Sesamol Powder CAS 533-31-3

Molecular Formula: C7H6O3

Formula Weight: 138.12

ZSpharmac: Sesamol Powder Supplier

Product Name: Sesamol Powder

CAS No: 533-31-3

Purity: 99%

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Basic Info

Product Name:	Sesamol Powder
Other Names:	Sesamol
CAS:	533-31-3
Place of Origin:	Shandong, China
Brand Name:	ZSpharmac
Type:	Cosmetic Raw Materials
Appearance:	Off-White to Tan Crystalline
EINECS No.:	208-561-5
Storage:	Room Temperature
Provide:	Sesamol Powder MSDS； Sesamol Powder COA

What is Sesamol Powder?

Sesamol, additionally known as 3,4-methylenedioxyphenol, is a fat-soluble lignan compound. It is a vital component of sesame oil and a crucial quality stabilizer of sesame oil. Sesamol Powder exists in sesame seeds, sesame oil and also sesame meal, and also can be produced by continuous decomposition of sesamolin throughout thermal handling, with an optimum of 64.4 mg/(100g) in sesame oil.

Sesamol Powder has really strong antioxidant capacity as well as has been verified to have anti-inflammatory and digestive tract feature policy effects. It is often utilized as an antioxidant in food and also medicine, as well as it is additionally an important starting material for the synthesis of antihypertensive drugs and also cardio drugs, and it is likewise a basic material for the pesticide piperonyl butyl ether. Sesamol Powder remains in wonderful need worldwide, particularly in the field of medication synthesis.

Sesamol Powder Property

Melting point	62-65 °C (lit.)
Boiling point	113-116°C 2mm
density	1.2112 (rough estimate)
refractive index	1.4850 (estimate)
Fp	113-116°C/2mm
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Chloroform, Methanol
pka	10.08±0.20(Predicted)
form	crystalline
color	off-white to tan
Water Solubility	slightly soluble

Sesamol Powder Uses

Sesamol Powder is an essential scent element of sesame oil as well as a vital quality stabilizer of sesame oil; it is extensively used in the preparation of anti-mold and antibacterial agents, anti-cancer, anti-hypertensive medications, and also hair conditioners for premium shampoos; it is a pricey chemical, Pharmaceutical intermediate basic material, with good advancement and utilization value and also application possibility; it is an essential intermediate in the synthesis of anticancer medications and pesticide synergists, as well as also utilized as an intermediate for antihypertensive and cerebrovascular condition medications.
Sesamol Powder can react with acid, aldehyde, alcohol (phenol) and various other substances to create ester and ether derivatives. It is extensively made use of in the preparation of a collection of great chemicals such as anti-mold and also anti-bacterial representatives, anti-cancer and anti-hypertensive medicines, as well as hair conditioners for premium shampoos. It is an expensive chemical and also pharmaceutical intermediate resources with great advancement and also use worth as well as Application possibility. It is additionally an important intermediate in the synthesis of anticancer drugs and also pesticide synergists, along with an intermediate in antihypertensive as well as cerebrovascular illness drugs.
Sesamol Powder is used as antioxidant, pharmaceutical intermediate and also cosmetic additive.

Synthesis of Sesamol Powder

There are three major synthetic techniques for Sesamol Powder: one is extraction from sesame oil, the various other is full synthesis from piperonylamine, as well as the third is semi-synthesis from jasmonal. To extract Sesamol Powder from sesame oil, the solvent usage is huge, the price is high, as well as it is not ideal for commercial manufacturing; the complete synthesis route beginning with piperonylamine needs to be diazotized and also hydrolyzed, and the return of sesamol is reduced. Combining and also side responses certainly happen in the chemicalization and hydrolysis procedure to form pigment materials that are hard to eliminate, so the color of Sesamol Powder is not good, as well as the application is limited; the semi-synthetic path beginning with jasminal is the most industrially applicable process Line, item top quality and shade are all great. The synthesis of sesamol from jasmonal mainly undergoes two actions of oxidation and hydrolysis. In this project innovation, inexpensive oxidant as well as reactive extraction innovation are made use of, to ensure that the created item is rapidly divided from the response zone, which significantly lowers the event of side responses. The return can get to more than 60%, as well as the product web content is 98%, which is beige crystal.

