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Papain Beazyme CAS 9001-73-4

Molecular Formula: C9H14N4O3

Formula Weight: 226.23246

ZSpharmac: Papain Beazyme Supplement

Product Name: Papain Beazyme
CAS No: 9001-73-4
Purity: 99%

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Basic Info

Product Name:Papain Beazyme
Other Names:Papain
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Almost White lyophilized Powder
EINECS No.:232-627-2
Provide:Papain Beazyme MSDS;
Papain Beazyme COA

What is Papain Beazyme?

Papain Beazyme is a sulfhydryl-containing (-SH) endopeptidase with protease as well as esterase activities, wide uniqueness, and strong hydrolysis capability for animal as well as plant proteins, polypeptides, esters, amides, etc, At the same time, it also has an artificial function, which can synthesize healthy protein hydrolyzate into protein-like. The most suitable pH worth is 5.7 (usually 3 ~ 9.5), and also it likewise works when it is neutral or somewhat acidic, the isoelectric point is 18.75; the most ideal temperature level is 55 ~ 60 ℃ (typically 10 ~ 85 ℃), warm resistance It is solid as well as will not be entirely suspended at 90 ° C; it is prevented by oxidants and activated by reducing materials. The enzyme that is dried out without clarification is the unrefined enzyme.

Papain Beazyme Properties

Fp 29 °C
storage temp. 2-8°C
solubility H2O: soluble1.2mg/mL
form lyophilized powder
color almost white
Water Solubility Soluble in water, insoluble in most organic solvents.


Papain Beazyme Uses

  1. Papain Beazyme is suitable for the hydrolysis of aquatic products such as fish and shellfish.
  2. Papain Beazyme is primarily used for beer chilly resistance (hydrolyzed healthy protein in beer to prevent turbidity after refrigeration), meat conditioning (hydrolyzed muscle mass healthy protein as well as collagen to tenderize meat), preparation of cereal pre-cooking, hydrolyzed protein Manufacturing. It is much more extensively made use of in beer cool resistance as well as meat conditioning than other proteases. The dose is generally 1 to 4 mg/kg.
  3. Papain Beazyme is commonly made use of for meat tenderization and also as a making clear representative for beer. my country stipulates that it can be utilized for biscuits, meat and fowl items hydrolysis as well as animal as well as vegetable healthy protein, as well as it can be utilized in small amounts according to manufacturing demands.
  4. Papain Beazyme is used in pharmaceutical, food industry and also aesthetic additives.
  5. Papain Beazyme is a vital cysteine protease utilized in peptide synthesis. Fab fragments utilized in the manufacturing of antibodies; likewise made use of in cell lysis as a result of very little damage to certain tissues. Cleavage of amino acids (leucine, or glycine).
  6. Papain Beazyme can activate plasminogen to plasmin. It acts only on necrotic cells, liquifying fibrin, embolism and also lethal product within the lesion. Cleanses the injury surface, advertises new granulation, and also promotes pus drain. Accelerates injury recovery. Papain is generally utilized to treat edema, swelling, and also to deworm (nematode) diseases. Nevertheless, there was mild dermatitis as well as neighborhood blood loss and also pain after taking the medication. Duplicated usage can cause allergies. It ought to be utilized with caution in clients with serious liver and kidney condition, and also ought to not be made use of in clients with blood coagulation deficiency and systemic infection, and also ought to not be utilized in combination with anticoagulants.

Application of Papain Beazyme in Food

With the improvement of people’s economic conditions, the pursuit of quality of life has gradually become higher. People are no longer limited to solving basic food and clothing, but pursue the taste and appearance of food. Papain Beazyme plays an important role in the meat tenderizer. If no meat tenderizer is added, the meat will often become rough and hard after being heated and cooked, but adding an appropriate amount of meat tenderizer will lock the moisture in the meat, making the food soft and tender.

Cysteinyl protease in Papain Beazyme can rapidly degrade myofibrils and connective tissue. Even if processed at a temperature of about 90°C, it can still maintain its own activity, preserve the nutrition of meat, and help the body digest and absorb. Especially for beef with more tendons, the meat tenderizer powder containing Papain Beazyme in an appropriate concentration can make it soft and easy to chew and increase the taste of beef.

For fish meat, those small and low-value small trash fish are often not popular, so we can use the hydrolysis properties of Papain Beazyme to produce a higher concentration of hydrolyzed protein, and dissolve the whole small fish into protein concentrate. It can be made into canned small fish or minced fish sausage that is convenient to carry and eat. In addition, Papain Beazyme can also extend the shelf life of food, prevent animal meat and bones from spoiling and spoiling, and is often used as an important medium for slaughterhouses to recover ground meat components in bones.

During the long-term storage of beer, due to the action of the macromolecular protein in it, a turbid mist is formed, which causes a large amount of precipitation in the originally unstable colloidal solution, which affects subsequent sales and storage. To change this situation, it is necessary to add an appropriate concentration of Papain Beazyme to the fermented alcohol to improve the stability of the beer, hydrolyze the macromolecular protein in the beer, so as to avoid turbidity and affect the color, and also prolong the preservation of the beer. Expect.

More importantly, Papain Beazyme can change the content of free amino acids in beer, increase the amino acid content in beer, so that beer can keep foaming, if it is properly added and fully stirred during beer filling, it can improve beer. taste and increase the nutrients in beer.

Pastries are often made from flour and are low in protein. The gluten of flour is not high, so when using high-gluten flour to make pastries, it is necessary to increase the content of vegetable oil or egg. If you want to make Western-style pastries with a soft taste, you must reduce the gluten of the flour to improve the looseness of the pastry. Effect. The use of papain in flour can hydrolyze the protein in flour, reduce flour gluten, produce biscuits and cakes with good flavor and soft taste, and enhance their economic value.

The content of essential amino acids in soybean protein is appropriate and the nutritional value is high, but precipitation and viscosity often occur in the process of production and use. The use of papain can change the physical and chemical properties of soybean protein. The free amino acids in Papain Beazyme interact with the protein, which can make the soybean protein gel. Putting the concentrated soybean protein into meat and dairy processing can improve the nutritional structure of the food and improve the economic benefits.

Papain Beazyme has been widely used in the food field, and has also played a huge role in meat, beer, pastry and other industries. The use of papain can produce more safe, green and nutritious food, which can affect and improve people’s diet structure and quality of life invisibly, and its own dietary and health care effects are more conducive to people’s health. Therefore, the market prospect of papain is immeasurable.

Papain Beazyme Production Method

Dried papaya emulsion diatomaceous earth; sand; 0.04mol·L-1 cysteine→extraction, filter crude extract
NaOH;Ph9→Remove Ph9 insoluble supernatant
sedimentation, centrifugation
Crude extract (NH4)2SO{4→precipitation; centrifugal precipitation 0.02mol·L-1 cysteine; Ph7→dissolving solution
NaCl (solid)→precipitation; centrifugal precipitation 0.02mol·L-1 cysteine; Ph6.5→dissolving solution
Freezing, centrifuging, recrystallization solution 40→freezing; centrifugal crystallization ^H2O; NaCl→recrystallization finished product

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Papain Beazyme Quotation