funnel, thermometer and stirring, add sodium glutamate 191g (1mol), be dissolved in 446g ethanol and water mixed solution (m ethanol:m water=1:4), Stirring at normal temperature makes it dissolve, the cocoyl chloride is put into the dropping funnel of 500ml, the low temperature water bath temperature control is at 20~25 ℃, under stirring, add the cocoyl chloride 359g (1.2mol), drip 40% simultaneously Aqueous sodium hydroxide solution, the pH value of the reaction solution was maintained at pH=10~12, dripped, and continued stirring for 2h; after finishing, rising to room temperature, desolventizing under reduced pressure for 1h; cooling, temperature control at 15~20 ℃, stirring Hydrochloric acid was added dropwise to make the system pH=6~8, granular crystals were separated out, suction filtered, and after drying, 339 g of cocoyl glutamic acid was obtained, with a yield of 92%.

About Products:
If you need Cocoyl Glutamate, a cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced Cocoyl Glutamate manufacturer and supplier, ZSpharmac will provide Cocoyl Glutamate raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, and customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Sodium Cocoyl Glutamate Quotation