A Review of the Current Pharmacological Opinion on Sesamol Powder: a Review

The medicinal worth of sesame (Sesamum indicum L.) seeds has been confirmed in Chinese as well as Indian systems of medication. Its countless possible nutritional benefits are attributed to its primary bioactive part, sesamol. As a result of these researches, several molecular systems have actually arised defining the pleiotropic organic results of sesamol. This review sums up the most interesting in vitro and also in vivo research studies on the organic impacts of sesamol. The present job summarizes the information readily available in the Pubmed and Scopus data sources. A number of molecular systems explaining the pleiotropic biological effects of Sesamol Powder have been illuminated. Its primary restorative impacts have actually been shown in the control of oxidative and also inflammatory conditions, metabolic disorder and state of mind conditions. Better, compelling evidence mirrors Sesamol Powder’s ability to inhibit inflammatory cell expansion, stop intrusion as well as angiogenesis by influencing numerous molecular targets and downstream mechanisms. Sesamol is a risk-free, harmless chemical that mediates anti-inflammatory results by downregulating the transcription of inflammatory pens such as cytokines, redox status, healthy protein kinases, as well as enzymes that advertise inflammation. Furthermore, Sesamol Powder likewise induces apoptosis in cancer cells via activation of mitochondrial and also receptor-mediated paths and also caspase cascades. This evaluation summarizes several medicinal impacts of Sesamol Powder, particularly, antioxidative, anticancer, neuroprotective, cardioprotective, anti-inflammatory, hypolipidemic, radioprotective, antiaging, antiulcer, antidementia, antidepressant, antiplatelet, anti Convulsion, anxiolytic, injury healing, cosmetic (skin whitening), antimicrobial, matrix metalloproteinase (MMPs) inhibition, hepatoprotective activity and various other organic effects. Right here, we summarize the proposed devices behind these pharmacological impacts.

Sesamol Powder Ecological Information

The manufacturing as well as use of Sesamol Powder as a chemical intermediate will lead to its launch to the environment via various waste streams. Sesamol is a component in sesame and also seed oils. If launched to air, the estimated vapor stress at 25 ° C is 6.9X10-3 mmHg, which indicates that Sesamol Powder will just exist in the environment as a vapor. Vapor-phase sesamol reacts with photochemically generated hydroxyl groups to break down totally free radicals in the ambience; the half-life of this reaction in air is estimated to be 2 hours. Sesamol has a chromophore that absorbs at > 290 nm and also hence might be prone to photolysis by straight sunshine. If released into soil, Sesamol Powder is expected to be very mobile based upon an approximated Koc of 48. Sesamol has a pKa of 9.97, suggesting that the compound exists as a weak anion, which anions usually do not adsorb more highly right into natural carbon-containing soils and also clays than their neutral equivalents. Volatilization from moist soil surfaces is expected to be a significant fate process based on an estimated Henry’s law constant of 6.9X10-6 atm-cu m/mole. Based on its vapor stress, Sesamol Powder is not expected to vaporize from completely dry dirt surface areas. Biodegradation data in dirt or water are not readily available. If launched into water, sesamol is not anticipated to adsorb to suspended solids as well as debris based upon the approximated Koc. Volatilization from water to the surface is anticipated to be an essential fate process based upon the approximated Henry’s legislation constant for this substance. The estimated volatilization half-lives were 5 days and 41 days for the model river and also version lake, specifically. An estimated BCF of 5 shows a low capacity for bioconcentration in water microorganisms. Hydrolysis is not expected to be a crucial ecological destiny procedure since the substance lacks practical teams that hydrolyze under ambient problems (pH 5 to 9). Work-related exposure to Sesamol Powder may arise from breathing and also facial direct exposure to this substance in work environments where sesamol is created or used. Restricted monitoring information recommend that the general population might be exposed to Sesamol Powder via consumption of foods containing sesamol.

Company Profile and Corporate Culture

Company Profile：

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture：

OUR MISSION
Help China Chemicals to benefit the happiness of human life
OUR VISSION
Become the most trusted chemical supplier in the world
OUR BUSINESS PHILOSOPHY
Striver – oriented, enrich employees, customer first, deep service, seek development
OUR VALUES
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info

Business Type: Manufacturer
Product Range: Cosmetic raw materials
Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
Total Employees: 51~100
Capital (Million US $): 10000000RMB
Year Established: 2016

Production Capacity

No. of Production Lines : 8
No. of QC Staff : 5 -10 People
OEM Services Provided : yes
Factory Size (Sq.meters) : 3,000-5,000 square meters
Certificate: ISO9001 , CE , GMP , API , MSDS
Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.

Service

Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.

After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.

FAQ

Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.

HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?

You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

Is there a discount?

Different quantity has different discount.

Shipping

1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.