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Perilla Ocymoides Leaf Extract

Molecular Formula: N/A

Formula Weight: 0

ZSpharmac: Perilla Ocymoides Leaf Extract

Product Name: Perilla Ocymoides Leaf Extract
CAS No: 0
Purity: 99%

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Basic Info

Product Name:Perilla Ocymoides Leaf Extract
Other Names:Perilla Leaf Extract
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Slightly Yellow Viscous Liquid
Provide:Perilla Ocymoides Leaf Extract MSDS;
Perilla Ocymoides Leaf Extract COA

What is Perilla Ocymoides Leaf Extract?

Perilla Ocymoides Leaf Remove is the dry fallen leave essence of Perilla frutescens (L.) Britt, the Lamiaceae plant. The major active component is perilla oil, which has various health care functions and also has been widely utilized in medication, food, fragrance in addition to Chemicals and other markets.

Perilla Ocymoides Leaf Remove Source Plant

It is the dried leaves of Perilla frutescens (L.) Britt of the Lamiaceae plant. Perilla is one species and three varieties in the world, produced in eastern Asia; all produced in China, and can be used medicinally. Also known as Su Ye, Chi Su Ye, Fragrant Su Ye.
【Plant form】annual herb. Stems 0.3-2m high, green or purple, obtuse quadrangular, with 4 grooves, densely villous. The leaves are broadly ovate or round, 7-13cm long, 4.5-10cm wide, pointed at the apex, round or broadly cuneate at the base, with coarsely serrated margins above the base, green or purple on both sides, or only purple below, and sparsely soft above. Hair, below is adnate pubescent; petiole 3-5cm long, flat dorsal and ventral, densely villous. Circular umbels with two flowers, composed of 1.5-15cm long, densely pubescent, terminal and axillary racemes biased to one side; bracts broadly oval or nearly round, about 4mm long and wide, with short apex at the apex , The outer cover is reddish-brown glandular point, the margin is membranous; the pedicel is 1.5mm long, densely pubescent. The calyx is bell-shaped, 10-veined, straight, the lower part is villous, mixed with yellow glandular points, and the inner throat has a sparsely pubescent ring; the corolla is white to purple, 3-4mm long, 3-4mm wide, and the crown tube is short, 2-2.5mm long, oblique bell-shaped throat, nearly 2-lip-shaped crown and eaves, slightly absent upper lip, 3-lobed lower lip, larger middle lobe, and lateral lobes similar to the upper lip. Stamens 4, anterior pair longer, inserted into throat, anthers 2-celled, cells parallel, slightly forked or extremely forked afterwards; style apex equal to 2 lobes; front of disc is digit-shaped enlargement. Nutlets are spherical, gray-brown, 1.5mm in diameter, reticulated, flowering from August to November, and fruit from August to December.


