Zhishang Chemical

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Zhishang Chemical

Sclareolide CAS 564-20-5

Molecular Formula: C16H26O2

Formula Weight: 250.38

ZSpharmac: Sclareolide Supplement

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Product Name: Sclareolide
CAS No: 564-20-5
Purity: 99%

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Basic Info

Product Name:Sclareolide
Other Names:Ginkgo Fruit Powder
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White to Off-White Neat
EINECS No.:209-269-0
Storage:Sealed in Dry,Room Temperature
Provide:Sclareolide MSDS;
Sclareolide COA

What is Sclareolide?

Clareolide (Norambreinolide) is a sesquiterpene lactone natural product derived from a choice of plant sources, including Salvia yosgadensis, Salvia sclarea, as well as stogie cigarette. Sclareolide is a close analog of sclareol, an antifungal diterpenoid produced on the dropped leave surface area of Nicotiana. In addition, Sclareolide is used as an aroma in cosmetics along with has actually lately been marketed as a weight decrease supplement.
Artificial insemination: Sclareolide (20, 100 and also 500 μM) dose-dependently causes NpABC1 expression of plasma membrane layer healthy protein in cigarette leaf tobacco cells. In spite of induction of NpABC1 expression, Sclareolide (20 μM) had no impact on cigarette leaf tobacco cell growth. Furthermore, NpABC1 records levels were high and after that decreased 3 hrs after Sclareolide enhancement. Nonetheless, NpABC1 protein expression degrees remained fairly stable for up to 12 h. The 160-kD NpABC1 healthy protein is located in the plasma membrane and also is involved in the secretion of secondary metabolites that play a crucial function in plant defense.

Sclareolide Properties:

Melting point 

124-126 °C (lit.)


47 º(c=2, chloroform)

Boiling point 

321.4±10.0 °C(Predicted)


1.009±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature


Chloroform (Slightly), DMSO (Slightly)




White to Off-White

Sclareolide Uses

  1. Sclareolide is an excellent tobacco flavor agent. In the mixed cigarette, it can hide the rough and also miscellaneous gas of the cigarette to boost and enhance the scent quality, offer the tobacco a pleasant particular fragrance, make the cigarette softer and smooth in the mouth, and it is a reliable flavoring as well as corrective representative. Sclareolide has been commonly utilized in the food market for its capacity to enhance and also enhance the sensory residential or commercial properties of foods. It can be utilized in foods containing pleasant condiments as a flavor representative to boost the olfactory result of food. Adding a small amount of sclareolide in the coffee sector can raise the resentment of coffee as well as boost the rejuvenating impact of coffee without cardio stimulation. In many cases, when lowering body fat, Sclareolide has been widely utilized in weight reduction items because it can aid enhance the mass of the lean body.
  2. Sclareolide is used to create numerous premium cosmetics and also numerous premium fragrances.

Oxidative Metabolism of Ambroxan and Sclareolide by Botrytis Cinerea

Ambrox is a spice diterpene that is xenobiotically metabolized by the phytopathogenic fungus Botrytis cinerea to provide the primary product, 1beta-hydroxy-8-epiambrox (60%), and three minor metabolites, 3β-hydroxyandrolone Sialyl ether, sclareolide and 3β-hydroxysclareolide. Sclareolide is a cytotoxic diterpene lactone that is fermented with the same fungi to produce 3β-hydroxysclareolide (59%) as the major metabolite and two minor metabolites, namely 1 – Ketosclareolide and 3beta,14-dihydroxycilanolide.

Discovery of Sclareol and Sclareolide As Filovirus Entry Inhibitors

Filoviruses trigger serious hemorrhagic fever in human beings. Ebola virus (EBOV) is the most contagious filovirus. Regardless of the use of thoughtful treatment during one of the most current Ebola episode, new anti-EBOV drugs are urgently needed. In this research study, 2 natural items of sclareolide, sclareol and sclareolide, were recognized as EBOV entrance inhibitors by blocking the viral fusion procedure with EC 50 s of 2.4 μmol/ L as well as 8.0 μmol/ L, respectively. L. In addition, both substances displayed inhibitory impacts on all filoviruses tested, indicating their broad-spectrum task against filoviruses. This research study supplies insights right into these 2 all-natural products and their application to filovirus transmittable illness.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Sclareolide Quotation