1. Application in the field of cosmetics Generally speaking, the normal skin stratum corneum should retain 10% to 20% of moisture, so that the skin can be elastic, plump and shiny without cracking. The reason why a certain amount of water is retained in the stratum corneum is that, on the one hand, the sebum film has the ability to prevent water evaporation, and on the other hand, the stratum corneum contains natural moisturizing factors (NMF) with hygroscopic and moisturizing functions; sericin is rich in moisture. Contains polar amino acids, which contain polar groups such as -OH, -COOH, -NH2, and have similar ingredients and functions to moisturizing factors. Japan already contains sericin cosmetics, such as body lotion, facial cleanser, facial cleanser Wait. Studies have shown that the darkening of the skin is due to the oxidation of tyrosinase in melanocytes. Hideyuki Yamada’s research found that sericin can inhibit the activity of this enzyme and retain this ability after boiling. In sericin, tyrosine (Tyr), tryptophan (Trp) and phenylalanine (Phe) can absorb ultraviolet rays and prevent the skin from tanning and sunburn.
2. Application in the edible field More than 90% of the amino acids contained in sericin can be absorbed by the human body, and more than 17% of the amino acids contained in the amino acid are necessary for the human body. Among them, serine, glycine, and aspartic acid have special pharmacological effects: serine can effectively inhibit the increase of cholesterol in the blood, which can prevent and treat hypertension; inhibiting tuberculosis can be used to treat lung diseases. Glycine can reduce cholesterol at the same time, and has the effect of lowering blood sugar, preventing thrombosis, blood coagulation, and treating diabetes. Aspartic acid can reduce blood ammonia, protect the myocardium, treat angina pectoris, and also have a protective effect on the liver. Serine and glycine are also nutritional factors for glial cells, and sericin ingested (serine and glycine account for about half) can improve memory and prevent dementia. As an antioxidant, sericin can be used in the field of food, sericin can effectively inhibit fat peroxidation (food oxidation is mainly fat oxidation), and inhibit polyphenol oxidase, thereby inhibiting food browning. The study also found that Pure Sericin can promote the absorption of zinc, iron, calcium and other elements in mice.
3. In the field of fiber modification, the Pure Sericin is fixed on the surface of the fiber fabric through a cross-linking agent, so that the fiber has the original performance and the functional characteristics of Pure Sericin, which improves the wearability and value of the fabric. Polyester has high strength and good resilience, but it has poor moisture absorption and breathability, and poor wearing comfort, so it cannot be used as a better wearing fabric. Surface modification of polyester with Pure Sericin can improve the comfort of polyester.
4. Biomaterials Many studies have shown that Pure Sericin has the ability to act as a medical dressing. The water-absorbing properties of Pure Sericin help to maintain a relatively moist environment on the skin surface and can absorb exudate from wounds. Two-dimensional membranes and three-dimensional hydrogels and porous scaffolds prepared with sericin have been reported. In mouse experiments, not only as a dressing, but also as a Pure Sericin essence also showed very good wound healing properties and did not cause allergic reactions. Wounds treated with sericin exhibited less inflammatory responses compared to controls. In wounds treated with collagen and sericin, the epidermis of the Pure Sericin-treated group grew faster.