Rhodiola CAS 86831-54-1

Molecular Formula: 86831-54-1

Formula Weight: 610.52

ZSpharmac: Rhodiola Supplier

Product Name: Rhodiola

CAS No: 86831-54-1

Purity: 99%

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Basic Info

Product Name:	Rhodiola
Other Names:	RHODIOSIN
CAS:	86831-54-1
Place of Origin:	Shandong, China
Brand Name:	ZSpharmac
Type:	Cosmetic Raw Materials
Appearance:	Dark Yellow to Very Dark Yellow Solid
EINECS No.:	N/A
Storage:	2-8°C
Provide:	Rhodiola MSDS； Rhodiola COA

What is Rhodiola?

Rhodiola grows on a plateau above 4,000 meters above sea level. It can show tenacious and lush vitality under harsh natural conditions such as strong ultraviolet radiation from the sun, huge temperature difference between day and night, and very dry climate, which shows that it has a special storage capacity in its body. living matter. In the process of research on Rhodiola rosea in the Tibetan plateau, it was found that when the rhodiola root with dry skin was cut open, rich colloidal liquid immediately exuded from the inside, indicating that it has a strong moisturizing function. On the skin, it has rapid anti-inflammatory, wound healing and obvious moisturizing and emollient effects.

During the research and production, the skin of hands often soaked in Rhodiola rosea extract is obviously white, smooth and delicate. Practice has proved that rhodiola rosea has good skin care effects and can be used as a natural cosmetic component without pollution in the snowy area. Years of scientific research have confirmed that: Rhodiola contains unique salidroside and aglycone tyrosol, which can activate skin cell metabolism and keep it youthful; natural SOD scavenge free radicals, anti-aging skin; rich polyphenols, It can absorb various bands of ultraviolet rays respectively, and has good anti-radiation and anti-photoaging functions; polysaccharide ingredients have good moisturizing functions; Rhodiola contains 18 kinds of amino acids, 35 kinds of trace elements and vitamins A, C, D, E, which can Provides natural nourishment to human cells. The known water extraction method and alcohol extraction method not only have low active ingredient content in the rhodiola obtained, but also contain many complex ingredients that are not absorbed by human skin and are not beneficial to skin care, such as soluble starch, sugar species, cellulose, etc. Using the supercritical extraction method, the above-mentioned beneficial ingredients to skin cells in Rhodiola can be fully and selectively extracted and separated, and the content of effective skin care active ingredients is more than double that of the water extraction method. The content of tenososide is 1-2.5%, SOD is 0.3%, polyphenol is 3%, polysaccharide is 4.5%. In supercritical extraction of rhodiola, salidroside is 5-6%, SOD is 2%, polyphenol is 6%, polysaccharide is 10%, and supercritical extraction of rhodiola is easier for skin to penetrate and absorb , its moisturizing, astringent, antibacterial, anti-ultraviolet light, whitening, freckle-removing, anti-aging and other effects are twice as high as that of water-extracted rhodiola.

Rhodiola Property

Melting point	195-199 °C
Boiling point	994.3±65.0 °C(Predicted)
density	1.82±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Acetone (Slightly, Heated, Sonicated), Methanol (Slightly)
form	Solid
pka	6.67±0.40(Predicted)
color	Dark Yellow to Very Dark Yellow

Rhodiola Uses

Rhodiola has good skin care effect and can be used as a non-polluting natural cosmetic component. Years of scientific research have confirmed that Rhodiola contains unique salidroside and glucoside tyrosol, which can activate skin cell metabolism and keep it youthful; natural SOD scavenge free radicals and resist skin aging; rich in polyphenols The ingredients can absorb various bands of ultraviolet rays respectively, and have good anti-radiation and anti-photoaging functions; polysaccharide ingredients have good moisturizing functions; Rhodiola contains 18 kinds of amino acids, 35 kinds of trace elements and vitamins A, C, and D , E, can provide natural nourishment to human cells. The known water extraction method and alcohol extraction method not only have low active ingredient content in the obtained Rhodiola, but also contain many complex ingredients that are not absorbed by human skin and are not beneficial to skin care, such as soluble starch, sugar, fiber Su and so on. The supercritical extraction method can fully and selectively extract and separate the above-mentioned beneficial ingredients in Rhodiola rosea, and its effective skin care active ingredient content is more than double that of water extraction method, such as water extraction of Rhodiola rosea Salidroside content is 1-2.5%, SOD is 0.3%, polyphenol is 3%, polysaccharide is 4.5%. In supercritical extraction of Rhodiola, salidroside is 5-6%, SOD is 2%, polyphenols is 6%, polysaccharide is 10%, and supercritical extraction of rhodiola is easier to be penetrated and absorbed by the skin. , astringent, antibacterial, anti-ultraviolet light, whitening, freckle, anti-aging and other effects are twice as high as water extraction method rhodiola.

