Zhishang Chemical

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Zhishang Chemical

Phytosphingosine CAS 554-62-1

Molecular Formula: C18H39NO3

Formula Weight: 317.51

ZSpharmac: Phytosphingosine Supplier

Product Name: Phytosphingosine
CAS No: 554-62-1
Purity: 99%

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Basic Info

Product Name:Phytosphingosine
Other Names:Salicyl Phytosphingosine
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White White to Off-White Solid
EINECS No.:205-516-1
Provide:Phytosphingosine MSDS;
Phytosphingosine COA

What is Phytosphingosine?

Phytosphingosine is a phospholipid, a sort of fat typically situated in the outer layer of the skin. “It becomes part of the skin obstacle together with ceramides, cholesterol and also fats,” describes Nussbaum. The skin barrier is vital to making sure your skin looks terrific – think of it as your utmost security versus all the dirt, air pollution, substance and also other poisonous compounds your skin is continually pestered with. When the barrier is endangered or harmed, each of these unwanted variables can enter, creating whatever from inflammation to breakouts.

Phytosphingosine Property

Melting point 102 °C
Boiling point 483.7±40.0 °C(Predicted)
density 0.983
vapor pressure 0.2Pa at 20℃
refractive index 9 ° (C=1, Pyridine)
storage temp. −20°C
solubility Soluble in Ethanol (up to 2 mg/ml).
form White to off-white solid.
color White
Water Solubility 2.6mg/L at 20℃


Skin Benefits of Phytosphingosine

  1. skin’s natural barrier
    Phytosphingosine is a lipid that comprises the lipid obstacle of the skin, as well as it likewise consists of about 50% ceramides, 25% cholesterol, as well as concerning 10% to 15% fatty acids. Without these necessary lipids, the obstacle is deteriorated. A weak or damaged barrier allows dangerous substances such as allergens, germs and also irritants to pass through deeper into the skin, leading to dryness, itching as well as irritation. Interruption of the skin obstacle has been connected to skin problem such as acne, eczema, sensitive skin and also indications of aging. Skin treatment items having phytosphingosine can assist avoid these troubles.
  2. water loss
    Along with supplying protection from environmental variables, the skin’s lipid obstacle additionally acts to prevent extreme dampness loss. Transepidermal water loss, or TEWL, happens when the skin loses water to the surrounding environment and the air. This usually occurs when the skin ages as well as comes to be completely dry, or if the skin obstacle is interfered with by skin problem, bothersome products or ecological variables. Phytosphingosine and other lipids that compose the skin obstacle assistance secure dampness as well as stop skin dehydration.
    A 2017 research released in Archives of Dermatological Study found that phytosphingosine provides skin moisturization by modulating the filaggrin metabolic pathway straight responsible for the manufacturing of natural moisturizing variables. Natural moisturizing aspect, a term that defines a team of substances, such as amino acids, sugars, electrolytes, and so on, that maintain the skin obstacle undamaged, supple, and moisturized. Topical application of phytosphingosine helps renew the skin’s NMF.
  3. Anti-Aging
    Recovering your skin’s NMF is important as it is depleted with age and also everyday exposure to delicate active ingredients like drying cleansers and also denatured alcohol. This causes noticeably dry, limited, half-cracked skin. Consequently, noticeable signs old such as great lines, wrinkles as well as dry skin can be lowered by using components that aid replenish NMF. The result is skin that looks smoother, moisturized and also stronger.

Effects of Phytosphingosine on Animals

Just like humans, the lipid barrier of dog skin can be jeopardized. This can trigger dry, itchy and inflamed skin. Phytosphingosine is a wonderful component for pet dogs as it helps reconstruct the lipid obstacle and keep skin healthy! It is additionally an anti-inflammatory representative, so it can assist calm inflamed skin.

Phytosphingosine is especially beneficial for wrinkled dogs, such as bulldogs and pugs. Dust, particles and dampness conveniently caught in skin folds as well as wrinkles can result in completely dry, broken and also infected skin otherwise cared for properly. Phytosphingosine for dogs sustains the skin’s barrier function as well as helps prevent the formation of skin irritability or infection.

Phytosphingosine Side Effects

Researches have actually discovered that phytosphingosine is an inert and safe ingredient. Very few people complain about the negative effects of phytosphingosine on the skin. However, it may irritate sensitive parts of your body such as the eyes, nose, within the mouth, etc.

The EWG (Ecological Working Team) conducted a study on phytosphingosine and also rated it a 1 out of 10 danger element. It plainly specifies the lowest degree of adverse effects. In fact, phytosphingosine is an all-natural hero for the skin.

That being stated, it’s best to take preventative measures prior to using any brand-new item. Do a patch test on a small location 24 hr before real application. You will certainly recognize if you have any kind of allergy to it. Consult your dermatologist if you experience any kind of major negative effects after utilizing this product.

While words “phytosphingosine” seems difficult, its active ingredients are simple and it profits your skin in multiple methods. It hydrates as well as secures your skin from environmental assailants, making it an advantage for acne-prone as well as delicate skin.

About Products:
If you need Phytosphingosine, a cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced Phytosphingosine manufacturer and supplier, ZSpharmac will provide Phytosphingosine raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, and customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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