Propylene Glycol Usp has excellent solubility, less toxicity and irritability, as well as is extensively used as shots (such as intramuscular shots, intravenous shots) and also non-injectable pharmaceutical preparations (such as oral fluids, ocular preparations, ear prep work, dental preparations, rectovaginal prep work) It is a far better solvent than glycerin and can liquify several substances such as corticosteroids (sex hormonal agents), chloramphenicol, sulfonamides, barbituric acid Salt, reserpine, quinidine, dehydrocorticosterone acetate, fumarate sulfate, nitrogen mustard hydrochloride, vitamin A, vitamin D, many unpredictable oils, a lot of alkaloids, and lots of anesthetics.
Propylene Glycol Usp resembles ethanol as a bacteriostatic representative, and its efficacy in hindering mold is similar to that of glycerin, however a little less than that of ethanol. Propylene Glycol Usp is commonly made use of as a plasticizer for liquid movie finishes. The very same quantity of blended service with water can postpone the hydrolysis of some medications and also raise the security of the preparation product.15%~30% Propylene Glycol Usp solution and semi-solid preparation can be used as antibacterial preservatives, about 15% propylene glycol topical preparation can be used as moisturizing agent, 10%~30% Propylene Glycol Usp aerosol solvent, 10%~25% % Propylene Glycol Usp oral solution, 10% to 60% of injection preparations, and 5% to 80% of topical preparations should be used as solvents and co-solvents.
[Stability and storage conditions] Extremely stable at room temperature, but oxidized when left open at high temperature (above 280°C); chemically stable after mixing with 95% ethanol or water; autoclaving or filtration sterilization bacteria. Propylene glycol is hygroscopic and should be stored in a cool, dry place, protected from light, in an airtight container. 【Incompatibility】There are incompatibility with certain oxidants (such as potassium permanganate).
