Zhishang Chemical

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Zhishang Chemical

Proteose Peptone CAS 73049-73-7

Molecular Formula: C13H24O4

Formula Weight: 244.32726

ZSpharmac: Proteose Peptone Supplier

Product Name: Proteose Peptone
CAS No: 73049-73-7
Purity: 99%

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Basic Info

Product Name:Proteose Peptone
Other Names:Peptone
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Dark Cream Powder
EINECS No.:615-895-9
Storage:Room Temp
Provide:Proteose Peptone MSDS;
Proteose Peptone COA

What is Proteose Peptone?

Peptone is a mix of peptones, peptides as well as amino acids with various degrees of hydrolysis, and is a thing acquired by hydrolyzing healthy proteins. Different pet dog as well as additionally plant healthy and balanced proteins can also be taken advantage of to make peptone. The common resources for the production of peptone is animal bone, however there are lots of sources for the manufacturing of peptone: pets blood provided by abattoirs; fish body organs given by water item taking care of manufacturing facilities; deposits after extracting body organ medications from biochemical pharmaceutical production centers; Glue slag after jelly production; steamed bone water and also fish recipe from bone grain manufacturing plant can be utilized as resources for egg white production. Nevertheless, the amino acid sort of fish protein are reasonably total, which is conducive to the development of microorganisms and also is an essential basic material for the production of peptone. Peptone is a vital element of microbial society medium and is extensively used in fermentation market, biochemical field and also biological reagents such as anti-biotics, amino acids, enzymes as well as nucleic acids. Biochemical reagent quality items are mainly utilized in clinical study, medical testing, commodity assessment, and so on. According to various sources of protein, it can be divided right into pet dog peptone, plant peptone, microbial peptone, and so forth. The medium composed of various peptones has considerable distinctions in the farming result of germs. According to numerous usages, peptone items can be split right into 3 teams: biochemical reagent peptone, commercial peptone as well as biochemical reagent peptone.

Proteose Peptone Property

storage temp. room temp
solubility H2O: 50 mg/mL
form powder
color Dark cream powder
PH6.5-7.5 (2% in H2O)
Water Solubility Soluble in water. Insoluble in alcohol.


Proteose Peptone Uses

  1. Proteose Peptone is an important element of microbial society tool and an excellent nitrogen resource for microbial growth. Widely made use of in fermentation markets such as prescription antibiotics, amino acids, enzymes, as well as nucleic acids. Biochemical reagent grade items are generally made use of in clinical research, clinical screening, product inspection, etc. It can treat digestive system diseases in medicine.
  2. Proteose Peptones are polypeptides containing amino acids, healthy proteins, as well as in many cases little carbohydrate chains. Making uses of peptones are cellular nourishment, visually they are utilized to build tissue, consequently enhancing muscular tissue dimension, and also some anti-aging therapies.