Application of Rhodiola

1) Anti-aging: The effect of rhodiola rosea extract—rhodiola, a medicinal plant, on the culture of human embryonic lung diploid fibroblasts (2BS) and rat liver in vitro was investigated by combining in vitro and in vivo research methods , Observed the effect of Rhodiola on the growth and proliferation of 2BS cells, as well as the changes in the morphology and histochemistry of rat liver cells and the changes of lipid peroxide (LPO) and liver serum superoxide dismutase (SOD) in liver tissue. The result of the experiment is that rhodiola can promote the growth and proliferation of 2BS cells, reduce the content of LPO in rat liver tissue and lipofuscin in liver cells, and the activity of acid phosphatase (ACPase). The results prove that Rhodiola has the effect of delaying cell aging and anti-degeneration.

2) Anti-senile dementia: In an experiment, D-galactose was injected intraperitoneally for 6 consecutive weeks, and Aβ140 was injected bilaterally into the hippocampus to create an AD rat model. The learning and memory behavior of rats was detected by Y-maze and one-time passive avoidance test, the content of lipofuscin in cerebral cortex, the fluidity of mitochondrial membrane, SOD activity and MDA content in hippocampus were measured, and the ultrastructure of hippocampus was observed by electron microscope. Results Rhodiola can significantly improve the learning and memory impairment of dementia rats, significantly reduce the hippocampal SOD activity, MDA content and cortical lipofuscin content of dementia rats, and inhibit the degeneration and apoptosis of hippocampal neurons. Therefore, rhodiola may have a certain preventive effect on senile dementia rats by affecting the level of free radicals

3) Effect of Rhodiola on biochemical indicators such as blood sugar in diabetic rats. Of 25 SD rats, 5 were randomly selected as the blank control group, and the remaining 20 were treated with alloxan-induced diabetes. After successful modeling, they were randomly divided into an experimental group (10 rats) and a control group (10 rats). The experimental group used the extract of Rhodiola angustifolia——Rhodiola rosea, and injected it into the rats of the experimental group through the tail vein every 3 days. On the 32nd day, the blood was taken by cutting off the head, and the blood sugar, transaminase, urea nitrogen and blood routine indicators of each rat were measured. . Results Rhodiola had no significant (P>0.05) effect on blood glucose, BUN, MCV, MCH, MCHC, PLT in diabetic rats; but compared with the control group, GPT, RBC, HCT, HGB, RDW, WBC were significantly A significant (P<0.05) increase occurred. Therefore Rhodiola can alter the normal physiological function of the liver.

4) Anti-tumor: The effect of rhodiola on liver cancer was explored by combining the research method of in vitro cultured liver cancer cells (7721) and transplanted liver cancer (H22) in mice. The experimental results show that rhodiola can inhibit the growth and proliferation of 7721 and H22 liver cancer cells, reduce DNA synthesis, increase glycogen content, improve the quality of life of tumor-bearing mice and prolong their survival period. According to the results of flow cytometry, rhodiola can inhibit the S phase (DNA synthesis phase) of liver cancer cells cultured in vitro. It is suggested that rhodiola has a certain inhibitory effect on 7721 and H22 liver cancer cells.

Preparation of Rhodiola

Rhodiola is prepared by CO2 liquid phase supercritical extraction process. The technical scheme is that the rhizome of Rhodiola rosea is washed, dried in the sun, and crushed into granules for subsequent use. Heat or cool the extraction kettle, separation kettle I, and separation kettle II respectively (the set temperature is: extraction kettle 30°C, separation kettle I 65°C, separation kettle II 40°C), and open the CO2 cylinder (the flow rate is 10- 20Kg.h-1), and pressurize the system at the same time, when the set pressure is reached (the set pressure is: extraction kettle 20Mpa, separation kettle Ⅰ 12Mpa, separation kettle Ⅱ 6Mpa), close the gas cylinder, and after constant temperature and pressure cycle extraction for 150 minutes , decompress and recover the gas, and take out the rhodiola powder from the separation kettle. Rhodiola powder can be directly added with water to make a pure Chinese medicine mask, or it can be added with deionized water and emulsified by vacuum homogenization to make pure natural rhodiola skin cream and skin care lotion, and can also be used as a natural component of other cosmetics with different functions . If the finished product is required to be pure white or transparent, Rhodiola must be decolorized.

About Products:
If you need Rhodiola as a cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
Our company as an experienced Rhodiola producer and supplier,
ZSpharmac will provide Rhodiola raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile：

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture：

OUR MISSION
Help China Chemicals to benefit the happiness of human life
OUR VISSION
Become the most trusted chemical supplier in the world
OUR BUSINESS PHILOSOPHY
Striver – oriented, enrich employees, customer first, deep service, seek development
OUR VALUES
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info

Business Type: Manufacturer
Product Range: Cosmetic raw materials
Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
Total Employees: 51~100
Capital (Million US $): 10000000RMB
Year Established: 2016

Production Capacity

No. of Production Lines : 8
No. of QC Staff : 5 -10 People
OEM Services Provided : yes
Factory Size (Sq.meters) : 3,000-5,000 square meters
Certificate: ISO9001 , CE , GMP , API , MSDS
Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.

Service

Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.

After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.

FAQ

Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.

HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?

You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

Is there a discount?

Different quantity has different discount.

Shipping

1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.