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Zhishang Chemical

Propanoic CAS 79-09-4

Molecular Formula: C3H6O2

Formula Weight: 74.08

ZSpharmac: Propanoic Supplier

Product Name: Propanoic
CAS No: 79-09-4
Purity: 99%

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Basic Info

Product Name:Propanoic
Other Names:Propionic Acid
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Colorless Clear Oily Liquid
EINECS No.:201-176-3
Storage:Store Below +30°C.
Provide:Propanoic MSDS;
Propanoic COA

What is Propanoic?

Propanoic, also referred to as first oleic acid, is a saturated monocarboxylic acid containing 3 carbon atoms, among the common volatile reduced fats. Chemical formula CH3CH2COOH. Molecular weight 74.08. Anemic clear oily fluid with an unpleasant rancid pungent scent. Melting point -20.8 ° C, boiling point 140.99, 41.65 (1330Pa), relative density 0.9930, refractive index 1.3869. Ka=1.34 × 10-5. Miscible with water. Soluble in alcohol, chloroform and also ether. The chemical homes are energetic as well as acidic, as well as can undertake responses such as salt development, esterification, and reduction.

Propanoic Property

Melting point 

−24-−23 °C(lit.)

Boiling point 

141 °C(lit.)


0.993 g/mL at 25 °C(lit.)

vapor density 

2.55 (vs air)

vapor pressure 

2.4 mm Hg ( 20 °C)

refractive index 

n20/D 1.386(lit.)


125 °F

storage temp. 

Store below +30°C.


organic solvents: soluble(lit.)


4.86(at 25℃)




≤10, APHA:

Specific Gravity

0.996 (20/4℃)


3.96(1 mM solution);3.44(10 mM solution);2.94(100 mM solution);

Odor Threshold


explosive limit


Water Solubility 

37 g/100 mL



Propanoic Uses

  1. Propanoic helps reduce the look of hyperpigmentation. It lowers melanin manufacturing (the pigment in charge of skin shade as well as hyperpigmentation) by preventing the enzyme in charge of melanin production.
  2. Propanoic can be utilized in the food market to produce chemicals such as calcium propionate and also salt propionate, as well as can additionally be made use of to produce propionate tastes as well as fragrances.
  3. Propanoic is a crucial chemical resources. It is the fungicides metalaxyl as well as benalaxyl, the herbicides propanil, quizalofop, fenoxaprop, fluazifop, thiazoprop, haloxyfop, The intermediates of lactoforin, pretilachlor, napropamide, etc are also pharmaceutical intermediates, and can be utilized as preservatives in the food sector, fresh-keeping representatives for environment-friendly feed, and so on.
  4. Propanoic Determination of Aromatic Diamines, Gas Chromatographic Evaluation Criterion. Insect cell society grade is made use of to inhibit the development of mold in insect cell culture.
  5. Propanoic is used for (1) preservative. Calcium propionate as well as sodium propionate can stop food wasting due to the activity of microbes, lengthen food conservation time, and also work for the conservation of bread as well as bread. (2) Grain chemical. Propionic acid has actually been successfully used in the anti-mildew and also anti-caking of grains, which offers a brand-new technique for lasting storage space and conservation of grains. (3) Beverage preservative. Examinations have actually revealed that propionic acid, salt propionate, and also calcium propionate are all good feed preservatives, and also are mainly used to protect feed for pigs, livestock, lamb as well as chicken, among which calcium propionate has the best effect. Zinc propionate and cadmium propionate in propionates are drivers for polyester manufacturing of terephthalates; there are many selections of propionates with their own usages, and can be utilized as solvents, fragrances, pharmaceutical intermediates, cosmetics Additives, resin modifiers, cigarette filter plasticizers, gas oil antiknock agents, anti-bacterial agents, etc. The intermediates of propionic acid derivatives, 2-chloropropionic acid, lactic acid, 2,2-dichloropropionic acid, 2-bromopropionic acid, 3-chloropropionic acid, propionitrile, and also propionyl chloride, are used in many medicines, chemicals and also herbicides respectively The production of drugs, food fortifiers, seasonings and other products.

