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Pure Ginkgo Biloba CAS 90045-36-6

Molecular Formula: N/A

Formula Weight: 0

ZSpharmac: Pure Ginkgo Biloba Supplier

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Product Name: Pure Ginkgo Biloba
CAS No: 90045-36-6
Purity: 99%

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Basic Info

Product Name:Pure Ginkgo Biloba
Other Names:Ginkgo Biloba Extract
CAS:90045-36-6
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White Powder
EINECS No.:289-896-4
Storage:2-8°C
Provide:Pure Ginkgo Biloba MSDS;
Pure Ginkgo Biloba COA

What is Pure Ginkgo Biloba?

Pure Ginkgo Biloba is an old along with primitive relict types that has actually broadened on the planet for around 200 million years as well as is described as a “living fossil”. China is the hometown of ginkgo. Presently, China’s ginkgo sources make up 70% of the world’s total amount. Ginkgo biloba is used in the folk as a Chinese organic medication. It was first seen in the “Daily Materia Medica” in the 14th century. It is normally made use of for cough, asthma as well as swelling.
Ginkgo is furthermore called duck feet, gongsun tree, and duck hand tree. It is a deciduous tree, up to 40m high. Trunk set up, bark grey. There are 2 type of branches, long as well as additionally short. The fallen leaves are gathered on the quick branches and alternating on the prolonged branches. The leaves are fan-shaped, 4 to 8 centimeters long and 5 to 10 cm substantial. The seeds of Pure Ginkgo Biloba are called ginkgo.
Ginkgo biloba is distributed at 19 ° 40-43 ° 40 north latitude, 97 ° 00-126 ° 30 east longitude, with a common annual temperature level of 14 ° C-18 ° C, cool in wintertime and also spring, and likewise comfortable and damp in summertime as well as fall. Listed below -20 ° C) are prone to cool damage, as well as grow incorrectly in the tropics where there is regularly summertime period in addition to no winter season. Pure Ginkgo Biloba is extensively spread in my nation, from main to western my country, from Liaoning in the north, to Guangdong in the south, to Taiwan in the eastern, and likewise to Qinghai in the west. Most of them are Jiangsu, Shandong, Zhejiang, and Hubei, and also currently Japan and also the United States are likewise presented.
Ginkgo biloba extract is the dried leaf essence of Ginkgo biloba L., a plant of the category Ginkgo biloba. Its main parts are flavonoids and also terpene lactones. It has various health and wellness features and is extensively used in food and cosmetics.

Chemical Composition of Pure Ginkgo Biloba

The chemical make-up of Pure Ginkgo Biloba is incredibly complicated, along with there are above 140 compounds separated from it. Flavonoids and also terpene lactones are both significant active parts of Ginkgo biloba. Ginkgo flavonoids, in addition called solitary flavonoids, are mainly glycosides of kaempferenin, quercetin along with isorhamnetin; Esters as well as ginkgolides. In addition, it in addition includes polyprenol, organic acids, polysaccharides, amino acids, phenols and also trace elements.

 

Pure Ginkgo Biloba Uses

1. Advertise blood circulation
Pure Ginkgo Biloba can concurrently advertise blood circulation in the brain as well as body arm or legs, and manage blood vessel tone and flexibility. To put it simply, it can make blood vessel circulation extra effective, and also the renovation of flow performance acts upon big capillary (arteries) and also smaller blood vessels (capillaries) in the circulatory system.

2. Antioxidant effect
Pure Ginkgo Biloba has antioxidant properties on the brain, eye retina and also cardio system. Its antioxidant impacts in the brain as well as central nervous system can help stop age-related decreases in mind feature, consisting of diabetes mellitus and also macular deterioration (generally referred to as age-related macular degeneration or ARMD), Alzheimer’s illness.

3. Anti-aging function
Pure Ginkgo Biloba enhances blood circulation to the mind as well as is an exceptional tonic for the nerve system. Thousands of scientific studies entailing tens of thousands of clients have actually verified the effectiveness of ginkgo biloba essence for a selection of issues including inadequate blood circulation to the brain and psychological decrease in senior patients. Instances: Anxiety as well as anxiety, memory impairment, problem concentrating, decreased alertness, psychological decrease, vertigo, headache, tinnitus (ringing in the ear), macular degeneration (one of the most common cause of loss of sight in grownups), inner ear disturbance (other can create partial deafness), poor flow to the extremities, and erectile dysfunction as a result of bad blood flow to the penis.

