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Resveracel CAS 501-36-0

Molecular Formula: C14H12O3

Formula Weight: 228.24

ZSpharmac: Resveracel Supplier

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Product Name: Resveracel
CAS No: 501-36-0
Purity: 99%

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Basic Info

Product Name:Resveracel
Other Names:Resveratrol
CAS:501-36-0
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Off-White Powder
EINECS No.:610-504-8
Storage:-20°C
Provide:Resveracel MSDS;
Resveracel COA

What is Resveracel?

Resveracel is an anthraquinone terpene material, normally came from the origin significance of Polygonumcuspidatum Sieb.etZucc. Polygonum cuspidatum: seasonal shrub-like natural herb, approximately more than 1 meter high. Rhizome recumbent underground, woody yellow-brown, with recognizable knots. The stem is erect, cylindrical, glabrous externally, scattered with many red locations, hollow. Singular leaves rotating, extensively ovate to almost round, 7-12cm long, 5-9cm broad, peak soon intended, base round or cuneate; petiole 1-1.5 centimeters long, filmy, brown, caducous. The flowering period is from July to September, as well as the fruiting period is from September to October. It can be excavated in spring as well as additionally fall, cut off in addition to dried in the sunshine. Frequently birthed in valleys, streams or financial institutions. Dispersed to the primary in addition to southern parts of the nation, created in Jiangsu, Zhejiang, Jiangxi, Fujian, Shandong, Henan, Shaanxi, Sichuan and numerous other areas.

Resveracel is a natural anti-oxidant that can reduce blood viscosity, avoid platelet gathering in addition to vasodilation, maintain blood streaming, prevent the occasion and also growth of cancer cells, and have anti-atherosclerosis, coronary cardiovascular disease, heart disease, Evasion and treatment of hyperlipidemia. The swelling suppressing impact also has an estrogen-like result, which can be utilized to deal with diseases such as breast cancer cells.It can delay aging and also stop cancer. It is truly high in red grape skin, red wine as well as also grape juice. Research studies have really divulged that the security of chromosomes will definitely be damaged as people age, and resveratrol can turn on a healthy and balanced protein sirtuin that fixings chromosome health and wellness as well as wellness, as a result delaying aging.

Resveracel Property

Melting point 253-255°C
Boiling point 449.1±14.0 °C(Predicted)
density 1.359±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).
form Powder
pka9.22±0.10(Predicted)
color Off-white
Water Solubility Soluble in water (3 mg/100mL), ethanol (50 mg/mL), DMSO (16 mg/mL), DMF (~65 mg/mL), PBS (pH 7.2) (~100µg/mL), methanol, and acetone (50 mg/mL).

 

Efficacy of Resveracel

(1) Antipyretic and analgesic effects
Resveracel can apply its antipyretic and also analgesic restorative effect via several ways. Speculative researches by pharmacists on rats have actually shown that resveratrol can enhance the gastric mucosa with the capability to stand up to anxiety abscess brought on by subdued gastric secretion without affecting blood pressure.

( 2) Anticancer effect
Resveracel impacts discrete stages of carcinogenesis by regulating signal transduction pathways managing cellular division as well as growth, apoptosis, inflammation, angiogenesis, as well as metastasis.
Resveratrol as well as by-products for the prevention and treatment of cancer cells released in the journal Medication Discovery Today in 2010 systematically evaluated the anticancer activity of resveratrol as well as its by-products, explaining that resveratrol and also its by-products have high anticancer task.

( 3) Antioxidant impact
Resveracel is a natural antioxidant that exists in a range of plants. It generally plays an antioxidant role by scavenging or preventing the generation of oxidative complimentary radicals to hinder lipid peroxidation as well as regulate the tasks of relevant enzymes related to antioxidant features. When the blood web content of resveratrol is 1.3 μg/ mL and also above, it can significantly inhibit the lipid peroxidative hemolysis of red blood cells in rats, as well as have evident effects on the lipid peroxidation of rat skin, heart, kidney and various other body organs. restraint.
The medicinal feature of resveratrol to inhibit or get rid of oxidative totally free radicals has attracted comprehensive attention of scientists, as well as it involves many physiological diseases very closely pertaining to human health and wellness, such as atherosclerosis, drug-induced and viral liver disease, intense or persistent Stomach ulcers, allergies, etc( 4) Anti-inflammatory and anti-bacterial effects
The combination of microorganisms as well as inflammatory responses is the source of numerous skin diseases, eg Staphylococcus aureus infection of hair roots, folliculitis. Redness and itching prevail indications of athlete’s foot, jock itch, as well as corporis. A mix of antimicrobial and also anti-inflammatory therapies is an excellent therapy method for the relief of this skin disease. For that reason, scientists additionally explored whether resveratrol has antimicrobial activity versus microorganisms and also fungi.

The results of antibacterial experiments reveal that Resveracel has a solid inhibitory effect on Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa as well as various other fungis. On the other hand, anti-inflammatory experimental studies have revealed that resveratrol accomplishes therapeutic results by minimizing the bond of platelets and changing the task of platelets during the anti-inflammatory procedure.

