Zhishang Chemical

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Zhishang Chemical

Propylene Glycol Usp CAS 57-55-6

Molecular Formula: C3H8O2

Formula Weight: 76.09

ZSpharmac: Propylene Glycol Usp Supplement

Product Name: Propylene Glycol Usp
CAS No: 57-55-6
Purity: 99%

Basic Info

Product Name:Propylene Glycol Usp
Other Names:1,2-Propanediol
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Colorless Viscous Liquid
EINECS No.:200-338-0
Storage:Store at +5°C to +30°C.
Provide:Propylene Glycol Usp MSDS;
Propylene Glycol Usp COA

What is Propylene Glycol Usp?

Propylene Glycol Usp has excellent solubility, less toxicity and irritability, as well as is extensively used as shots (such as intramuscular shots, intravenous shots) and also non-injectable pharmaceutical preparations (such as oral fluids, ocular preparations, ear prep work, dental preparations, rectovaginal prep work) It is a far better solvent than glycerin and can liquify several substances such as corticosteroids (sex hormonal agents), chloramphenicol, sulfonamides, barbituric acid Salt, reserpine, quinidine, dehydrocorticosterone acetate, fumarate sulfate, nitrogen mustard hydrochloride, vitamin A, vitamin D, many unpredictable oils, a lot of alkaloids, and lots of anesthetics.

Propylene Glycol Usp resembles ethanol as a bacteriostatic representative, and its efficacy in hindering mold is similar to that of glycerin, however a little less than that of ethanol. Propylene Glycol Usp is commonly made use of as a plasticizer for liquid movie finishes. The very same quantity of blended service with water can postpone the hydrolysis of some medications and also raise the security of the preparation product.15%~30% Propylene Glycol Usp solution and semi-solid preparation can be used as antibacterial preservatives, about 15% propylene glycol topical preparation can be used as moisturizing agent, 10%~30% Propylene Glycol Usp aerosol solvent, 10%~25% % Propylene Glycol Usp oral solution, 10% to 60% of injection preparations, and 5% to 80% of topical preparations should be used as solvents and co-solvents.

[Stability and storage conditions] Extremely stable at room temperature, but oxidized when left open at high temperature (above 280°C); chemically stable after mixing with 95% ethanol or water; autoclaving or filtration sterilization bacteria. Propylene glycol is hygroscopic and should be stored in a cool, dry place, protected from light, in an airtight container. 【Incompatibility】There are incompatibility with certain oxidants (such as potassium permanganate).

Propylene Glycol Usp Properties:

Melting point -60 °C (lit.)
Boiling point 187 °C (lit.)
density 1.036 g/mL at 25 °C (lit.)
vapor density 2.62 (vs air)
vapor pressure 0.08 mm Hg ( 20 °C)
refractive index n20/D 1.432(lit.)
Fp 225 °F
storage temp. Store at +5°C to +30°C.
solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form Viscous Liquid
color APHA: ≤10
Specific Gravity1.038 (20/20℃)1.036~1.040
PH6-8 (100g/l, H2O, 20℃)
explosive limit2.4-17.4%(V)
Water Solubility miscible


Propylene Glycol Usp Uses

  1. Propylene Glycol Usp is used as raw material for material, plasticizer, surfactant, emulsifier and demulsifier, likewise as antifreeze and warm provider.
  2. Propylene Glycol Usp is used as gas chromatography fixative, solvent, antifreeze, plasticizer as well as dehydrating agent.
  3. Propylene Glycol Usp is utilized as carrier solvent; wetting agent; humectant; anti-caking agent; antioxidant; texturizing representative; surfactant; stabilizer; enlarging representative; dough conditioner; emulsifier; flavoring agent; excipient; Handling aids. GB2760 ~ 96 are noted as food processing aids. Primarily used as a solvent for different spices, pigments and also chemicals, as a removal solvent for vanilla beans, roasted coffee granules, all-natural spices, etc. Moisturizer and conditioner for candy, bread, packaged meat, cheese, and so on. It can also be used as an anti-mildew additive for noodles as well as packing cores. Adding 0.006% to soymilk can make the taste unmodified when warmed, and make white and also shiny packaged tofu, while frying will certainly boost the volume.
  4. Propylene Glycol Usp is an intermediate of the fungicide difenoconazole.
  5. Propylene Glycol Usp can be made use of as a solvent to dissolve preservative that are insoluble in water, such as chemicals, pigments, anti-oxidants, and so on, and afterwards contributed to food. It has strong hygroscopicity and has moisturizing and also antifreezing impacts on food. my nation states that it can be utilized in cakes, as well as the optimum use is 3.0 g/kg.
  6. Propylene Glycol Usp is a vital raw material for unsaturated polyester, epoxy material, and polyurethane resin. The usage in this respect accounts for regarding 45% of the overall consumption of propylene glycol. This unsaturated polyester is extensively utilized in surface finishings and also enhanced plastics. Propylene glycol has excellent viscosity and hygroscopicity, and also is non-toxic, so it is extensively utilized as a hygroscopic representative, antifreeze representative, lubricant and also solvent in the food, pharmaceutical and also cosmetic markets In the food market, propylene glycol as well as fats react to form propylene glycol fat esters, which are primarily used as food emulsifiers; propylene glycol is an exceptional solvent for spices as well as pigments. Propylene glycol is frequently used in the pharmaceutical industry as a solvent, softener as well as excipient for the manufacture of various ointments and lotions. Because propylene glycol has excellent shared solubility with various fragrances, it is also used as a solvent and softener for cosmetics. Propylene glycol is additionally utilized as a tobacco moisturizing agent, a mold inhibitor, a lubricant for food processing tools, and also a solvent for food marking inks. Liquid services of propylene glycol are effective antifreeze representatives.
  7. Propylene Glycol Usp is made use of as a medicine service provider and a granular pharmaceutical representative. It can be utilized as a cream, softener, solvent, etc in cosmetics. In the tobacco sector, it can be made use of as cigarette flavor, cigarette moisturizing agent, chemical, etc. In the food market, it is made use of as a solvent for flavor, food coloring, food product packaging conditioner, food anti-sticking agent, etc. It can additionally be utilized for the production of unsaturated polyester materials, in addition to plasticizers, dehydrating agents, surfactants, healing agents, and also raw materials for binders. Can likewise be used in paints, pesticides, finishes as well as other sectors.
  8. Propylene Glycol Usp Air Travel Deicing Fluids, Refrigerants & Antifreezes, Food & Fragrances, Fragrances, Cosmetics & Personal Wellness Products, Warmth Transfer Liquids, Hydraulic & Brake Fluids, Paints & Coatings, Animal Food/Animal Feed, Pharmaceuticals, Polyurethanes, unsaturated polyester material, etc.

Propylene Glycol Usp Production Method

It can be acquired by hydrolysis of propylene oxide:
direct hydration.
Propylene oxide as well as water are prepared in a molar ratio of 1:15, react at 150-200 ° C. and 1.2-1.4 MPa for half an hour to get a liquid remedy including 16% propylene glycol, and the ended up item is acquired by dissipation and also rectification.
The catalytic hydrolysis response is performed under the catalysis of sulfuric acid or hydrochloric acid. Add 0.5% -1.0% weaken sulfuric acid to 10% -15% propylene oxide liquid remedy, as well as hydrolyze at 50-70 ° C; the hydrolyzed solution is reduced the effects of, focused under reduced stress as well as refined to get the ended up product.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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