4. Signs and symptoms of premenstrual discomfort
A double-blind regulated placebo study of Pure Ginkgo Biloba in women with premenstrual dysphoria. The trial consisted of 143 females aged 18-45 and also followed them for 2 menstruations. Each lady obtained Ginkgo extract (80 mg twice daily) or placebo on day 16 of the first cycle, therapy proceeded till day 5 of the next cycle, as well as on day 16 of the cycle restart. The outcomes go over. Compared with placebo, ginkgo dramatically lowered the primary signs of premenstrual dysphoria, particularly bust discomfort and state of mind swings.

Pure Ginkgo Biloba Physiological Activity

As early as the early 1960s, the remove of Pure Ginkgo Biloba has really been utilized abroad to take care of cerebrovascular ailment as well as additionally nerves problems, as well as additionally its medical effect is impressive without adverse impacts. Ginkgo biloba significance has a strong antioxidant impact, can remove excess cost-free radicals in the body, quit lipid peroxidation in the body, boost coronary vessels, rise analytical blood flow, increase platelet triggering component bitterness, as well as deal with vascular aging, cerebrovascular Not enough blood supply as well as also various other neurological health problem. Additionally, it in addition has the impacts of increasing the body’s resistance in addition to delaying aging.
1. The impact on the cardiovascular system
Pure Ginkgo Biloba can protect against the task of angiotensin-converting enzyme (ACE) in normal human product, as a result inhibiting the tightening of little arteries, expanding blood vessels, as well as likewise improving blood flow. Ginkgolide is an extremely specific PAF receptor blocker. Ginkgo biloba essence or ginkgolide can hinder platelet turning on element (PAF) in addition to cyclooxygenase or lipoxygenase. Ginkgo biloba get rid of was well endured in addition to annoyed platelet gathering caused by PAF, yet had no impact on celebration caused by ADP.
2. The result on the central nerve system
Ginkgo biloba essence influences the endocrine system and also the communication in between the body immune system in addition to the main nerve system by protecting against the effect of PAF, which can market mind flow metabolic rate as well as increase memory attribute. Along with boosting the absence of memory damage triggered by NaNO2, its anti-hypoxic outcome may be associated with enhancing logical blood circulation as well as boosting mind energy metabolism throughout hypoxia. Ginkgolide B can be used in the scientific therapy of stroke.
3. Results on the digestive system
Pure Ginkgo Biloba can significantly boost the tummy and also gastrointestinal abscess caused by PAF as well as endotoxin in rats, and additionally can partially inhibit the damages of ethanol to the stomach. Potential therapeutic impact on liver cirrhosis. Ginkgolide B may contribute in the therapy of severe pancreatitis.
4. The outcome on the respiratory system
The ethanol remove of Ginkgo biloba has a straight relaxing effect on tracheal smooth muscle mass. The inhalation of nebulized Ginkgo biloba extract not just prevents bronchoconstriction, nevertheless likewise inhibits the reduction of leukocyte as well as eosinophils caused by PAF. Ginkgo biloba significance has excellent value in preventing as well as also dealing with bronchial hyperresponsiveness.
5. Anti-aging impact
The ginkgobiflavones, isoflavones, ginkgoin and also quercetin in Pure Ginkgo Biloba all have the impact of impeding lipid peroxidation, especially quercetin has a much more powerful repressive job.
6. Obligation in transplant rejection as well as additionally different other immune actions
Ginkgo biloba remove prolongs the survival time of skin grafts, heterotopic heart xenografts, as well as orthotopic liver xenografts. Ginkgo biloba remove can avoid the body’s natural awesome cell activity versus KC526 target cells, and can furthermore prevent the natural incredible cell task caused by interferon.
7. Anti-tumor effect
The unrefined essence of Pure Ginkgo Biloba environment-friendly dropped leaves, especially the fat-soluble component, can avoid Epstein-Barr infection, heptadecene salicylic acid, biloxanthin (Bilo-betin) have solid inhibitory job; full flavonoids of Ginkgo biloba can raise the thymus Weight and also turf task degree, mobilize the body’s important anti-tumor ability; quercetin along with myricetin can avoid the occurrence of health hazards.
8. Antioxidant result
Pure Ginkgo Biloba significance can directly feed on lipid totally complimentary radicals, lipid peroxidation free radicals as well as likewise alkyl cost-free radicals, and more, and finish the cost-free radical cause and effect chain. At the same time, it can furthermore participate in controling and enhancing the activity of antioxidant enzymes such as superoxide dismutase and additionally glutathione peroxidase. The antioxidant outcome of flavonoids in EGB also surpasses that of vitamins, as well as also it has anti-free radical strike homes in vitro.

