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Polyglycol CAS 25322-68-3

Molecular Formula: N/A

Formula Weight: 0

ZSpharmac: Polyglycol Supplier

Product Name: Polyglycol
CAS No: 25322-68-3
Purity: 99%

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Basic Info

Product Name:Polyglycol
Other Names:Polyethylene Glycol
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White to Very Pale Yellow Waxy Solid
EINECS No.:500-038-2
Provide:Polyglycol MSDS;
Polyglycol COA

What is Polyglycol?

The number after industrial polyethylene glycol recommends the regular molecular weight. As an instance, polyethylene glycol-400 recommends that the commercially comfortably used polyethylene glycol has a typical molecular weight of concerning 400.
Anemic viscous liquid or white solid. Reduced poisoning! Soluble in water along with a variety of natural solvents, rapidly soluble in fragrant hydrocarbons, rather soluble in aliphatic hydrocarbons. It is not hydrolyzed for a long period of time, steady to warm, along with does not react with a number of chemical reagents. Specific metal salts are soluble in polyethylene glycol at fretting 100 ° C in addition to keep stable at area temperature level. These steel salts include calcium, cobalt, copper, iron, magnesium, manganese, tin along with zinc chlorides, potassium iodide as well as ethylmercury, among others. It can be made use of as a plasticizer, conditioner, moistening representative, lubricating material, solvent, glue, along with can likewise be utilized to prepare flavors as well as additionally pharmaceutical prep work.

Polyglycol Property

Melting point 64-66 °C
Boiling point >250°C
density 1.27 g/mL at 25 °C
vapor density >1 (vs air)
vapor pressure <0.01 mm Hg ( 20 °C)
refractive index n20/D 1.469
Fp 270 °C
storage temp. 2-8°C
solubility H2O: 50 mg/mL, clear, colorless
form waxy solid
color White to very pale yellow
Specific Gravity1.128
PH5.5-7.0 (25℃, 50mg/mL in H2O)
Water Solubility Soluble in water.


Polyglycol Uses

Polyglycol as well as polyethylene glycol fat esters are typically made use of in cosmetic industry along with pharmaceutical market. As a result of the fact that Polyglycol has lots of outstanding household or business homes: water-soluble, non-volatile, physiologically inert, light, lubricating, and likewise makes the skin moist, soft, as well as likewise positive after use. Polyethylene glycol with different loved one molecular mass parts can be picked to change the density, hygroscopicity and likewise organization framework of the item. Polyethylene glycol (Mr<2000) with a low molecular weight is suitable for use as a wetting agent and a consistency regulator, used in creams, lotions, toothpaste and shaving cream, etc., and also suitable for non-cleaning hair care products, Gives hair a silky shine. Polyethylene glycol with high molecular weight (Mr>< 2000) with a reduced molecular weight appropriates for usage as a wetting representative and an uniformity regulatory authority, used in lotions, lotions, toothpaste and also shaving cream, etc, as well as also suitable for non-cleaning hair treatment items, Offers hair a smooth shine. Polyethylene glycol with high molecular weight( Mr > < 2000 )with a decreased molecular weight appropriates for usage as a moistening representative and also an uniformity regulatory authority, used in lotions, lotions, toothpaste as well as cutting lotion, and so on, and additionally suitable for non-cleaning hair treatment things, Provides hair a smooth luster. Polyethylene glycol with high molecular weight(Mr > 2000)appropriates for lipsticks, antiperspirant sticks, soaps, cutting soaps, structures along with appeal cosmetics. In tidying up reps, polyethylene glycol is likewise taken advantage of as a postponing and also thickening agent. In the pharmaceutical industry, it is made use of as a base for creams, creams, lotions, creams as well as suppositories. Easily used polyethylene glycol (such as Polyethylene Glycol NF, Dowchemical Co.) which is suitable for food as well as likewise pharmaceutical usage is more suitable for cosmetic use. The application of methoxypolyethylene glycol as well as likewise polypropylene glycol resembles that of polyethylene glycol. Polyglycol is extensively utilized in numerous pharmaceutical formulas such as shots, topical formulations, ophthalmic solutions, oral in addition to rectal formulations. Strong top quality polyethylene glycol can be included in fluid polyethylene glycol to readjust thickness for topical lotion; polyethylene glycol mix can be made use of as suppository base; liquid alternative of polyethylene glycol can be made use of as putting on hold representative or utilized to readjust numerous other The density of the suspension tool; the combination of polyethylene glycol as well as also various other emulsifiers improves the security of the solution. Furthermore, polyethylene glycol is also made use of as a movie ending up representative, tablet computer system lube, regulated release product, etc.

