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Polyethylenimine CAS 25987-06-8

Molecular Formula: C4H13N3

Formula Weight: 103.17

ZSpharmac: Polyethylenimine Supplement

Product Name: Polyethylenimine
CAS No: 25987-06-8
Purity: 99%

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Basic Info

Product Name:Polyethylenimine
Other Names:Polyethylenimine, Ethylenediamine Branched
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Colorless Transparent Liquid
Provide:Polyethylenimine MSDS;
Polyethylenimine COA

What is Polyethylenimine?

Polyethyleneimine is a common water-soluble polyamine. Due to the plentiful nitrogen atoms in the macromolecular chain, polyethyleneimine has solid protonic properties, so it has a large range of applications, such as in the field of papermaking and also pulping. Flocculant, metal ion adsorption in water treatment area, cationic polymer non-viral gene carrier in clinical area, and so on.Ring-opening polymerization of aziridine is a synthetic method that can prepare polyethyleneimine. In the field of polymer synthesis, compared with the polymerization of propylene oxide with three-membered rings, the research progress of ring-opening polymerization of aziridine is relatively slow. Although Bergman and Toste et al. first reported the synthesis of narrowly distributed polyethyleneimine-based polymers by the living ring-opening polymerization of N-sulfonyl-C-alkyl substituted aziridines in 2005, the polymerization since then The response was ignored for nearly a decade. Until recent years, a variety of different catalytic initiation systems for the living anionic ring-opening polymerization of N-sulfonyl-substituted aziridines have been developed, but the initiators are often limited to terminally nonfunctionalized N-benzyl-sulfonic acid Amide is not conducive to the functionalization of the polymer chain end or further modification (post-modification) to synthesize polyethyleneimine-based polymer materials of block or complex topology. Therefore, it is of great significance to develop novel initiators to precisely control the end groups of polyamine chains.

Polyethylenimine Property

density 1.08 g/mL at 25 °C
vapor pressure 9 mm Hg ( 20 °C)
refractive index n20/D 1.5240


Polyethylenimine Uses

The level of polymerization of polyethyleneimine used in the paper sector is around 100. Polyethyleneimine has high reactivity, can respond with hydroxyl teams in cellulose and also cross-link polymerization, to ensure that the paper has wet stamina. The existence of any acid, alkali and also light weight aluminum sulfate will affect its damp toughness and also retention. Utilized as a damp stamina representative for unsized breathable paper, a retention help as well as a beating representative in the papermaking process, it can reduce the whipping level of the pulp, improve the dewatering capability of the paper, accelerate the pulp water drainage, and also make the penalty fibers in the white water very easy to flocculate.
PEI and also its by-products are used for elimination of flocculants, heavy metal adsorbents and also surfactants in water treatment as well as gas filtration;
In the paper industry, it is used as a supporting synergist as well as a water drainage accelerator;
In the fiber sector, it is utilized as a damp toughness representative, antistatic therapy, flame resistant processing, contraction resistance, coloring enhancement, etc;.
Used in finishings, inks, and adhesives (including thermal welding and also plastic securing), it can advertise bond, creep resistance, boost pigment as well as filler diffusion, stop aggregation, as well as boost covering security, etc;.
Utilized in cosmetics to boost hair quality, anti-bacterial and soft skin;.
In oil extraction and deep well procedures, it can stop fluid loss, minimize viscosity, protect against paraffin deposition, as well as enhance clay security;.
It can be used in the medical and pharmaceutical fields to boost the compatibility of synthetic organs as well as blood, and also it can additionally be utilized as a finish for medical tools;.
Furthermore, it is additionally a component of ion exchange resin as well as exchange membrane, material crosslinking agent, formation help, electroplating gloss representative, steel rust prevention, gasoline and also gasoline accelerant, lubing oil additive, glass cleaner, liquid chromatography stationary phase, Polymer stimulants, and so on, are likewise used in the study of synthase models.

Polyethyleneimine Product Characteristics

Polyethyleneimine is a water-soluble polymer generated by the polymerization of ethyleneimine. It is not a totally linear polymer, yet a partly branched polymer having main, second and also tertiary amines. Polyethyleneimine, like various other reduced molecular weight amines, has different chemical sensitivities and can go through different chemical adjustments. Features ● Greatest cation thickness in existing materials. ● Really high activity. ● water solubility.
1. High attachment in addition to adsorption
Amino groups can react with carboxyl teams to develop hydrogen bonds.
Amino teams can respond with carboxyl teams to create ionic bonds.
Amino groups can respond with carbonyl teams to create covalent bonds.
Polyethyleneimine can integrate with various compounds because of its polar group (amino group) as well as hydrophobic team (vinyl team) structure. Utilizing these considerable binding pressures, it can be commonly taken advantage of in the fields of adhesives, inks, finishes, adhesives, etc
2. High cationicity
Polyethyleneimine exists as a polymeric cation in water, which can reduce the impacts of and also adsorb all anionic ranges, as well as can similarly chelate heavy metal ions. Using its high cationic residential properties, it can be made use of in the fields of papermaking water therapy, electroplating alternative, as well as dispersant.
3. Reactivity
Polyethyleneimine responds easily with epoxy, acids, isocyanate compounds and also acid gases because of its highly receptive secret and additionally secondary amines. Benefiting from this residence, it can be made use of as epoxy material catalyst, aldehyde adsorbent as well as shade fixer.

Polyethyleneimine Derivatives as Low-Toxicity and High-Efficiency Gene Carriers

Polyethyleneimine (PEI) is a class of cationic polymers shown to be efficient for gene distribution. However, PEI is not degradable, as well as the molecular weight of PEI influences cytotoxicity and also genetics transfer activity. To prepare eco-friendly genetics vectors with high transfection performance and also reduced cytotoxicity, we conjugated low molecular weight (LMW) PEI with a biodegradable backbone polyglutamic acid derivative (PEG-b-PBLG) by means of aminolysis, developing Polyethyleneimine conjugated with PEG-b-PLG-. g-PEI (GGI). 2 copolymers, GGI 30 as well as GGI 40, were synthesized. The chemical homes of GGI were defined utilizing IR, 1 H NMR and 13 C NMR, GPC and also CD, respectively. The deterioration habits of copolymer GGI in papain remedy was examined. GGIs display excellent DNA coagulation capacity and high security of DNA from nuclease destruction. The zeta possibility of the GGI/pDNA complicated has to do with 15 mV, the fragment size remains in the variety of 102-138 nm, and the N/P proportion is between 10 as well as 30. The particle dimension as well as morphology of the compounds were additionally validated by transmission electron microscopy (TEM). In cytotoxicity tests, GGI was significantly much less hazardous than Polyethyleneimine 25k. Also at high copolymer focus, GGI degradation products had negligible results on cells. The results of GFP flow cytometry and also fluorescence imaging showed that the transfection performance of GGIs in Hela, HepG2, Bel 7402 and 293 cell lines was substantially greater than that of PEI 25k. Significantly, b-PLG-g-Polyethyleneimine copolymers may be appealing cationic polymers for non-viral gene therapy.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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