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Pyridine Solvent CAS 110-86-1

Molecular Formula: C5H5N

Formula Weight: 79.1

ZSpharmac: Pyridine Solvent Cosmetic Raw Material Suppliers

Product Name: Pyridine Solvent
CAS No: 110-86-1
Purity: 99%

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Basic Info

Product Name:Pyridine Solvent
Other Names:Pyridine
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Colorless Liquid
EINECS No.:203-809-9
Storage:Store at +5°C to +30°C.
Provide:Pyridine Solvent MSDS;
Pyridine Solvent COA

What is Pyridine Solvent?

Pyridine (molecular formula C6H5N) is a six-membered heterocyclic substance having a nitrogen heteroatom, that is, a compound in which one -CH= in the benzene particle is transformed by nitrogen. It resembles benzene, has the exact same digital framework, and also is still fragrant, so Similarly referred to as azobenzene as well as azabenzene, it is an anemic fluid with a special scent at location temperature, with a melting point of -41.6 ° C as well as a boiling point of 115.2 ° C. It develops an azeotrope with water along with has a boiling point of 92 to 93 ° C. (Industrial use this residential property to cleanse pyridine), density 0.9819 g/cm3. Conveniently soluble in a lot of natural solvents such as water, ethanol, and ether, in addition to can furthermore be made use of as a solvent itself. Pyridine was originally separated from bone tar, as well as likewise later it was discovered that coal tar, coal gas, shale oil, and additionally petroleum also include pyridine and additionally its homologues, such as 2-methylpyridine and also 2,6-dimethylpyridine.
Pyridine and also its byproducts are additional stable than benzene and likewise have similar reactivity to nitrobenzene. Because of the electron-withdrawing result of nitrogen atoms in the ring, the electron density at setups 2, 4, and also 6 is less than that of settings 3 as well as additionally 5. Normal fragrant electrophilic alternative actions happen at placements 3 in addition to 5, nonetheless their level of sensitivity is less than that of benzene. Reduced, typically not susceptible to nitration, halogenation, sulfonation and various other reactions. Additionally, these alternative responses are accomplished in acidic media, and pyridine types favorably billed ions, making electrophiles a lot less offered. The halogen of either 2- or 4-halopyridine is receptive. Because of the low electron density at positions 2 as well as likewise 6, nucleophilic replacement reactions can happen at these settings, such as response with salt amide or potassium hydroxide to obtain the corresponding 2-aminopyridine or 2-hydroxypyridine.

Pyridine Solvent Property

Melting point 

-42 °C (lit.)

Boiling point 

115 °C (lit.)


0.978 g/mL at 25 °C (lit.)

vapor density 

2.72 (vs air)

vapor pressure 

23.8 mm Hg ( 25 °C)

refractive index 

n20/D 1.509(lit.)


68 °F

storage temp. 

Store at +5°C to +30°C.


H2O: in accordance


5.25(at 25℃)






8.81 (H2O, 20℃)


Nauseating odor detectable at 0.23 to 1.9 ppm (mean = 0.66 ppm)

Relative polarity


Odor Threshold


Odor Type


explosive limit


Water Solubility 



Pyridine Solvent Uses

  1. Pyridine Solvent is mainly taken advantage of as a resources in the pharmaceutical market, as a solvent and alcohol denaturant, as well as furthermore in the production of rubber, paint, material along with rust preventions.
  2. Pyridine Solvent is a basic material for herbicides, chemicals, medicines, rubber accessories, and also fabric devices.
  3. As a solvent, pyridine can additionally be made use of in industry as a denaturant, coloring device, as well as also starting product for the synthesis of a collection of things, consisting of medications, anti-bacterials, dyes, food flavorings, adhesives, dynamites, and so forth.
  4. Pyridine Solvent is used as a solvent in natural synthesis. Moisture decision, stress mutagen. Solvent for acylation response. stimulant.
  5. Pyridine Solvent, as one of the essential nitrogen-containing heterocyclic substances, has really been commonly used in locations including photocatalysis and optoelectronic devices. In medical chemistry, pyridine is in addition often made use of as the moms and dad framework of drugs. Today, the deuteration response of pyridine mainly makes use of steel motorists such as Pd, Rh, Ir, Ru along with Ni to execute hydrogen isotope exchange (HIE) at the α-position, while HIE at other setups is rarely involved. Among the many derivatives of pyridine, some are crucial drugs, as well as some are essential components of vitamins or enzymes. For instance, the amide of pyridine-3-carboxylic acid (ie nicotinamide) creates a crucial dinucleotide with adenine (see purine), ribose and additionally phosphate in coenzyme I. Isoniazid, a by-product of pyridine, is a dental anti-tuberculosis medication. 2-Methyl-5-vinylpyridine is an essential raw material for fabricated rubber. Together with being used as a solvent, pyridine can additionally be made use of as a denaturant, tinting supporting agent, and also starting product for the synthesis of a collection of items in industry, consisting of pharmaceuticals, anti-bacterials, dyes, food seasonings, adhesives, nitroglycerins, etc.