Polyglycol Application in Biomedical Field

Clinical Polyglycol is similarly called polyethylene oxide (PEO). Straight polyether gotten by ring-opening polymerization of ethylene oxide. The substantial uses in the biomedical location are as adhere to:
1) Fluid for phone call lenses. The density of Polyglycol liquid option is sensitive to shear expense in addition to microorganisms are challenging to expand on polyethylene glycol.
2) Produced lubricating substances. Condensation polymer of ethylene oxide with water. It can be made use of as an ointment matrix for preparing water-soluble medicines, and likewise can additionally be made use of as a solvent for medications that are tough to liquify in water such as acetylsalicylic acid as well as high degrees of high levels of caffeine, and also likewise can be used for the preparation work of injections.
3) Providers for continuous medication launch along with incapacitated enzymes. Covering the Polyglycol liquid solution on the external layer of the pill can regulate the diffusion of the medication in the pill to improve the performance of the medicine.
4) Surface alteration of clinical polymer products. The biocompatibility of the clinical polymer product touching blood can be improved by using the amphiphilic copolymer including polyethylene glycol to adsorb, trap as well as likewise graft on the surface of the specialist polymer product.
5) Making alkanol birth control film.
6) Making hydrophilic anticoagulant polyurethane.
7) Polyethylene glycol 4000 is an osmotic laxative, which can enhance the osmotic stress in the digestive system tooth cavities, absorb water, soften the feces, raise the quantity, as well as additionally advertise digestion system peristalsis as well as defecation.
8) Denture fixatives. Making use of polyethylene glycol’s non-toxic as well as gel-forming residential or commercial properties, it is made use of as a part of denture fixatives.
9) PEG4000 as well as PEG6000 are frequently used to promote cell combination or protoplast combination along with aid organisms (such as yeast) occupy DNA throughout makeover. PEG can absorb water in solution, so it is also made use of to concentrate the remedy.

Polyglycol Identification Test

Solubility Polyglycol with an obvious molecular weight of 1000 (or over) is rapidly soluble in water. Polyethylene glycol is soluble in numerous all-natural solvents, consisting of aliphatic ketones and aldehydes, chloroform, glycol ethers, esters, and also fragrant hydrocarbons; it is insoluble in ether along with the majority of aliphatic hydrocarbons. Solubility in water and likewise all-natural solvents decreases with improving molecular weight.
Apparent molecular weight If the noticeable molecular weight is less than 1000, it is 95.0% to 105.0% of the proclaimed well worth; if the apparent molecular weight is in between 1000 as well as 7000, it is 90.0% to 110.0% of the announced value; if it is more than 7000, it is 87.5% of the proclaimed value %~ 112.5%.
The approach of figuring out the obvious molecular weight is as follow.
Prep job of phthalic anhydride alternative Take 49g of phthalic anhydride, placed it right into a brown container, as well as likewise consist of 300ml of newly distilled pyridine. Shake extremely to liquify and also leave over night before usage. Prep job of fluid polyethylene glycol instance service Diligently take 25ml of the above-mentioned phthalic anhydride remedy as well as put it into a tidy, dry, heat-insulated anxiety container. Properly assess a specific amount of sample and also put it into the bottle, the amount amounts the ratio of its expected visible molecular weight split by 160 (if the noticeable molecular weight of the sample is 200, take 1.3 g of the instance, if the noticeable molecular weight is 600, then take 3.8 g). Stopper it, cover it safely as well as put it in a textile bag.
Prep Work of Strong Polyglycol Sample Treatment Diligently take 25ml of those phthalic acid service and also placed it right into a clean, dry, heat-insulated stress and anxiety container. Appropriately think about a particular amount of sample and placed it right into the bottle after pre-melting. The quantity amounts the proportion of the approximated apparent molecular weight divided by 160; nonetheless because of its solubility, no example has to exceed 25g. Add 25 mL of pyridine recently distilled from phthalic anhydride, shiver to liquify, stopper, cover well and also position it in a towel bag.
Treatment Immerse the example container in a water washroom at 96-100 ° C, the immersion deepness synchronizes as the fluid degree of the product in the bottle. After home heating in a water washroom for 30-60 minutes (60 mins for those with an evident molecular weight ≥ 3000), take it out and amazing to location temperature level. Meticulously open the lid to remove the staying stress in the bottle, then take it out from the cloth bag, include 5 decreases of 1% phenolphthalein in pyridine, and also titrate with 0.5 mol/L salt hydroxide service till pink shows up, along with preserve it for 15s. At the same time, put 25ml of phthalic acid solution into the instance container, in addition to perform a vacant examination as above. Then obtain the obvious molecular weight of the instance according to the adhering to formula: the kinematic viscosity of Polyglycol with numerous noticeable molecular weights at 100 ° C( ± 0.3 ° C )is as follow: Gauging tool tackles Ubbelohdes postponed degree’ viscosimeter (Ubbelohdesuspendedlevel’ viscosimeter), see Number 11102. Round B has a regular amount of 5ml. The top in addition to lower restrictions of the B round are the highest possible along with many cost effective common lines of the fluid. The material taken advantage of to establish the viscosity of (300 ~ 600) × 10-6m2/ s embraces No. 3 viscometer, and its capillary dimension is (2.00 ± 0.04) mm. Prior to the measurement, the tool should certainly be given a constant temperature level in a constant temperature level bathroom, and then the moment needed for the fluid to decrease from the T1 line to the T2 line should be established. In order to get precise outcomes, it has to be between 80 and also 100 s (accurate to 0.1 s). The thickness is determined according to the formula:
c= v/t1.
In the formula, c– thickness consistent gauged by a viscometer with a particular oil of identified viscosity;.
v– Kinematic density of the figured out liquid, 1 × 10-6m2/ s;.
t1 – needed flow time, s.

About Products:
If you need Polyglycol as a cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced Polyglycol manufacturer and supplier, ZSpharmac will provide Polyglycol raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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