Polyvinylpyrrolidone Cross-Linked can be synthesized from NVP or PVP. NVP is a fine chemical product with high added value. It is easily soluble in water and many other organic solvents. It has active chemical properties and is widely used. As a traditional production method, the acetylene method has large investment, high energy consumption, and the risk of explosion. However, the direct method of aminolysis of r-butyrolactone to prepare NVP has the advantages of high product purity, less by-products, and good safety. It is the future development trend.
PVP is a series of polymer fine chemical products with excellent performance obtained from NVP monomer through homopolymerization, copolymerization, cross-linking polymerization and other methods. Generally, PVP can be divided into three types: pharmaceutical grade (food grade), cosmetic grade and industrial grade. It has excellent solubility, physiological compatibility, complexation, film-forming, adhesive ability, water absorption and moisture retention, and is widely used in the fields of biomedicine, daily chemical industry, pigment coating, textile and papermaking, oil production, photosensitive materials and electronics industry. have a broad and important role. The acetylene method is one of the mature methods for industrial production of PVP. At present, the r-butyrolactone method, which has been studied more, has mild operating conditions, but is expensive and expensive.
Food industry: Polyvinylpyrrolidone Cross-Linked is the only method to solve polyphenol-protein precipitation from the perspective of polyphenols. The effect is very good, and the effect will be better if it is used in conjunction with other stabilizers such as silica gel. PVPP was superior to PVP in its ability to remove certain polyphenolic compounds from plants. The polyphenolic compounds adsorbed by PVPP can be determined by extraction and separation, so that the amount of PVPP added can be controlled in production. The cost of using disposable PVPP in beer production is high, and it will reduce the antioxidant capacity of wine. The use of recycled PVPP requires equipment such as addition, filtration, and recovery. Recycling PVPP can effectively reduce production costs.
At present, PVPP has been allowed to be used as a stabilizer in the food industry in China. At present, the domestic PVPP production technology is still relatively backward, the management level of the enterprise needs to be improved, the inspection method needs to be improved, and the quality cannot be fully guaranteed. With the development of social economy and the increase of PVPP demand, my country’s PVPP market will be further standardized, and product competitiveness will be further improved.
Due to the clarification of PVPP that can be used in beer, red wine, liquor, fruit juice, etc., the development of these industries directly affects the Polyvinylpyrrolidone Cross-Linked market. China’s beer market is gradually penetrating from first- and second-tier cities to third-tier cities and township markets. Compared with other countries, China’s per capita beer consumption is still low, and the market has huge growth potential. It is estimated that the growth rate of the high-end beer market will be over 20% in the next 5 years; red wine is the second most popular beverage after beer in the international alcohol market, but the per capita consumption of red wine in my country is far lower than the per capita consumption of the world , it is expected that my country’s red wine will grow rapidly;
my country’s liquor industry has changed from a period of rapid expansion to a period of relative stability this year, but its output, output value, taxation, sales revenue, number of enterprises, and investment in infrastructure continue to grow; Juice is the main reason to attract consumers. The per capita consumption of fruit juice drinks in my country is still low, and there is still a huge room for development. With the development of the brewing industry, PVPP will have a broad application space.
Pharmaceutical industry: PVPP is an excellent disintegrant. The research and application of pharmaceutical excipients in my country started relatively late, and the products in the pharmaceutical excipients market lacked innovation, and the impetus to promote its rapid development was insufficient. The rapid development of pharmaceutical excipients is a considerable requirement for the overall upgrading of the pharmaceutical industry.
The substantial improvement of drug quality and safety level and the complexity of modern dosage forms inevitably require the development trend of pharmaceutical excipients to be more refined, and some products and technologies (such as compound excipients) need to be developed to solve possible problems in the production process of preparations . In addition, specialized, improved and functional pharmaceutical excipients will soon be developed. As a new type of pharmaceutical excipient, PVPP occupies an important position in the field of pharmacy, and plays a powerful role in promoting the development of new drugs, new dosage forms, and new varieties. It is expected to be used in excellent sustained and controlled release materials, non-toxic and efficient transdermal enhancers, targeted preparation materials, non-toxic and efficient drug carriers, and composite materials suitable for various drug preparations.
In short, with the development of the economy and the improvement of the level of science and technology, many new fields will be gradually developed and explored, and the demand for Polyvinylpyrrolidone Cross-Linked will continue to grow, which will definitely create huge social benefits and economic value.