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Pyridoxine Liquid CAS 111-42-2

Molecular Formula: C8H11NO3

Formula Weight: 169.18

ZSpharmac: Pyridoxine Liquid Raw Material Supplier

Product Name: Pyridoxine Liquid
CAS No: 111-42-2
Purity: 99%

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Basic Info

Product Name:Pyridoxine Liquid
Other Names:Pyridoxine
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White to Off-White Solid
EINECS No.:200-603-0
Storage:Inert Atmosphere,2-8°C
Provide:Pyridoxine Liquid MSDS;
Pyridoxine Liquid COA

What is Pyridoxine Liquid?

Pyridoxine, also known as vitamin B6 or anti-pellagra vitamin, is commonly referred to as pyridoxine hydrochloride in its prepared form. It is a white to slightly yellow crystalline powder with a melting point of 204-206°C. This vitamin is soluble in water, ethanol, and acetone, and slightly soluble in ether. It has a sour and bitter taste, and is stable in air but gradually deteriorates when exposed to sunlight. Pyridoxine easily sublimates and turns reddish brown when reacting with ferric chloride.

Pyridoxine Liquid Property

Melting point 214-215 °C(lit.)
Boiling point 298.46°C (rough estimate)
density 1.2435 (rough estimate)
refractive index 1.5100 (estimate)
storage temp. Inert atmosphere,2-8°C
solubility H2O: 0.1 g/mL at 20 °C, clear, colorless
pkapKa 5.00(H2O t = 25.0 I = 0.15 (mixed)) (Uncertain)
form Solid
color White to Off-White


Clinical Application of Pyridoxine Liquid

(1) Emergency Medicine Application
Pyridoxine Liquid plays a crucial role in amino acid metabolism and is involved in the synthesis of the neurotransmitter gammaaminobutyric acid (GABA). It has detoxification and antispasmodic properties and has been increasingly used in emergency medical situations.

(2) Cardiovascular Disease Application
Pyridoxine Liquid may be beneficial for individuals with cardiovascular disease. Elevated levels of homocysteine (Hcy) in the blood can lead to damage to blood vessels and endothelial cells, increasing the risk of cardiovascular diseases. Pyridoxine Liquid can help in lowering Hcy levels.

(3) Gynecological Disease Application
Vitamin B6, a coenzyme involved in the synthesis of GABA and serotonin, can help in reducing nerve excitability and relaxing uterine muscles. It is effective in treating primary dysmenorrhea in women, with minimal side effects and cost.

(4) Treatment of Vitamin B6-Dependent Epilepsy
Children with pyridoxine-dependent epilepsy have a deficiency in vitamin B6 due to metabolic disorders. They require pharmacological doses of vitamin B6 throughout their lives as they are not responsive to traditional anti-epileptic medications.

(5) Sebaceous Gland Regulation
Pyridoxine Liquid can regulate the activity of sebaceous glands, making it suitable for use in facial cleansing and care products for oil control. It can also improve the condition of oily hair and promote healthy hair follicles in hair care products.

(6) Other Applications
Vitamin B6 has been used in the treatment of carpal tunnel syndrome, childhood autism, acne vulgaris, and leukopenia. It can also prevent hand-foot syndrome associated with the use of capecitabine.

Pyridoxine Liquid Preparation

Pyridoxine Liquid is a common form of vitamin B6 found in nature and is widely used in vitamin supplements. The main method for producing pyridoxine hydrochloride in industry is the oxazole method. However, this method uses a large amount of phosphorus pentoxide, which can lead to equipment damage, safety hazards, and environmental pollution issues.
To address these challenges, researchers have optimized the process by eliminating phosphorus pentoxide and using simultaneous esterification of alanine and oxalic acid to produce N-ethoxyoxalanine ethyl ester instead of N-formylalanine ethyl ester. Additionally, the phosgene-triethylamine system is now used as an important intermediate in the production of cyclizing agents.
In 2009, further process improvements were made to simplify the synthesis of 4-methyl-5-ethoxyoxazole without the need for high vacuum distillation. This involved Diels-Alder cycloaddition with diethyl maleate, aromatization, and reduction to achieve a total yield of 56%.
One major drawback of these processes is the use of toxic benzene as a solvent. In 2003, Roche (Shanghai) Vitamin Co., Ltd. made a significant breakthrough by building a production line for vitamin B6 that does not rely on benzene as a solvent. This innovative approach has had a positive impact on environmental protection efforts in the vitamin B6 production industry.


Contact Us

As a company specializing in the production and supply of Pyridoxine Liquid raw materials, we are committed to providing customers with high-quality products and preferential prices. We have rich experience and technology to ensure product quality and stable supply. No matter where you are, we can provide you with the Pyridoxine Liquid raw materials you need to support your production and research and development.

We always adhere to the principle of honest operation, strictly control product quality, and serve every customer with a customer-first attitude. Over the years, we have established good cooperative relationships with customers at home and abroad and won their trust and praise.

If you have needs or are interested in our products, please contact our service staff directly, we will wholeheartedly provide you with the best quality services and products. Looking forward to cooperating with you and developing together!

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Pyridoxine Liquid Quotation