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Zhishang Chemical

Pyridoxine Hydrochloride Deutsch CAS 58-56-0

Molecular Formula: C8H12ClNO3

Formula Weight: 205.64

ZSpharmac: Pyridoxine Hydrochloride Deutsch Supplement

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Product Name: Pyridoxine Hydrochloride Deutsch
CAS No: 58-56-0
Purity: 99%

Basic Info

Product Name:Pyridoxine Hydrochloride Deutsch
Other Names:Pyridoxine Hydrochloride
CAS:58-56-0
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Food Additives
Appearance:White to Almost White Crystalline Powder
EINECS No.:200-386-2
Storage:Room Temp
Provide:Pyridoxine Hydrochloride Deutsch MSDS;
Pyridoxine Hydrochloride Deutsch COA

What is Pyridoxine Hydrochloride Deutsch?

Pyridoxine Hydrochloride Deutsch, also known as pyridoxine or anti-pellagra vitamin, scientific name 2-methyl-3-hydroxy-4,5-dihydroxymethyl pyridine, common name pyridoxine hydrochloride, usually used as its hydrochloride For the preparation, white or slightly yellow crystalline powder, melting point 204-206 ℃ (decomposition). It has a sour and also bitter taste, is steady in the air, adjustments in top quality when revealed to sunlight, as well as is simple to sublime. It is utilized for the avoidance and also therapy of pregnancy vomiting, radiation illness throwing up, isoniazid poisoning and also stomach reactions of antitumor drugs, and often additionally made use of as adjuvant treatment for pellagra and various other lack of nutrition.

Pyridoxine Hydrochloride Deutsch Properties:

Melting point 214-215 °C(lit.)
density 1.2784 (rough estimate)
vapor density 7.1 (vs air)
refractive index 1.5800 (estimate)
Fp 9℃
storage temp. room temp
solubility H2O: 0.1 g/mL at 20 °C, clear, colorless
form Crystalline Powder
color White to almost white
PH Range3.2
Water Solubility 0.1 g/mL (20 ºC)

 

Pyridoxine Hydrochloride Deutsch Uses

  1. Pyridoxine Hydrochloride Deutsch biochemical research and drug research, clinical drug belongs to vitamin B group, used for the treatment of pellagra, pregnancy vomiting, peripheral neuritis caused by isoniazid embolism.
  2. Pyridoxine Hydrochloride Deutsch is a vitamin medicine that can clinically deal with different diseases brought on by lack of VB6, such as leprosy and seborrheic dermatitis.
  3. Pyridoxine Hydrochloride Deutsch stipulates that vitamin B6 can be used in fortified solid beverages, with a maximum dosage of 7-10 mg/kg; in fortified infant food, the maximum dosage is 3-4 mg/kg; in fortified beverages, the maximum dosage is 1-2 mg/kg.
  4. Pyridoxine Hydrochloride Deutsch This product is mostly used as medicine, or to further synthesize drugs such as pyridoxine phosphate and brain rejuvenation. It is also utilized as feed additive, artificial additive, and is also included in cosmetics as an ultraviolet absorber.

