Zhishang Chemical

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Sinomenine CAS 115-53-7

Molecular Formula: C19H23NO4

Formula Weight: 329.39

ZSpharmac: Sinomenine Raw Material Supplier

Product Name: Sinomenine
CAS No: 115-53-7
Purity: 99%

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Basic Info

Product Name:Sinomenine
Other Names:Sinomenine Hydrochloride
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White Smooth Crystal
EINECS No.:204-094-6
Storage:Store at +4°C
Provide:Sinomenine MSDS;
Sinomenine COA

What is Sinomenine?

Sinomenine is an alkaloid eliminated from the dried out stems of the deciduous twining creeping plants Sinomeniumacutum (Thunb.) Rehd.etWils and WilsvarcinereumRehd.etwils.Chemicalbook. Sinomenine has analgesic, antitussive, community anesthetic, antihypertensive, and anti-inflammatory homes, and can release histamine and hinder smooth muscle mass activity. It is scientifically taken advantage of to deal with countless extreme and chronic joint swelling, rheumatoid joint inflammation, rheumatoid joint swelling, and osteoarthritis. Joint inflammation, synovitis, icy shoulder, aged waistline and leg pain, soft cells injury, numerous neuropathic pain, and so forth.

Sinomenine Property

Melting point 180 °C (dec.)(lit.)
alpha D26 -71° (c = 2.1 in alc)
Boiling point 466.98°C (rough estimate)
density 1.2012 (rough estimate)
refractive index 1.5000 (estimate)
storage temp. Store at +4°C
solubility Soluble to 65 mg/mL (197.33 mM) in DMSO
form neat


Sinomenine Pharmacological Effects

Clinical Application of Sinomenine

In 1974, my nation started to use the rhizome of Ivy to deal with rheumatoid condition. In 1981, it was made into hydrochloride tablet computers. In 1983, Resources Hospital, Anshan Tanggangzi Physiotherapy Health Center, Shanghai Guanghua Health Center, and Xi’an Fifth Health center collectively made use of overall alkali of Ivy for therapy. 172 instances of rheumatoid condition were dealt with, and excellent outcomes were achieved, with a total efficient rate of 90.3%. In our group, the dosage was gradually increased from 120 mg/day to 300 mg/day within 2 weeks and maintained at this dose for an overall of three months. After therapy, the individual’s early morning tightness, grasp strength, joint tenderness, and joint swelling were significantly improved compared to the control group (p<0.05), and the efficient price was 83.3%. The most typical reaction during therapy is rash, which appears at different times. It usually occurs 1-2 weeks after taking the medicine, and it primarily happens in exposed components. The rash rate is about 46.7%. Second of all, granulocytopenia (2/30 situations) can be recouped after quiting the medication or lowering the dose. In addition to its analgesic and anti-inflammatory impacts in the therapy of rheumatoid disease, whether complete alkaloids of Sinomenaceae likewise has immune function-regulating effects still needs to be more checked out. Our team believe that the analgesic effect of total alkaloids shows up behind that of Tripterygium wilfordii, showing up regarding twenty days after taking the medication, and the effect is longer-lasting after quiting the medication.

Contact Us

About Products:
If you need Sinomenine as a cosmetic raw material, please contact our service staff directly and we will provide you with high-quality products at the best price.
As an experienced Sinomenine manufacturer and supplier, our company, ZSpharmac, will provide Sinomenine raw materials to customers around the world for a long time.
Over the years, the company has adhered to the spirit of “integrity management, strict quality control, and customer first” and has won unanimous praise from customers at home and abroad.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Sinomenine Quotation