Pharmacological Effects of Perilla Ocymoides Leaf Extract

1. Sedative and analgesic effects
Perilla Ocymoides Leaf Extract in Perilla Ocymoides Leaf Extract has sedative and analgesic activity synergistically with stigmasterol. Dill celery brain isolated from Perilla can prolong cyclohexenebarbital-induced sleep time in a dose-dependent manner within a certain range. At a dose of less than 10 mg/kg, the activity of dill celery brain is almost equivalent to that of chlorpromazine hydrochloride; while at a high dose, it can cause hallucinations; when the dose reaches 718 mg/kg, continuous convulsions can be seen in sleeping mice.
2. Anti-tumor effect
Perilla Ocymoides Leaf Extract Perilla alcohol can inhibit the activity of virus-induced carcinogenesis, can significantly inhibit the incidence of breast cancer caused by chemical carcinogens or subcutaneously transplanted tumor strains, reduce the weight and volume of tumors, prolong the time of tumor appearance, and can inhibit breast cancer. Cancer growth and rat liver tumor cell growth.
3. Antipyretic effect
Perilla leaf decoction orally and intravenously infusion have a slight antipyretic effect on experimental fever rabbits caused by mixed typhoid vaccine. This may be related to the stimulation of sweat gland secretion.
4. Effect on blood sugar
Perilla Ocymoides Leaf Extract perilla oil (mainly containing perilla aldehyde) orally administered to rabbits after 12 hours of fasting can dilate skin blood vessels and increase blood sugar. After perilla aldehyde is used to make oxime (Oxim), oral administration is better than perilla oil.
5. Antibacterial and antiviral effects
Perilla Ocymoides Leaf Extract Perilla aldehyde and citral also have bacteriostatic effect on pathogenic dermatophytes. The volatile oil of perilla leaf extract has strong antibacterial effect on Staphylococcus aureus among Gram-positive bacteria and Escherichia coli among Gram-negative bacteria, especially Staphylococcus aureus. Perilla Ocymoides Leaf Extract has inhibitory effect on common bacteria. In addition, perillaldehyde, pinene and limonene have anti-Pseudomonas aeruginosa activity.
6. Anti-allergic effect
The anti-allergic substances of perilla leaves are water-soluble, heat-resistant, non-volatile aroma components, and have the ability to directly inhibit the production of TNF by macrophages in vitro. Perilla Ocymoides Leaf Extract can also inhibit the production of IgE, inhibit the production of DNP-IgE antibody and total IgE antibody, but has no effect on DNP-IgG antibody.
7. Anti-inflammatory effect
Intraperitoneal injection of perilla leaf juice to mice can make peritoneal exudate neutrophils accumulate, and neutrophils account for (89±6)% of exudate cells 6 hours after injection. Furthermore, the effect of perilla leaf juice on tumor necrosis factor (TNF) was observed, and it was found that perilla leaf juice could reduce the elevated TNF level in blood by 50% to 75%. TNF is mainly a cytokine secreted by macrophages and plays an important role in antibody inflammatory response and immune defense. However, when TNF is excessive, it will cause tissue damage, pathological changes and symptoms, such as fever, anemia, hemorrhage and necrosis, and even shock. Therefore, when the excess TNF is inhibited, the above pathological changes and symptoms may be weakened or eliminated.
8. Effects on the respiratory system
Kechuanbiwenan, which is mainly based on Perilla Ocymoides Leaf Extract, has a good antitussive and asthmatic effect by inhaling the drug gas. The volatile oil of perilla leaves has antitussive effect, and the antitussive strength is about 1/5 of that of codeine.
9. Hemostatic effect
The blood coagulation time, thromboplastin time, prothrombin time and euglobulin dissolution time were tested by intravenous injection of perilla leaf preparation into rabbits. The results showed that perilla has a promoting effect on the intrinsic coagulation system, but the effect on the extrinsic coagulation system was not obvious.
10. Other functions
Perilla aldehyde contained in perilla oil is a unique aroma component of perilla leaves. Perilla leaves can enhance the phagocytic function of macrophages, induce interferon in the body, and have immune function. Perilla leaves can reduce bronchial mucus secretion and relieve bronchospasm. For Ehrlich ascites cancer mice, perilla leaves can inhibit the proliferation of cancer cells. Perilla leaves also have a strong antiseptic effect.

