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Zhishang Chemical

Pure Eugenol CAS 97-53-0

Molecular Formula: C10H12O2

Formula Weight: 164.2

ZSpharmac: Pure Eugenol Supplier

Product Name: Pure Eugenol
CAS No: 97-53-0
Purity: 99%

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Basic Info

Product Name:Pure Eugenol
Other Names:Eugenol
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Clear Pale Yellow to Yellow Liquid
EINECS No.:202-589-1
Provide:Pure Eugenol MSDS;
Pure Eugenol COA

What is Pure Eugenol?

Pure Eugenol normally exists in essential oils such as clove oil, clove basil oil and cinnamon oil. It is an anemic to pale yellow viscous oily liquid with a solid clove and also spice aroma.
Today, eugenol is produced industrially, as well as most of it is isolated from the vital oil abundant in Pure Eugenol by alkali treatment. Usually sodium hydroxide remedy is included in the apart oil, after heating as well as stirring, the oily compound of the non-phenolic component drifting on the liquid surface area is removed with solvent or steamed with water, and afterwards acid is added to acidify the sodium salt to obtain unrefined eugenol, Wash with water until neutral, and then vacuum cleaner distillation to acquire pure eugenol.
To prepare Pure Eugenol by synthetic approach, guaiacol can be utilized as resources, as well as allyl chloride, allyl alcohol, and so on can be used to directly allylate guaiacol to get (the previous Soviet license 352872; US patent 3929904).
When Pure Eugenol is prepared by artificial approach, there are several side reactions, that makes separation and purification challenging, and also influences item high quality, which needs to be improved and also improved in the future.
Pure Eugenol can be used in perfume significance and also numerous aesthetic significance as well as soap significance solutions, the dose is within 20%. Furthermore, it can likewise be made use of in food taste formulas. IFRA has no restrictions.

Pure Eugenol Property

Melting point 

-12–10 °C (lit.)

Boiling point 

254 °C (lit.)


1.067 g/mL at 25 °C (lit.)

vapor pressure 

<0.1 hPa (25 °C)

refractive index 

n20/D 1.541(lit.)


>230 °F

storage temp. 







pKa 9.8 (Uncertain)


Clear pale yellow to yellow

Water Solubility 

slightly soluble


Pure Eugenol Uses

  1. Pure Eugenol is a body scent developed with carnation blossoms. It is extensively used in aromatic great smelling as well as other scent kinds, can be used as modifier and also fixative, and can be used to add fragrance to colored soaps. Can be utilized in several floral scents such as roses. It can also be made use of in flavor, woody, oriental, and also incense flavors, along with edible flavor, mint, nuts, different fruit tastes, jujube flavors and also various other flavors as well as tobacco flavors.
  2. Pure Eugenol has a strong aroma of caryophyllales and also musk, and also it is the mixing base of Kangji scents. It is utilized in the mixing of cosmetics, soaps, as well as edibles. Eugenol has a strong antiseptic power, can be made use of as a regional analgesic for dental caries, and has a regional antiseptic result. Eugenol is the intermediate of a few other spices, by-products are isoeugenol, methyl eugenol, methyl isoeugenol, acetyl eugenol, acetyl eugenol, benzyl isoeugenol and so on. When eugenol is heated in potassium hydroxide, the double bond of the propenyl group undertakes rearrangement and also becomes an α-propenyl group conjugated with a benzene ring, therefore obtaining isoeugenol. After acetylation and also light oxidation, α- The cleavage of the propenyl group provides vanillin, which is the major part of an essential artificial flavoring agent. Eugenol can likewise be utilized to produce isoniazid, an unique drug for the therapy of consumption.
  3. Pure Eugenol is utilized to develop carnation-type tastes, isoeugenol and vanillin, etc. It is also utilized as a pesticide as well as chemical.
    Pure Eugenol is an edible seasoning defined in GB 2760-96. Mostly used for the preparation of tastes such as smoked ham, nuts and also seasonings. It is also the primary resources for the synthesis of vanillin.
  4. Pure Eugenol is an edible flavor allowed by my nation’s policies. It is primarily utilized to prepare mint, nut, spicy food flavors and cigarette tastes. The quantity made use of in meat is 40 ~ 2000mg/kg according to typical production requirements; 500mg/kg in sugar; 9.6-100mg/ kg in dressings; 33mg/kg in baked products; 32mg/kg in candy; 3.1 mg/kg in cold drinks; 1.4 mg/kg in soft drinks; 0.6 mg/kg in puddings. Additionally, eugenol has antibacterial impact and strong antiseptic power.
  5. Pure Eugenol is generally made use of for antibacterial, lowering high blood pressure.