Pharmacology of Resveracel

Resveracel is not only a chemopreventive agent for lump diseases, but likewise a chemopreventive representative for reducing platelet aggregation, avoiding and also treating atherosclerosis, and also cardio and cerebrovascular illness. In the 1990s, Chinese clinical and also technical workers continued to grow their research study on resveratrol, and also disclosed its pharmacological effects: inhibiting irregular gathering of platelets, protecting against coronary infarction and analytical embolism, securing the hypoxic heart, as well as dealing with burns or blood loss. It can efficiently recover the reduced heart result caused by shock, expand arteries and also improve microcirculation.
In 1998, Al Mindel of the United States kept in mind Resveracel as one of the “100 most noticeable and efficient anti-aging substances” when putting together the “Anti-aging Holy Publication”. Yu Shanlin, a researcher at the Peanut Research Institute of the Chinese Academy of Agricultural Sciences and Educator Mao Wenyue, a prominent nationwide medical expert, said that the content of resveratrol in peanuts (the product of protein as well as fat in peanuts is more than that of meat as well as eggs, and additionally the ancients called it “sturdiness fruit”) Research and development will be amongst among one of the most critical nutrition topics in the 21st century. Previously, NASA has actually designated peanuts as aerospace food, as well as eating peanut products commonly can relieve cardiovascular diseases, reduced blood lipids, as well as delay aging. Foods abundant in Resveracel, such as peanut oil and peanut butter, will certainly become the brand-new style of nutrients as well as also wellness in the 21st century. Resveratrol is not only a chemopreventive agent for development diseases, nevertheless additionally a chemopreventive agent for lowering platelet gathering, staying clear of and also taking care of atherosclerosis, as well as cardio and cerebrovascular problems. Resveratrol has repressive results on Staphylococcus aureus, catarrhal germs, Escherichia coli, Pseudomonas aeruginosa, and additionally has solid repressive results on orphan infection, herpes simplex infection in addition to enterovirus, Coxsackie a, b group.
In the 1990s, Chinese clinical and also technological workers remained to deepen their research on resveratrol, and also disclosed its medicinal effects: inhibiting unusual gathering of platelets, preventing myocardial infarction and also analytical embolism, safeguarding the hypoxic heart, and also treating burns or blood loss. It can effectively recuperate the lowered cardiac output caused by shock, expand arteries and also improve microcirculation.
Resveracel is an anti-free radical, anti-oxidant, and also the features associated with it are as follows:
1. Postpone aging;
2. Protect against the oxidation of low-density lipoprotein, which has the potential to stop as well as treat cardiovascular diseases (atherosclerosis and also coronary heart problem, ischemic heart disease, hyperlipidemia, and so on);.
3. Influence lipid and also arachidonic acid metabolic process;.
4. Antithrombotic as well as antiplatelet aggregation;.
5. Anti-inflammatory as well as anti-allergic impacts.

Extraction of Resveracel From "Knotweed"

Polygonum cuspidatum is the root of Polygonum cuspidatum. Primarily created in Jiangsu, Zhejiang, Anhui, Guangdong, Guangxi, Yunnan, Sichuan, Guizhou as well as likewise other locations. The beginnings are removed in spring along with autumn, the rugged origins are removed, cleaned as well as dried in the sun.

Polygonum cuspidatum origins and likewise rhizomes contain free anthraquinones along with anthraquinone glycosides, primarily emodin, emodin methyl ether, chrysophanol, anthraglycoside A, anthraglycoside B, and more. It similarly includes resveratrol, resveratrol glycosides, protocatechuic acid, d-catechin, cassia anthrone-8-glucoside, β-sitosterol glucoside as well as also sugar, rhamnose, ginger sugar, Amino acids, tannins and likewise copper, iron, manganese, zinc, potassium as well as additionally potassium salts, and so on.

Resveratrol (Res), a nonflavonoid polyphenolic substance, is considered a phytoalexin that is developed when plants are struck by virus as well as additionally by ecological wear and tear. It mostly exists in 72 types of plants belonging to 12 family members as well as 31 genera such as grapes, knotweed, peanuts, mulberries, evergreen, maima creeping plants, and also Asian pagoda tree.

All-natural plant removal method: take Polygonum cuspidatum as basic material, eliminate along with separate the unrefined Res from it, and after that clean it. Rough removal techniques mostly include organic solvent removal, alkali elimination as well as also enzyme elimination, and additionally new approaches such as microwave-assisted removal, co2 supercritical extraction, as well as ultrasonic-assisted removal are additionally made use of. The purpose of purification is usually to split the cis in addition to trans isomers and also resveratrol glycosides of resveratrol in the eliminated Res raw item to obtain trans-resveratrol. Generally taken advantage of filtration approaches contain chromatography, silica gel column chromatography, thin-layer chromatography, as well as also high-performance liquid chromatography.

Resveracel has considerable antioxidant activity on both animal and also veggie oils. Amongst the 3 oil samples with resveratrol focus of 120, 240, in addition to 360mg/kg, the 240mg/kg oil example revealed the very best antioxidant task. In the antioxidant evaluation of lard, resveratrol The antioxidant impact of tea is a lot more effective than that of tea polyphenols with the same focus.

About Products:
If you need Resveracel, a cosmetic raw material, please contact our service staff directly, and we will provide you with high-quality products at the best price.
As an experienced manufacturer and supplier of Resveracel, ZSpharmac will provide Resveracel raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

OUR MISSION
Help China Chemicals to benefit the happiness of human life
OUR VISSION
Become the most trusted chemical supplier in the world
OUR BUSINESS PHILOSOPHY
Striver – oriented, enrich employees, customer first, deep service, seek development
OUR VALUES
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.

Service

Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.

 

After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.

FAQ

Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.

 

HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?

You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.

Shipping

1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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