Perilla Ocymoides Leaf Extract Application

Perilla Ocymoides Leaf Extract is widely used in the food industry, such as food flavoring, antiseptic, antibacterial, color enhancement, etc. The pigments, aroma components and nutrients in perilla essential oil can be used for the development and processing of various foods such as candied fruit, candy, leaf powder, vegetable oil, cakes, nutritional beverages, etc., or direct processing of edible perilla leaves, such as pickling , platter, fried food, mixed use, whole powder, etc. In addition, the rosmarinic acid contained in essential oils has strong antioxidant properties and good thermal stability. Currently, in Japan and Korea, perilla essential oil is used as a spice in soups, stews, and roasts. As a new type of food additive, it will contribute to the research and development of new products, continuously improve the color, flavor, nutrition and other edible quality of food, optimize the dietary structure of residents, and promote the development of the food industry to a certain extent.
Perilla Ocymoides Leaf Extract can be used in medicine and health food, and it has great potential in the research and development of disease prevention and health food. Perilla leaf essential oil has good health care effects and has been clinically used for the treatment of allergy, stroke, myocardial infarction, cerebral infarction, hyperlipidemia, hypercholesterolemia, platelet aggregation, and tumor cancer. As a biologically active ingredient, it is added to medicines, which improves the quality of medicines to a certain extent and significantly improves the therapeutic effect, such as antitumor drugs, perilla leaf extract, perilla tocopherol syrup and other products. In addition, it also has health effects such as anti-aging, protecting eyesight, enhancing intelligence and memory, improving sleep, etc. It is a public safety food raw material that has been approved by the US FDA. It is worth mentioning that rosmarinic acid in essential oils is a phenolic acid compound with anticoagulant, antibacterial, anti-inflammatory, antiviral and other activities, and is a multifunctional pharmaceutical intermediate. As a biologically active ingredient, it has many functions and wide uses, providing new raw materials and new ideas for the medical field.
Perilla Ocymoides Leaf Extract will be a bright spot in the development of the industry. As a multi-functional, non-polluting, high-quality industrial raw material, it is not only used in household daily chemical products, such as cosmetics, perfumes, aromatherapy, and some high-end luxury care products, but also in heavy industrial production, such as the manufacture of varnishes, paints, dyes, machinery The economic benefits of oil use, light industrial textiles, leather appliances, etc. are outstanding and have huge development potential.

Identification of Perilla Ocymoides Leaf Extract

Personality identification
The leaves are primarily shrunken, curled and also broken, as well as the intact ones are oblong after damp and flattened, 4-11cm long and also 2.5-9cm large. The apex is long or intense, the base is rounded or generally wedge-shaped, and also the edge is crenellated. Purple on both sides or green on the upper surface area, purple on the reduced surface, sparsely grayish-white hairs, with many pit-like adenoid scales on the reduced surface. The petiole is 2-7cm long, purple or purple-green. Slim and crisp. Those with twigs, the diameter of the branches is 2-5mm, purple-green, with pith in the middle of the area. The air is great smelling as well as the taste is somewhat zesty.
Physical and chemical identification
Take 0.7 g of coarse powder, put it in a 500ml round-bottomed flask, include 250ml of water, mix well, link the unpredictable oil measuring tool, include water from the upper end of the determining tool to the mark, and overflow right into the flask, include petroleum ether (60 ~ 90 ℃) 1.5 ml, attach a reflux condenser, heat it to boiling, keep it somewhat steaming for 2h, let it amazing, and also take the oil ether layer as the examination remedy. On top of that, 0.7 g of perilla leaf recommendation medicinal material was taken, and also the referral medicinal product option was prepared by the exact same method. Pipette 10 μl of each of the above 2 remedies, point them on the very same silica gel G thin-layer plate, develop with oil ether (60-90 ° C)- ethyl acetate (19:1), spray with dinitrophenylhydrazine examination solution, and also area. In the chromatogram of the test substance, there are places of the same color at the settings representing the recommendation medicinal products.
UV spectral identification
Take 1 g of sample rugged powder (20-40 mesh), 4 parts, put them in 50-ml iodine measuring flasks, add oil ether (60-90 ℃), chloroform, absolute ethanol as well as 20 ml of distilled water to each, soak at space temperature level for 2 hrs, shake, After purification, the filtrate was properly thinned down with the equivalent solvent, and its ultraviolet spectrum was gauged on a Shimadzu UV-3000 ultraviolet spectrophotometer. Examination conditions: wavelength array 190 ~ 400nm, absorbance range 0 ~ 3A, slit 1nm, scanning speed 200nm/min, range development 20nm/cm. Outcomes The λmaxPet of perilla leaves was 221.5, 233.0, (270.0 sh), (286.0) nm, the λmaxCHCl3 was 247.0, (273.0 ), 286.3(sh), 326.3(sh), 374.3(sh) nm, and also the λmaxEtOH was (206.5 ), (210.0 ), 234.8 (sh), 286.0, 329.3 nm, λmaxH2O is (211.0 ), (270.5 sh), (277.0 ), (285.0 ), 328.0 nm.

About Products:
If you need Perilla Ocymoides Leaf Extract, a cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
Our company, as an experienced Perilla Ocymoides Leaf Extract manufacturer and supplier, ZSpharmac will provide Perilla Ocymoides Leaf Extract raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, and customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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