How to Make Pure Eugenol

The main methods used in industry for the preparation of Pure Eugenol are isolation and chemical synthesis from natural essential oils. However, the isomers produced by chemical synthesis have very close boiling points and are extremely difficult to separate. In actual production, the separation method is the main method. The natural essential oil isolation method is based on the perennial subshrub clove basil as raw material, and the mixture of essential oil and water is obtained by steam distillation. Add 20% sodium hydroxide to the oil-water mixture, and then perform steam distillation to remove non-acidic substances.

At 50 ° C, the obtained Pure Eugenol sodium solution was added to 30% sulfuric acid and stirred to neutralize to Ph=2~3 (aqueous layer). After standing, the crude clove oil of the lower layer is separated, and the finished product of eugenol is obtained by distillation under reduced pressure. Or use essential oils containing a large amount of eugenol such as clove oil, add 30% sodium hydroxide solution, add inorganic acid or introduce carbon dioxide gas to make it precipitate. Or add it with sodium acetate, so that it can be freed and then steam distilled to obtain pure product.

A method for preparing eugenol from clove oil, characterized in that:

(1), will be pulverized to 5-10 object clove raw materials, add the extraction solvent of 10 times of amounts in extractor, temperature is controlled at 75-90 ℃, stirring and extracting 3 hours, totals 3 times;

(2), merge extract, after the solvent is recovered by concentrating under reduced pressure and vacuum, obtain dark brown clove oil;

(3), in clove oil, add the alkaline aqueous solution of 5 times of content 3-15%, after constant temperature 65-85 ℃ of stirring 3 hours, leave standstill layering, remove alkaline aqueous phase oil layer and collect for subsequent use;

(4), the alkaline water layer adds the activated clay of 5% of total volume, and after stirring 30 minutes, the activated clay is filtered and separated, and the acid solvent is gradually added in the filtrate, and the pH value is adjusted 6-7, and the eugenol is separated and separated out in the solution, and the lower layer is Eugenol oil layer;

(5), the eugenol oil layer collected is also washed with deionized water, and the eugenol after washing is distilled, and the slightly yellowish distillate collected is a pure eugenol oil product;

(6), Pure Eugenol oil product is dehydrated and dried to obtain a slightly yellowish eugenol product in chromaticity.

Nutrition Facts of Pure Eugenol

Cloves contain volatile oil that is clove oil. The key in the oil contains eugenol (72%-90% of the composition), acetyleugenol, B-germanisene, and its hydroxy-n-amyl ketone, methyl salicylate, humulene, benzaldehyde, benzyl Alcohol, m-methoxybenzaldehyde, benzyl formate, piperonol, alpha-ilanene, etc.

1. Anti-gastric ulcer: It can inhibit the production of experimental gastric ulcer in rats. The volatile oil of clove flower and eugenol can significantly increase the metabolism of gastric mucus, but the acid value does not increase. Eugenol may be a specific component of anti-ulcer.

2. Inhibiting intestinal excitement: its water decoction can inhibit the spontaneous contraction of paraffin sectioned rabbit intestines, and can resist the stimulating effects of acetylcholine and nitrosamines on paraffin sectioned intestines.

3. Anesthesia: Pure Eugenol has anesthesia effect on young grass shrimp, crucian carp, etc. Eugenol can inhibit the compound action potential of chemical fibers of sympathetic nerve A, B, and C in rats, which may be one of the mechanisms of lilac to discourage teeth. Pure Eugenol can block the nerve transmission of the lumbar vertebra of American frog, but does not affect the response of the muscle post-synaptic membrane, showing the effect of selectively anesthetizing the sympathetic nerve.

4. Antibacterial and antiviral treatment: Clove oil and Pure Eugenol have broad-spectrum antibacterial effects. The ellagitannins in cloves have anti-herpes simplex virus infection effects. Antifungal: Its decoction or alcohol extract has broad-spectrum antifungal effect, or kill effect. Pure Eugenol has obvious eradication effect on Candida albicans and Cryptococcus neoformans.

About Products:
If you need Eugenol, a cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced Eugenol manufacturer and supplier, ZSpharmac will provide Eugenol raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, and customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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