Propanoic Production Method

Propanoic exists in fermented or spoiled milk products, molasses and starch, etc. In the early days, propionic acid was mainly derived from the by-products of certain products, such as paraffin nitration, molasses or starch fermentation, wood dry distillation, and light hydrocarbon oxidation to acetic acid, all of which produced a small amount of propionic acid. At present, the methods for industrial production of Propanoic mainly include oxidation of propionaldehyde, carboxylation of ethanol, and oxidation of light hydrocarbons to produce acetic acid as by-product recovery.
1. Propanoic is easily oxidized to Propanoic under the action of air or other oxidizing agents. The oxidation process can use salts such as cobalt, manganese and copper as catalysts, and can also be carried out under normal pressure or slightly increased pressure without catalysts. The yield of this method can reach more than 95%, and more than 90% of the Propanoic output in the United States is produced by this method.
2. Oxidation of light hydrocarbons is one of the main methods for producing acetic acid. For every 100t of acetic acid produced, 25t of formic acid and 10t of propionic acid can be produced by-product.
3. The method of ethanol carboxylation is to use ethanol, carbon monoxide and water as raw materials, and carry out catalytic carboxylation under high temperature and high pressure to obtain propionic acid. DuPont Company of the United States has built a production device with an annual output of 5000 tons by this method. This method has harsh process conditions, high requirements for equipment materials, and limited development.
4. The direct oxidation method of low-carbon hydrocarbons can co-produce formic acid and propionic acid when low-carbon hydrocarbons are used as raw materials to oxidize acetic acid, and Propanoic can be obtained after separation.
5. Rapper (Reppe) method ethylene reacts with carbon monoxide and water under the catalysis of nickel carbonyl to synthesize Propanoic in one step. The reaction conditions are 250-320°C and 10-30MPa.
6. Hydrolysis of propionitrile is produced by hydrolysis of propionitrile under the catalysis of concentrated sulfuric acid.
7. Acrylic acid is produced by hydrogenation and reduction of acrylic acid.

Propanoic Production Process

Propanoic production methods include chemical synthesis and microbial fermentation. At present, propionic acid is mainly produced by chemical synthesis in industry. Propionaldehyde oxidation, Rapa method and light hydrocarbon oxidation are the most commonly used methods in propionic acid production industry. In addition, acrylonitrile method, ethanol carbonyl method, n-propanol oxidation method, propane (butane, paraffin) liquid phase oxidation method, etc. can also be used in the production of propionic acid, but due to the large investment in equipment and other reasons, it has not been used in practice so far. .

Propionaldehyde Oxidation Method At present, in industrial production, ethylene, carbon monoxide and hydrogen are used as raw materials, and propionic acid is prepared by hydroformylation of ethylene under the catalysis of cobalt carbonyl or rhodium carbonyl. Propionaldehyde oxidation process is mature, and it is currently the production method of propionic acid with the largest output. The main disadvantage of this method is that the process is complicated, the equipment is various, and the requirements for equipment and pipeline materials are relatively high.

The Repper method, also known as the ethylene oxo method, is a patent of the German BASF company. It uses ethylene as raw material to react with carbon monoxide and water under the catalysis of nickel carbonyl to generate propionic acid. The reaction is carried out under the conditions of 250-320°C and 10-30MPa. Carbonyl complexes of cobalt, iron, rhodium, iridium, platinum, palladium, ruthenium, molybdenum-nickel, tungsten-nickel, etc. can also be used as catalysts.

The Rapa method has the characteristics of low raw material cost, simple process flow, high conversion rate, good selectivity, and simple operation. However, due to the severe corrosion of propionic acid under high temperature and high pressure, it is necessary to use a reactor whose inner wall is lined with silver. In view of this, many foreign companies have made many improvements to this method. In 1975, the low-pressure synthesis of butyraldehyde from propylene was successfully developed, which greatly promoted the development of the technology of direct carbonylation of ethylene to propionic acid. This new process has the potential to be the best method for Propanoic production.

About Products:
If you need Propionic acid as a cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced Propionic acid manufacturer and supplier, ZSpharmac will provide Propionic acid raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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