Extraction Method of Pure Ginkgo Biloba

According to insufficient data, the existing global standard Ginkgo biloba essence is EGb761 generated according to the German Schwabe trademarked procedure. Ginkgo biloba extract is a product extracted from the leaves of Ginkgo biloba L., as well as industrial essences are generally standard to include 24% flavonol glycosides and 6% ginkgo terpene lactones.
There are many techniques reported in the literature on the manufacturing process of Ginkgo biloba extract, mostly including acetone extraction-lead salt precipitation approach, ethanol extraction-macroporous resin adsorption separation approach, supercritical carbon dioxide extraction technique, alcohol extraction-extraction-chromatographic separation method, etc. The most commonly utilized technique in China is the ethanol extraction-resin separation method
The most extensively made use of technique in the house and abroad is natural solvent removal. Considering that other natural solvents are hazardous or volatile, ethanol is typically made use of as the removal agent. Experiments by Zhang Yonghong as well as others have actually revealed that the best conditions for drawing out flavonoids from ginkgo fallen leaves are 70% ethanol as the extraction remedy, the removal temperature is 90 ° C, the proportion of strong to fluid is 1:20, and the number of extractions is 3 times, each refluxing for 1.5 h.
1. Ethanol extraction-macroporous material adsorption separation technique
Pick out pollutants and also musty fallen leaves, laundry, chop, reflux with 70% ethanol to essence, separate the remove, filter, recoup ethanol under decreased pressure, high-speed centrifuge to get rid of slag, add proper amount of pure water to water down, add to macropore adsorption Resin column, eluted with water till the eluent is clear and light in color, then eluted with a certain focus of ethanol, gathered the eluate, focused under reduced stress, and dried in vacuum.
2. Acetone extraction-lead hydroxide precipitation technique.
Essence Pure Ginkgo Biloba with 60% acetone, filter after cooling down, remove the essence with carbon tetrachloride, add butanone and mix well, separate the acetone-butanone stage, include solid ammonium sulfate to the ketone phase and mix, filter For solid matter, vaporize the filtrate under decreased pressure to a concentration of 20%-60% of solid issue, as well as weaken with 50% denatured ethanol to a focus of 10% of solid issue. Include lead hydroxide suspension, and also filter off the precipitate. Focus the filtrate to half the quantity under reduced pressure, then include ammonium sulfate and butanone to the concentrated solution under stirring, and also precipitate the butanone-ethanol stage after the mixing is finished; different the butanone-ethanol stage from the water stage, and after that include it to the water stage Butanone was included in the mix, stirred, and also the butanone-ethanol stage was precipitated, which was incorporated into the above-mentioned butanone-ethanol stage. Add ammonium sulfate under mixing, divide the precipitated water stage after blending, completely dry the butanone-ethanol stage with sodium sulfate, evaporate to dryness under reduced pressure, liquify the denatured as well as viscous raffinate with denatured ethanol, and also area it for 12 hours to separate the precipitated precipitate. Evaporate under pressure and dry in vacuum.

About Products:
If you need Pure Ginkgo Biloba, the cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced Pure Ginkgo Biloba manufacturer and supplier, our company, ZSpharmac will provide Pure Ginkgo Biloba raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

OUR MISSION
Help China Chemicals to benefit the happiness of human life
OUR VISSION
Become the most trusted chemical supplier in the world
OUR BUSINESS PHILOSOPHY
Striver – oriented, enrich employees, customer first, deep service, seek development
OUR VALUES
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.

Service

Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.

 

After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.

FAQ

Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.

 

HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?

You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.

Shipping

1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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