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Pure Grape Seed Extract CAS 84929-27-1

Molecular Formula: C4H11NO2

Formula Weight: 105.14

ZSpharmac: Pure Grape Seed Extract Cosmetic Raw Material Supplier

Product Name: Diethanolamine Sigma
CAS No: 84929-27-1
Purity: 99%

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Basic Info

Product Name:Pure Grape Seed Extract
Other Names:Grape Seed Extract
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Brown-Red Powder
EINECS No.:284-511-6
Storage:Room Temperature
Provide:Pure Grape Seed Extract MSDS;
Pure Grape Seed Extract COA

What is Pure Grape Seed Extract?

Grape seed essence is a plant essence whose major component is proanthocyanidins. It is a brand-new kind of highly effective natural antioxidant removed from grape seeds that can not be manufactured in the body. It is among one of the most efficient plant-derived anti-oxidants uncovered up until now. 1. In vivo and artificial insemination examinations have actually revealed that the antioxidant effect of grape seed remove is 50 times more powerful than vitamin E and 20 times more powerful than vitamin C. It can properly get rid of excess totally free radicals in the human body, and has super anti-aging and anti-aging residential or commercial properties. The main functions of immunity consist of anti-inflammation, antihistamine, anti-allergy, anti-allergen, antioxidant, anti-fatigue, enhancing fitness, improving sub-health condition, postponing aging, boosting impatience, wooziness, and memory. Reduce signs and symptoms, beautify, promote blood flow, etc.
In Europe, grape seed is called “oral skin cosmetics”. Grape seeds are all-natural sun shields that avoid UV rays from harming the skin. The sunlight can eliminate 50% of human skin cells; however if you take grape seeds for defense, about 85% of skin cells can endure. Due to the fact that the proanthocyanidins (OPC) in grape seeds have a special fondness for the collagen and elastin fibers of the skin, they can protect them from damage.
Grape seed essence, as the major functional ingredient in Asian ladies’s cosmetics, prevents tyrosinase activity, feeds on cost-free radicals and minimizes melanin deposition and dermatitis. It has an astringent effect, tightens up the skin, and avoids the very early appearance of skin creases. Long-lasting usage can The skin is smooth, flexible, and has the function of improving and nourishing the skin.

Pure Grape Seed Extract Property


0.961g/cm3 at 20℃

vapor pressure 

0.003Pa at 60℃

storage temp. 

Inert atmosphere,Room Temperature


Soluble in DMSO




Pure Grape Seed Extract Benefits

1. Feed on cost-free radicals
Due to the numerous phenolic hydroxyl groups in the molecular framework, proanthocyanidins incorporate with free radicals to cause them to shed their capability to strike cells in the body without forming damaging hazardous materials that can activate domino effect, consequently lowering or Get rid of the harmful impacts of oxygen cost-free radicals on body cells and organs, hold-up aging and improve the body’s immunity. Experiments have actually revealed that the anti-free radical oxidation capability of proanthocyanidins is 50 times that of vitamin E and 20 times that of vitamin C. It has very solid in vivo task and is a globally identified natural antioxidant that can successfully scavenge complimentary radicals in the body.

2. Promote blood circulation
Proanthocyanidins can feed on totally free radicals in intercellular liquid and plasma, hinder the process of totally free extreme damages to capillary wall surfaces, enhance blood vessels, arteries and veins, effectively secure the blood flow system, and offer numerous body organs and cells with an adequate blood supply. In Europe, proanthocyanidins have actually been utilized in clinical treatments for decades in order to boost blood circulation, treat diabetic retinopathy, reduce edema and prevent varicose capillaries.

3. Protect the heart
Proanthocyanidins not only assist collagen fibers develop a cross-linked structure, however also aid restore damages caused by excessive cross-linking caused by injury and totally free radicals (too much cross-linking can suffocate and set connective cells), therefore assisting joints, arteries and various other cells (such as the heart) to maintain regular function. Proanthocyanidins additionally decrease swelling and aid arteries stand up to the attack of mutagenic factors that activate heart disease. Therefore, whether in regards to long-term or short-term impacts, proanthocyanidins are the most effective cardioprotective agents discovered so far.

Red wine is abundant in proanthocyanidins, and the French are famous for their love of alcohol consumption white wine, which is normally a must-have with meals. This is why “the French normally consume far more high-fat foods than Americans, however the French die from heart problem at a much reduced price than Americans.”

4. Anti-radiation
In modern culture, individuals are progressively exposed to radiation damage. The free radical theory of radiation damages believes that radiation can create the body to create a large number of responsive oxygen varieties. These highly reactive free radicals can harm mobile proteins, DNA, and organic membrane layers, creating cell peroxidation damages, uncommon cell function, cell cycle conditions, and A collection of pathological damages such as cell necrosis and apoptosis. Proanthocyanidins can properly preserve and enhance the function of the body’s immune body organs after radiation damages, thus boosting the body’s capability to resist radiation. Experimental information on the blood system, antioxidant system, and body immune system all show that proanthocyanidins have safety and corrective impacts on radiation damages.

5. Anti-inflammatory and anti-allergic
When the human body is inflamed, it launches a compound called histamine, which can induce conditions such as allergies, bronchial asthma, bronchitis, hay fever, rheumatoid arteritis, and sporting activities injuries. The anti-allergenic and anti-inflammatory capacities of proanthocyanidins are well documented. Proanthocyanidins have actually likewise been reported to boost joint inflammation in lots of people. Athletes appreciate proanthocyanidins because they make joints versatile, repair work collagen in connective cells, and decrease edema. The principle is that proanthocyanidins prevent the enzymes required to generate histamine, protecting against the production of histamine, thereby lowering inflammation. Proanthocyanidins are popular preventions of histamine, but they do not block various other enzymes.

Pure Grape Seed Extract Preparation

Record 1.
a) Evaluate the recommended amount of grape seed essence, crush it, pass it with a 100-mesh screen, and set aside;;

b) Evaluate the suggested quantity of maltodextrin and xylitol anhydride monooleate, grind it, include the grape seed remove symphonious a) while grinding, and proceed grinding to get the grinded product;

c) Grind the starch in the weight component, 55% of the microcrystalline cellulose in the weight part and the carrageenan in the weight part to get a second grinding product;

d) Mix the main grinding material and the auxiliary grinding product equally and powder to get crude particles;
e) Pass the crude particles with a 100-mesh screen to get fine fragments;
f) Mix the weight parts of silicon dioxide, magnesium stearate and the staying part of microcrystalline cellulose with the fine fragments equally and push them right into tablets to get the Pure Grape Seed Extract tablet computers of the present innovation.

Report 2.
Take the raw products of the adhering to formula and reserved

Pure Grape Seed Extract15g (based on pure item).

Lycopene 1g.

Vitamin Cellulose 80g.

Hydroxypropyl methylcellulose 4g.

Prepare the pellet formulation as complies with:.

( 1) Take the above formula quantity of grape seed essence and lycopene and add vitamin cellulose, grind it to a micronized level with a sphere mill, and mix well;.

( 2) Liquify hydroxypropyl methylcellulose in 75% ethanol service;.

( 3) Utilize the extrusion-spheronization technique to make pellets.

Contact Us

About Products:
If you need the cosmetic raw material Pure Grape Seed Extract, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced Pure Grape Seed Extract manufacturer and supplier, our company, ZSpharmac will provide Pure Grape Seed Extract raw materials to customers around the world for a long time.
Over the years, the company has adhered to the spirit of “integrity management, strict quality control, and customer first” and has won unanimous praise from customers at home and abroad.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Pure Grape Seed Extract Quotation