Demand Analysis of Pyridine Solvent in Pesticides

In the field of agrochemicals, there is a chemical structure that can be seen almost anywhere, which is pyridine. Structurally, pyridine is a six-membered heterocyclic substance containing one nitrogen heteroatom. In terms of application, pyridine can be claimed to be an important intermediate that “sweeps” the 3 drugs (pesticides, drugs, and also vet drugs). It not only has a big market need, but additionally plays an exceptionally vital duty in advertising the green advancement of agrochemical and various other industries.
Pyridine pesticides, as the globe’s fourth-generation brand-new pesticides, have noticeable benefits. Pyridine ring-containing pesticides are not only highly effective, low-toxic, and long-lasting, however likewise have great ecological compatibility with people and also microorganisms, which is in line with the advancement demands and fads of chemicals. There are many types of pyridine unique great chemicals, amongst which chloropyridine is a high value-added product with fantastic growth capacity. Among them, the crucial intermediate in the manufacturing and also production procedure of the pesticide chlorpyrifos, which has a big market ability, is chloropyridine chemicals – 2,3,5,6-tetrachloropyridine. The crucial intermediate of imidacloprid, the first-generation star product of neonicotinoid insecticides, is also the chloropyridine item 2-chloro-5-chloromethylpyridine. In the field of herbicides, chloropyridines can be located all over. For instance, diquat is the 3rd biggest biocidal herbicide on the planet after glyphosate and paraquat. The crucial intermediate of this type of herbicide is the chloropyridine product 2-chloropyridine.
The role of chloropyridine is not limited to market, it can also be seen almost everywhere in everyday needs and medication. Chloropyridine can be made use of to produce the fungicide ZPT, which is extensively utilized in hair shampoos, consisting of Head & Shoulders, Rejoice as well as other well-known brand names including this ingredient. In the pharmaceutical area, chloropyridine is a crucial intermediate for medicines such as the antihistamine medication pheniramine, the main nerves stimulant medicine Ritalin, trazodone, as well as the antiarrhythmic drug disopyramide.

Pyridine Solvent Production Method

Pyridine Solvent was previously removed from coal tar. Coke oven gas was cleaned with sulfuric acid and also reduced the effects of with ammonia water to obtain unrefined light pyridine, which was after that purified by distillation. With the growth of the use of pyridine, the synthetic approach of pyridine has established substantially. Pyridine as well as pyridyl compounds gotten from coal tar abroad make up 10%. A mixture of acetaldehyde (1.648 mol), 37% formaldehyde (1.665 mol) as well as ammonia (3.096 mol) was responded at 432 ° C. The stimulant was SiO2-Al2O3-Bi2O3, and the pyridine yield was 48.4%. At the same time, β-methylpyridine is also generated. By changing the operating problems, the returns of pyridine, picoline and picoline can be changed. Additionally, pyridine can additionally be produced from 1,5-pentanediamine hydrochloride by heating for cyclization and dehydrogenation in the existence of Pt driver.

About Products:
If you need Pyridine Solvent, a cosmetic raw material, please contact our service staff directly and we will provide you with high-quality products at the best price.
As an experienced Pyridine Solvent manufacturer and supplier, our company, ZSpharmac will provide Pyridine Solvent raw materials to customers around the world for a long time.
Over the years, the company has adhered to the spirit of “integrity management, strict quality control, and customer first” and has won unanimous praise from customers at home and abroad.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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