Pyridoxine Hydrochloride Deutsch Pharmacological Actions and Applications

Pyridoxine Hydrochloride Deutsch reacts with ATP in the body to generate physiologically active pyridoxal phosphate and pyridoxamine phosphate. It is a coenzyme of aminotransferase, decarboxylation and racemase of certain amino acids and participates in many metabolic processes. . It is suitable for the prevention and treatment of pyridoxine deficiency, prevention and treatment of isoniazid and cycloserine poisoning; it can also be used for vomiting and seborrheic dermatitis caused by pregnancy, radiation sickness and anticancer drugs. It can also reduce the toxicity of colchicine.
(1) Application in emergency medicine
Pyridoxine is involved in amino acid metabolism and is related to the synthesis of the central neurotransmitter gamma-aminobutyric acid (GABA). On the basis of comprehensive treatment, the new therapy of high-dose pyridoxine combined with 20AA compound amino acids has achieved good curative effect in the treatment of hemorrhagic patients with rat poisons such as bromdiolone and tetramine, and trauma-induced coagulation disorders. . Intravenous infusion of large doses of pyridoxine can significantly improve the total effective rate of treatment of children with convulsions, so it is worthy of clinical promotion. Tuberculosis patients treated with isoniazid. If pyridoxine is not used at the same time, it may cause isoniazid poisoning, which is characterized by typical symptoms of pellagra, typical skin diseases of common diseases, and symptoms of intestinal diseases; for acute and severe isoniazid poisoning, intravenous injection can also be used Treatment with high-dose pyridoxine. In addition, high-dose vitamin B6 supplementation (50-100 mg/d) can improve the immune response level of critically ill patients.
(2) Application in cardiovascular disease
Pyridoxine is beneficial for some patients with cardiovascular disease. Homocysteine ​​(Hcy) is an intermediate metabolite of methionine metabolism. When the level of Hcy in plasma is abnormally elevated, it can damage endothelial cells and blood vessels, and is a risk factor for various cardiovascular diseases. Pyridoxine can promote the biosynthesis of nitric oxide (NO) in endothelial cells and reduce the level of Hcy in plasma. It is often combined with folic acid to treat homocysteinemia and accompanying coronary heart disease, hypertension, brain A series of cardiovascular and cerebrovascular diseases such as infarction.
(3) Application in gynecological diseases
Pyridoxine is a coenzyme for the synthesis of GABA and serotonin, which can reduce nerve excitability and relax uterine smooth muscle, so it can effectively treat female primary dysmenorrhea, and has the advantages of small side effects and low cost. Pyridoxine is also often combined with other drugs into compound preparations, such as Diclegis (doxylamine succinate-Pyridoxine Hydrochloride Deutsch, an oral sustained-release tablet) effective for nausea and vomiting in pregnant women, with good tolerance. acceptability. High-dose pyridoxine can also change local circulatory disorders, reduce milk production in lactating women, and can be used for breastfeeding or relieving acute mastitis. In addition, pyridoxine also has a certain therapeutic effect on gynecological diseases such as premenstrual syndrome and hyperprolactinemia perimenopausal syndrome.
(4) p-pyridoxine
Treatment of Dependent Epilepsy Pediatric pyridoxine-dependent epilepsy is a pyridoxine deficiency caused by inborn errors of metabolism. Children are not sensitive to conventional antiepileptic drugs and need to take pharmacological doses of pyridoxine for life. Children can take 25-200 mg/d of pyridoxine orally, and the maximum recommended dose is 500 mg/d. Pyridoxal-5-phosphate can be used for treatment of pyridoxine-dependent epilepsy in patients with pyridoxine-dependent epilepsy who do not respond to pyridoxine.
(5) Others
There are still reports of pyridoxine being used in the treatment of carpal tunnel syndrome, childhood autism, acne vulgaris, and leukopenia. Vitamin B6 also prevents capecitabine-induced hand-foot syndrome].

Is Pyridoxine Hydrochloride Deutsch Toxic?

Overdose of B vitamins can damage the liver:

Other brands of whitening pills generally do not contain Indoki-noki extract, and the price is relatively affordable. After we checked the composition of other brands of whitening pills, we found that in addition to the two conventional ingredients of vitamin C and vitamin E, they are also inseparable from the following two active ingredients: L-cysteine ​​and B vitamins.

White Rabbit Whitening Pills and Fancl Whitening Pills contain L-cysteine, which helps the body synthesize glutathione. It can maintain the normal metabolism of the skin, reduce the production of melanin, and is an effective whitening ingredient. But only people who are deficient in L-cysteine ​​in the body can help, and people who are not deficient in this substance have no effect.

Some ingredients may sound unfamiliar to everyone, such as vitamin B2, niacinamide, pyridoxine hydrochloride, calcium pantothenate, and tranexamic acid, which are all B vitamins. Pyridoxine hydrochloride is B6, calcium pantothenate is B5, and niacinamide is B3… B vitamins can promote our metabolism and are indispensable substances in the body, but taking too much may also damage the liver. There are also vitamin C and vitamin E in the whitening ingredients. The upper limit of oral vitamin C is 1000 mg. If you take vitamin C supplements in large doses for a long time, it may increase the risk of stones and hemolysis.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Our Mission
Help China Chemicals to benefit the happiness of human life
Our Vission
Become the most trusted chemical supplier in the world
Our Business Philososphy
Striver – oriented, enrich employees, customer first, deep service, seek development
Our Values
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.

Service

Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.

 

After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.

FAQ

Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.

 

HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?

You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.

Shipping

1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Pyridoxine Hydrochloride Deutsch Quotation