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Sodium Citrate Dihydrate CAS 6132-04-3

Molecular Formula: C6H9Na3O9

Formula Weight: 294.1

ZSpharmac: Sodium Citrate Dihydrate Cosmetic Raw Material Supplier

Product Name: Sodium Citrate Dihydrate
CAS No: 6132-04-3
Purity: 99%

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Basic Info

Product Name:Sodium Citrate Dihydrate
Other Names:Trisodium Citrate Dihydrate
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White Powder
EINECS No.:612-118-5
Storage:Store at +5°C to +30°C.
Provide:Sodium Citrate Dihydrate MSDS;
Sodium Citrate Dihydrate COA

What is Sodium Citrate Dihydrate?

Sodium Citrate Dihydrate, also known as citric acid trisodium salt dihydrate, has the chemical formula Na3C6H5O7·2H2O. It is a white crystalline powdery compound with an odorless, refreshing and salty taste. It is the hydrated form of the sodium salt of citrate produced by the reaction of citric acid with sodium hydroxide or sodium bicarbonate and contains two molecules of crystal water.

Sodium citrate dihydrate is relatively stable at room temperature. It begins to lose crystal water when heated to about 150°C, and is completely dehydrated at 300°C. It has high solubility in water, and the pH value of 5% aqueous solution is close to neutral, about 7.6 to 8.6. Therefore, it is often used as an acid-base buffer to adjust the acid-base balance of the solution.

Sodium Citrate Dihydrate Property

Melting point 

>300 °C(lit.)




173.9 °C

storage temp. 

Store at +5°C to +30°C.


H2O: 100 mg/mL






7.0-9.0 (25℃, 50mg/mL in H2O)



PH Range

7.5 – 9 at 29.4 g/l at 25 °C

Water Solubility 

720 g/L (25 ºC)

Sodium Citrate Dihydrate Uses

Food industry
Acidity regulator: Because it can dissociate citrate ions, it can effectively adjust the pH value in the food system, maintain the acid-base balance of the food, and maintain the taste and color stability of the food.
Preservatives: Used as food antioxidants and preservatives, they can delay the deterioration process of food and increase the shelf life.
Emulsifiers and Stabilizers: In dairy products and beverages, sodium citrate helps improve emulsion stability, increase foaming and consistency, and prevent fat separation.
Chelating agent: Forms a stable complex with metal ions to reduce the toxicity of heavy metal ions in food. It can also prevent oxidative browning caused by iron, copper and other elements in food.

Pharmaceutical industry
Anticoagulant: In medical laboratories, sodium citrate dihydrate is used to prepare anticoagulant solutions, such as ACD (citrate-phosphate-dextrose) solution, to prevent blood clotting during blood sample collection. , to ensure the accuracy of blood sample analysis.
Pharmaceutical preparation ingredients: As excipients, it may appear in tablets, injections, or other pharmaceutical preparations to provide buffering or help dissolve the drug.
Medical equipment disinfectant: Under certain conditions, sodium citrate can be used as a cleaning and disinfection aid for medical equipment.

Daily chemical industry
Oral care products: In toothpastes and other oral cleaning products, sodium citrate serves as a pH adjuster and stabilizing ingredient to help maintain a suitable oral environment.
Personal Care Products: In skin care and cosmetics, it acts as a mild pH balancer and moisturizer with a soothing effect on the skin.

Other apps
Water treatment: Sodium citrate can be used to soften hard water, reduce the concentration of calcium and magnesium ions in the water through chelation, and prevent scale formation.
Industrial Cleaners: Used as part of a cleaner formula to remove stains and deposits from metal surfaces while avoiding corrosion.
Experimental reagents: In chemical and biological laboratories, as a component of buffer solutions, they are used for cell culture, DNA extraction and other experiments that require control of pH reaction conditions.

Advantages of Sodium Citrate Dihydrate

  1. Excellent stability: Sodium citrate dihydrate is stable at room temperature and is not prone to hygroscopicity and deliquescence. It only shows slight deliquescence even in humid air and is not easily efflorescent in hot air, ensuring its storage and transportation convenience as a raw material. .
  2. Strong solubility: easily soluble in water and glycerin, and can be quickly dissolved in a variety of solvents to form a clear and transparent solution, which is easy to prepare and apply.
  3. pH adjustment performance: Sodium citrate is a good acid-base buffer and can effectively maintain the solution within a certain pH range, which is crucial for the manufacturing of products that require a stable acid-base environment, such as food, pharmaceuticals, cosmetics and personal care products. wait.
  4. Chelating properties: Sodium citrate can form stable chelates with metal ions to reduce the impact of metal ions on product quality, such as preventing rust smell in the food industry or reducing scale formation in water treatment.
  5. High safety: As a food additive, sodium citrate is non-toxic and safe for the human body. It is recognized by the World Health Organization and food safety agencies of various countries and is widely used in the food industry as a flavoring agent, buffer and stabilizer.
  6. Versatility: In addition to its wide application in the food industry, sodium citrate dihydrate is also suitable for use in the pharmaceutical field, such as as an anticoagulant, cosolvent or making disinfectant, as well as in daily chemical products as a stabilizer and pH adjustment agent.
  7. Environmentally friendly: Compared with some environmentally harmful chemicals, sodium citrate has good biodegradability and has relatively little impact on the environment.
  8. Cost-effectiveness: Citric acid, the raw material for the production of sodium citrate, has a wide range of sources and can be prepared through fermentation. The production cost is relatively controllable, so it has a high cost performance in many application fields.


National Center for Biotechnology Information. “PubChem Compound Summary for CID 71474, Trisodium Citrate Dihydrate” PubChem, https://pubchem.ncbi.nlm.nih.gov/compound/Trisodium-Citrate-Dihydrate. Accessed 17 April, 2024.

As a company specializing in the production and supply of Sodium Citrate Dihydrate raw materials, we are committed to providing customers with high-quality products and preferential prices. We have rich experience and technology to ensure product quality and stable supply. No matter where you are, we can provide you with the Sodium Citrate Dihydrate raw materials you need to support your production and research and development.

We always adhere to the principle of honest operation, strictly control product quality, and serve every customer with a customer-first attitude. Over the years, we have established good cooperative relationships with customers at home and abroad and won their trust and praise.

If you have needs or are interested in our products, please contact our service staff directly, we will wholeheartedly provide you with the best quality services and products. Looking forward to cooperating with you and developing together!

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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