Zhishang Chemical

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Zhishang Chemical

Silymarin Loges CAS 65666-07-1

Molecular Formula: C25H22O10

Formula Weight: 482.44

ZSpharmac: Silymarin Loges Supplement

Product Name: Silymarin Loges
CAS No: 65666-07-1
Purity: 99%

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Basic Info

Product Name:Silymarin Loges
Other Names:SilyMarin
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Light Orange to Brown Solid
EINECS No.:613-830-9
Provide:Silymarin Loges MSDS;
Silymarin Loges COA

What is Silymarin Loges?

Silybum marianum, alias: milk thistle, rat tendon, water pheasant, Latin name: Silybummarianum (L.) Gaertn., Compositae, Silybum marianum is an annual or biennial Asteraceae natural herb. Annual or biennial herb, 1.2 m high. Stems installed, branched, ribbed, rarely unbranched, all stems as well as branches with white silty cover, sparsely unshaven or dehaired. Seeds are utilized as medication. Belonging To Western Europe and North Africa. China is grown in Shaanxi, Gansu, Heilongjiang as well as Hebei areas. Plant height 30 ~ 200cm. Suches as cozy and likewise dry environment, prevents heat, suches as outstanding as well as totally dry environment, has strong flexibility, does not have stringent requirements on dirt and also water, and can be grown on sandy beach in addition to saline-alkali land. Milk thistle is an exceptional liver safety and security plant. Silymarin Loges is drawn out from milk thistle seeds.

Silybum marianum seed oil is a type of new health care food with plenty of high qualities, functions as well as likewise features, which is made from the fruit of Silybum marianum, a rare clinical in addition to edible plant with fascinating tales and tales. Silybum marianum seed oil is the highest grade of edible oils; Silybum marianum seed oil – the genuine “fluid gold”, “the very initial edible oil”. Silymarin Loges has actually been used for hundreds of years to manage liver ailment. Silymarin Loges markets the renewal of liver cells along with assists secure the liver from damaging variables.

Silymarin Loges Property

Melting point 158 °C
storage temp. -20°C
solubility Acetone (Slightly), DMSO (Slightly), Methanol (Very Slightly)
form Solid
color Light Orange to Brown


Silymarin Loges Uses

Silymarin Loges is an exceptional liver protection plant. Its seeds consist of new flavonoids, the primary component is SILYMARIN, a blend of Silymarin Loges, and is abundant in fat-soluble vitamins A, D, and E. It has great antioxidant function, can successfully feed on complimentary radicals, and also has a great cleansing feature for the liver by “damaging” the damage brought on by the multi-enzyme reaction to the body. It has a good health care impact on different liver as well as gallbladder symptoms such as liver cirrhosis, fatty liver, liver poisoning, cholecystitis, peri-cholecystitis, and also discomfort in cholelithiasis. main impact:
1. Prevent liver damage: form a protective film for liver cells, which can significantly decrease the damage to the liver caused by extreme alcohol.
( 1) Protection of liver cell membrane
Silymarin Loges has the result of anti-lipid oxidation, so as to maintain the flow of cell membrane layer as well as protect the liver cell membrane, as well as at the same time, it can likewise block mycotoxins such as a-arnanitine and also phalloidine. It binds to specific receptors on the liver cell membrane layer, inhibits its strike on the liver cell membrane layer as well as transmembrane transport, therefore disrupting its flow in the liver and intestinal tracts, and enhances the resistance of the liver cell membrane to different damages aspects. Wu Dongfang and also various other research studies found that silymarin can raise the fluidity of the superficial layer of liver microsomes as well as mitochondrial membrane layer, and also decrease the fluidity of the deep layer.

( 2) Advertise the repair work and also regeneration of hepatocytes
Silymarin Loges can trigger estradiol and boost the task of RNA polymerase in hepatocytes, thus enhancing the transcription of ribosomal RNA, advertising the synthesis of enzymes and architectural proteins, indirectly promoting the synthesis of DNA, and also finally promoting the fixing as well as regrowth of hepatocytes. This effect is common in broken hepatocytes as well as those remaining after partial hepatectomy.

( 3) Anti-hepatic fibrosis
Liver fibrosis describes the too much deposition of thirsty extracellular matrix (specifically collagen) in the liver. At present, the treatment of main illness triggers, such as removal of hepatotoxic compounds, is still the primary treatment instructions for human anti-hepatic fibrosis. With the further understanding of the pathogenesis, brand-new restorative techniques focusing on inhibiting hepatic stellate cell activation, hindering matrix synthesis and advertising matrix decomposition are gradually being accepted by medical professionals as well as patients. Researches have actually revealed that the main web link of liver fibrosis is the activation of hepatic stellate cells (HSCs), which are the primary cells that generate extracellular matrix., cytokines and also development elements and various other intricate effects. Restraint of hepatic stellate cell activation as well as its involved impacts is particularly essential for hepatic fibrosis of unknown etiology and no details therapy for the source of persistent liver injury. Researches have confirmed that Silymarin Loges achieves anti-hepatic fibrosis by anti-oxidation and straight preventing the activation of numerous cytokine-activated HSCs.
2. Auxiliary liver disease: enhances and also fixings the liver. By boosting protein synthesis, it can advertise liver cell repair service as well as advertise cell regrowth. The symptoms and also liver feature of clients with hepatitis were dramatically boosted.
3. It can reduce the opportunity of liver cells being harmed by free radicals and also safeguard the liver cell membrane. Has anti-radiation impact.
4. Control the secretion of bile, aid digest fat, as well as additionally nourish the stomach, spleen, gallbladder as well as kidney.
5. Offer nutrients to the blood circulation system as well as minimize cardio issues, consisting of atherosclerosis and also hypercholesterolemia.

Preparation of Silymarin Logs

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Silymarin Loges Quotation