Zhishang Chemical

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Zhishang Chemical

Pro-Xylane CAS 439685-79-7

Molecular Formula: C8H16O5

Formula Weight: 192.21

ZSpharmac: Pro-Xylane Supplier

Product Name: Pro-Xylane
CAS No: 439685-79-7
Purity: 99%

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Basic Info

Product Name:Pro-Xylane
Other Names:HydroxypropylTetrahydropyrantriol
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Yellowish Liquid
EINECS No.:456-880-5
Provide:Pro-Xylane MSDS;
Pro-Xylane COA

What is Pro-Xylane?

Puri-Xylane, generally called Pro-Xylane, is a xylose by-product with anti-aging energetic compounds, which can promote the synthesis of collagen, make the skin stronger as well as extra elastic, enhance fine lines on the neck, and avoid senescence. Pro-Xylane is a glycoprotein combination originated from xylose. Considering that xylose exists in huge quantities in beech trees, it has the capacity to advertise the production of glucosaminoglycans, particularly mucopolysaccharides (Tricks). As Boseine extracted from the beech tree, its activity is similar to that of xylose.

Pro-Xylane is additionally a non-ionic surfactant with great diffusion as well as emulsification homes. As a result, the reduced concentration of Boseine in the onset was additionally made use of as an emulsifier or dispersant for skin care items. But nevertheless, there is a skin obstacle, as well as the biological activity of Pro-Xylane itself is weak, so Bose requirements to reach a high focus on the skin surface to boost the absorption through osmosis with the help of a concentration slope. Nonetheless, high-concentration Pro-Xylane has a high thickness as well as is not extremely comfortable to make use of, so the percentage of Pro-Xylane included many products is low.

Pro-Xylane Property

Boiling point 376.0±42.0 °C(Predicted)
density 1.368±0.06 g/cm3(Predicted)
vapor pressure 0Pa at 25℃


What are the Main Functions of Pro-Xylane?

1. Turn on mucopolysaccharide (Tricks) synthesis:
This state-of-the-art component, based upon the principle of bionics, includes a sugar called xylose that turns on the synthesis of mucopolysaccharides (Tricks). There are a great deal of mucopolysaccharides in the extracellular matrix (ECM) of our skin, most of which are glycopolymers (GAG) made up of uronic acid and also aminoglucose, as well as these mucopolysaccharides play an extremely essential duty in the skin. Function, since mucopolysaccharides can absorb dampness and contribute in avoiding skin dampness loss.
At the same time, given that mucopolysaccharide takes in a big quantity of water, it can create a framework that can be imagined as a colloid made up of water. At the same time, the water absorption capability of the molecular structure of these healthy and balanced protein mucopolysaccharide Tricks makes the matrix network structure a lot more flexible, which helps to enhance the density of cells as well as improve the versatility of the skin. These are very important variables that affect the flexibility as well as structure of the skin.

2. Stimulate the manufacturing of glycosaminoglycans (GAGs) in the skin:
Hydroxypropyltetrahydropyranotriol is a glycoprotein blend that stimulates the production of glucans aminoglycosides (GAGs) in the skin. GAGs are the primary elements of the extracellular matrix, as well as the hyaluronic acid contained therein is one of the major elements of Tricks. Hyaluronic acid has a strong capacity to absorb water as well as shop water. When infused right into the dermis, it can achieve the impact of loading as well as supple skin, making the skin plump as well as elastic. Hyaluronic acid is also typically used to fill in clinically depressed locations of the skin, consisting of wrinkles.
In terms of skin structure, GAGS, the dermis of the skin mostly consists of collagen, elastin, as well as extracellular matrix (consisting of Tricks).

Precautions for Pro-Xylane Application

1. Pro-Xylane, as a derivative of the xylose family, is naturally essential for its ability to retain moisture when applied in formulations. When adding too much pure product Bose, it is necessary to pay attention to the impact on the skin feel of the formulation. If the added amount is too high (greater than 10%), it may be necessary to reduce the amount of other humectants in the formula to reduce the stickiness of the formula.

2. The influence of PH on the formulation system: basically no influence, the normal pH of Bose will be controlled at around 6-8 during production, the pH of the whole system can be comprehensively designed according to the formulation, for example, the system uses carbomer, and then uses Pro-Xylane, the final PH feels too high. At this time, when neutralizing carbomer, just add some alkali. Generally speaking, when using Pro-Xylane, it can be regarded as an ordinary neutral raw material, and there is no need to think too much about it. System pH influence.

3. The stability of Pro-Xylane: Generally speaking, Pro-Xylane has good stability similar to that of general sugars. It shows excellent stability under high temperature and light, and there is almost no discoloration.

Synthesis of Pro-Xylane

The original synthesis route of Pro-Xylane is: using a large amount of xylose extracted from beech as the main raw material, and undergoing Knoevenagel condensation reaction with acetylacetone (Acetylacetone) in alkaline aqueous solution (that is, a compound with active methylene (such as malonate, β-ketoester, cyanoacetate, nitroacetate, etc.) under the catalysis of ammonia, amine or its carboxylate, undergoes aldol condensation with aldehydes and ketones, dehydration And get α, the reaction of β-unsaturated compound), generate 1-C-(beta-D-xylopyranosyl)-acetone. After that, a reduction reaction occurs with sodium borohydride to reduce the ketone carbonyl group in the product to obtain 1-C-(beta-D-xylopyranosyl)-2-hydroxyl-propane, namely Pro-Xylane ( Pro-xylane).

Functional Role of Pro-Xylane

1. Stimulates the production and construction of GAGs (cumulan extracellular matrix) (e.g. gel-like protein self-plasma network and sugars as scaffolds and intercellular shock absorbers) to make the matrix gel-like, increasing the firmness of cells and skin .
2. Functions as a channel to lead the passage of repair service molecules, such as some healthy proteins that permit cells to grow.
3. Utilizing the task of the extracellular matrix to send messages to young cells while re-stimulating aging cells.
4. Strengthen the basement membrane function, reduce allergies and inflammation. The skin improvement effect of Pro-Xylane is comprehensive, not limited to the extracellular matrix, but also the connection between the matrix and cells, the density and firmness of the skin, and the promotion of the self-production of type VI and type IV collagen. Together with niacinamide and tranexamic acid, Pro-Xylane is listed as the three favorite multi-effect skin beautifying ingredients of Teacher Cai.

About Products:
If you need Pro-Xylane, a cosmetic raw material, please contact our service staff directly, and we will provide you with high-quality products at the best price.
As an experienced Pro-Xylane manufacturer and supplier, ZSpharmac will provide Pro-Xylane raw materials for customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Pro-Xylane Quotation