Proteose Peptone Preparation Method

(1) Raw materials Animal and plant cells with high protein content are superb resources for the manufacturing of Proteose Peptone. Most of the domestically produced peptones are made from bones and fascia left over from the production of canned food and also meat items in canneries as well as meat handling plants, and also fish ribs, low-value small garbage fish and fishmeal from the production of fish fillets in aquatic item processing plants. The continuing to be bean cakes (which can produce plant-based peptone) are used as raw materials when oil mills create oil.
When creating Proteose Peptone, the adipose tissue in the raw material should be eliminated to stop it from affecting the subsequent process as well as item top quality.
( 2) Hydrolysis Put 1000kg of fresh small miscellaneous fish into an acid and also antacid resistant reaction pot with a stirrer, warm and simmer for 1 hr. Let it cool to 45 ° C, add ammonia water to readjust the pH to 8-9, add 125kg of minced icy porcine pancreas, keep the temperature level at 45 ° C, continue hydrolysis for 7 hrs, after that raise the temperature to 50 ° C, continue hydrolysis for 2 hours, and the hydrolysis is primarily finished. Stir frequently during hydrolysis.
When inspecting whether the hydrolysis is total, take a little hydrolyzate, add hydrochloric acid to readjust the pH to 0.5, boil as well as filter, take 5ml of the filtrate, include 20ml of saturated zinc sulfate option, if there is a small amount of floc precipitated, it implies that the hydrolysis has been completed; if there is a huge quantity of floc If there is a form, it indicates that the hydrolysis is not total as well as needs to continue hydrolysis.
( 3) After the ammonia removal, neutralization and hydrolysis are completed, seal the response pot, heat it to 110-115 ° C, open the air launch shutoff, and also release the air to remove the ammonia for 2-2.5 hrs. After the ammonia elimination is finished, gradually include antarctic acetic acid while preserving a mild boiling state, and change the pH of the hydrolyzate to concerning 5.5. Warmth as well as boil for 15 mins, great and also let stand for 12 hours. Siphon the supernatant, filter it with a nylon bag, and gather the filtrate. Include water twice the quantity of the deposit to the filteringed system residue, warm and boil for 15 mins, and filter. The 2nd filtrates were combined.
( 4) Eliminate tyrosine and contaminations. Pump those filtrate into the focus pot. When the vacuum level is not less than 90kPa as well as the temperature is not greater than 80 ° C, when it is focused to a viscous state, put it into a barrel and also send it to below 0 ° C. Location it in the fridge for 2 days to separate out the tyrosine and fat in the concentrate. Eliminate the drifting fat layer from the cold-treated focused solution, add water to thin down to 12 ° Bé, and after that make use of a centrifuge to get rid of tyrosine, and then filter the centrifuged service to information by vacuum cleaner filtering.
( 5) Elimination of fundamental protein Pump the filtrate into a pressure cooker, change the pH to 9.2 with ammonia water, warm to 120 ° C for 10 minutes, cool down to 10 ° C with water, and filter under lowered pressure to eliminate standard healthy protein. The filtrate after elimination of standard healthy proteins have to be cleared up.
( 6) Concentrate and completely dry. Heat the filtrate to bring it to a slight boil up until it is concentrated to 15 ° Bé. The focused service is dried with a call vacuum cleaner stove or a spray clothes dryer. The benefit of using a vacuum cleaner drying out oven for drying out is that the drying out is performed at reduced temperature, which can prevent the product from overheating and is much less contaminated by air. Its disadvantage is that it can not be generated constantly, the labor intensity is high, and the product color is dark. The benefits of spray drying out are: quick drying out speed, constant automated production, reduced labor intensity, and light item shade. Its drawbacks are: large equipment investment and high energy intake. When spray drying, the feed fluid have to be pre-heated before spray drying out to release the air in the feed liquid to make the tissue compact as well as heavy powder, otherwise the quantity of the product will certainly raise and the output will certainly be influenced.
( 7) Product Packaging Vacuum-dried Proteose Peptone is in the form of a block, which is ground by a ball mill prior to packaging; spray-dried peptone remains in powder kind and also can be straight packaged in brown glass or plastic containers.

Proteose Peptone Commonly used in Microbial Culture Media

Generally, peptone is obtained by digesting animal tissues with pepsin or trypsin. Currently the most used bovine peptone.

Casein peptone
Also known as: casein, casein, milk casein, tryptone.

It is a peptone obtained by hydrolyzing casein with trypsin. It has relatively complete amino acids, especially a relatively high content of tryptophan. It is suitable for indigo matrix and sugar fermentation experiments, but it lacks sulfur-containing amino acids such as cystine and methionine, so it is not suitable for use. in the hydrogen sulfide test. Casein is a phosphorus-calcium-binding protein that is acid-sensitive and precipitates at lower pH. Casein is the major protein in mammalian milk, including bovine, ovine, and human.

Polyvalent peptone
Peptone is a mixture of equal amounts of casein peptone and bacto-peptone. Suitable for general bacterial culture and reproduction.

Beef peptone
Peptone obtained from trypsin digestion of fresh beef. Rich in amino acids, growth-promoting factors, etc., the nutritional content is higher than that of bacto-peptone.

The product of low-level digestion of casein by trypsin can be partially precipitated by ammonium sulfate. Rich in a large number of low molecular weight peptides, free amino acids and growth-promoting factors, without para-aminobenzoic acid, it is suitable for the preparation of bacterial toxin-producing media.

Soy peptone
It is a hydrolyzate obtained by papain digestion of soybean flour, which is high in vitamins, especially thiamine (vitamin B1), and contains a lot of carbohydrates. It is an excellent peptone without animal origin, suitable for fungi and many nutritional requirements Bacteria with high concentration are not suitable for microbial sugar alcohol fermentation test. Generally, it works better when mixed with other types of peptones.

Acid Hydrolyzed Casein
It is a white or light yellow powder made of high-quality casein as raw material, deeply hydrolyzed with strong acid, decolorized, desalted, concentrated, and spray-dried. Most of the vitamins are hydrolyzed by strong hydrochloric acid, lacking cystine and tryptophan. It is suitable for the medium for drug susceptibility test and the medium for vitamin determination by microbiological method.

Gelatin peptone
It is a product of trypsin hydrolysis of gelatin. Low in cystine and tryptophan, no carbohydrates. Especially suitable for microbial sugar alcohol fermentation test.

About Products:
If you need Proteose Peptone, a cosmetic raw material, please contact our service staff directly, and we will provide you with high-quality products at the best price.
As an experienced Proteose Peptone manufacturer and supplier, ZSpharmac will provide Proteose Peptone raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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