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Pure Luteolin CAS 491-70-3

Molecular Formula: C15H10O6

Formula Weight: 286.24

ZSpharmac: Pure Luteolin Supplier

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Product Name: Pure Luteolin
CAS No: 491-70-3
Purity: 99%

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Basic Info

Product Name:Pure Luteolin
Other Names:Luteolin
CAS:491-70-3
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Yellow Powder
EINECS No.:207-741-0
Storage:2-8°C
Provide:Pure Luteolin MSDS;
Pure Luteolin COA

What is Pure Luteolin?

Luteolin is an extremely representative all-natural flavonoid, which comes from weakly acidic tetrahydroxyflavonoids. It is extensively dispersed in the plant kingdom.In vegetables such as Brussels sprouts, cabbage, cauliflower, beetroots, broccoli, as well as carrots, as well as in the form of glycosides, it is distributed in celery, green peppers, perilla leaves, and also the fruit shell of Arachishypogaea, Ajugadecumbus, Lonicera japonica Thunb, Gentianopsis spaludosa, Valeriana amurensis Smir and also other plants. Pure luteolin is yellow crystalline powder.

Pure Luteolin Property

Melting point ~330 °C(lit.)
Boiling point 348.61°C (rough estimate)
density 1.2981 (rough estimate)
refractive index 1.4413 (estimate)
storage temp. 2-8°C
solubility Methanol (Slightly, Heated)
pka6.50±0.40(Predicted)
form powder
color yellow
Water Solubility Soluble in aqueous alkaline solutions (1.4 mg/ml), ethanol (~5 mg/ml), dimethyl sulfoxide (7 mg/ml), 1eq. Sodium hydroxide (5 mM), dimethylformamide (~20 mg/ml), water (1 mg/ml) at 25°C and methanol.

 

Pure Luteolin Pharmacology

1. Anti-tumor: The repressive result of Pure Luteolin on the expansion of lump cells is generally via preventing the activity of certain kinases in cells and obstructing the cell cycle.
2. Anti-oxidation: The anti-oxidation result of Pure Luteolin is mainly materialized in its own oxidation reaction as a lowering representative, which boosts the task of the antioxidant system of the microorganism.
3. Anti-inflammation: The anti-inflammatory task of luteolin is primarily manifested in its ability to decrease the task of inflammatory element transcription regulatory authorities and decrease the manufacturing of pro-inflammatory cytokines and also inflammatory moderators.
4. Neuroprotective result: Luteolin has a protective result on the discovering as well as memory capacity of the nerve system.
5. Anti-fibrosis: Luteolin can reduce the level of liver fibrosis, decrease the web content of hydroxyproline (HYP), malondialdehyde (MDA) in liver tissue as well as also the expression of kind I procollagen mRNA, and also can protect against the liver celebrity in vitro. Spreading as well as collagen synthesis of HSCs. It can in addition boost the histopathological changes of lung fibrosis brought on by bleomycin, decrease the lung weight index, substantially minimize the rise of MDA as well as HYP, and also prevent the expression of transforming advancement factor-β1 (TGF-β1) mRNA in lung cells, artificial insemination can inhibit the dispersing of human start lung fibroblasts as well as market their apoptosis.
6. Anti-fertility in addition to hormone effects: Pure Luteolin has considerable dose-dependent anti-implantation job. After dental monitoring, it can considerably boost the weight, diameter, density of the endometrium as well as also the height of its epithelial cells. It has estrogen-like results when applied alone. Hormonal agent impacts, yet when integrated with ethinyl estradiol, it has actually been revealed to have anti-estrogenic impacts.
7. Others: Luteolin can stop a selection of bacteria and also infections, such as Staphylococcus aureus, Escherichia coli, herpes simplex infection, polio infection, Coxsackie B3 infection, and so on. It can inhibit the activity of HIV-1 integrase, along with has potential anti-HIV impact. Luteolin can bind to the S2 protein of severe intense respiratory problem (SARS) coronavirus, therefore impeding the infection from getting in host cells. Luteolin additionally has the result of withstanding Leishmania donovani, impeding the development of Leishmania donovani by avoiding the activity of topoisomerase and also topoisomerase. On top of that, luteolin likewise has the impact of immune guideline and more.

Purification Process of Pure Luteolin

About Products:
If you need Pure Luteolin, a cosmetic raw material, please contact our service staff directly, and we will provide you with high-quality products at the best price.
As an experienced Pure Luteolin manufacturer and supplier, ZSpharmac will provide Pure Luteolin raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

OUR MISSION
Help China Chemicals to benefit the happiness of human life
OUR VISSION
Become the most trusted chemical supplier in the world
OUR BUSINESS PHILOSOPHY
Striver – oriented, enrich employees, customer first, deep service, seek development
OUR VALUES
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.

Service

Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.

 

After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.

FAQ

Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.

 

HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?

You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.

Shipping

1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Pure Luteolin Quotation