Zhishang Chemical

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Zhishang Chemical

Palmitoyl Tripeptide-1 CAS 147732-56-7

Molecular Formula: C30H54N6O5

Formula Weight: 578.79

ZSpharmac: Palmitoyl Tripeptide-1 Supplement

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Product Name: Palmitoyl Tripeptide-1
CAS No: 147732-56-7
Purity: 99%

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Basic Info

Product Name:Palmitoyl Tripeptide-1
Other Names:Pal-Tripeptide-1、L-Lysine、Palmitoyl Tripeptide-1Pal-AHK
CAS:147732-56-7
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Colorless Viscous Liquid
EINECS No.:0
Storage:Under Inert Gas (Nitrogen or Argon) at 2–8 °C
Provide:Palmitoyl Tripeptide-1 MSDS;
Palmitoyl Tripeptide-1 COA

What is Palmitoyl Tripeptide-1?

The GHK element of Palmitoyl Tripeptide-1 methods fibroblasts right into assuming that elastin, an usual skin healthy protein, has been harmed. This induces fibroblasts to expand and also multiply to make sure that they can regenerate what they think is the shed elastin in the skin In aged animals, fibroblasts have a tendency to come to be inactive and also go dormant. Pet model research studies reveal that GHK can reactivate fibroblasts to help get over several of the common effects old on the skin.

The Buddy component of Palmitoyl Tripeptide-1 is a vector. By connecting this fatty ester to a peptide series, higher skin as well as cell permeation can be accomplished in pet versions. In other words
That stated, Friend’s job is to assist GHK get to where it’s most beneficial– within cells deep within the skin.

Polypeptide describes 2 or even more amino acids linked together and also is the building block of a healthy protein. Peptides fall under three wide categories: signal peptides, service provider peptides, as well as peptides that prevent neural signaling. Signal peptides serve as carriers for cells, which set off the synthesis of collagen, which raises skin firmness.

According to Nancy Samolitis, MD, FAAD: “Intact, unfragmented proteins such as collagen can not be taken in straight with the leading layer of the skin, so these smaller fragments can go deep at the cellular level … Peptides are primarily fragmented. As a result, When they are utilized in skin treatment, the objective is for these fragments of collagen to stimulate collagen growth.”

Palmitoyl tripeptide-1 is a little 3 amino acid signal peptide with the amino acid sequence of glycine-histidine-lysine (GHK). GHK connects to palmitic acid, a fat, to enhance its skin penetration and oil solubility. Using palmitoyl tripeptide-1 directly to the skin stimulates cells to create more, renewed collagen. It takes a minimum of 1 month or even more to begin seeing noticeable changes in brand-new collagen.

Structural Characteristics of Palmitoyl Tripeptide-1

Palmitoyl tripeptide-1 is a small 3 amino acid signal peptide with the amino acid series of glycine-histidine-lysine (GHK). GHK links to palmitic acid, a fatty acid, to boost its skin penetration and additionally oil solubility. Using palmitoyl tripeptide-1 directly to the skin improves cells to generate more, restored collagen. It takes at least 1 month or even extra to begin seeing visible modifications in brand-new collagen.

Application of Palmitoyl Tripeptide-1 in Cosmetics

Companies skin and additionally improves collagen manufacturing: As we age, collagen in the skin breaks down into peptides, these Palmitoyl Tripeptide-1 send signals to skin cells, telling them to make even a lot more collagen to make up for shed collagen healthy and balanced protein.

Topical monitoring of Palmitoyl Tripeptide-1 raises this signaling, which boosts the manufacturing of brand-new collagen. Minimizes the appearance of excellent lines: By promoting collagen production, Palmitoyl Tripeptide-1 help make skin appear plumper and also younger.

Strengthens the skin barrier: Peptides improve cellular job and likewise repair the skin’s natural obstacle feature to preserve dampness as well as additionally secure the body from foreign bodies. Lock in dampness: Collagen manufacturing declines with age, as well as collagen degrees in the skin drop over time. Collagen aids the skin preserve dampness, so the loss of collagen can likewise trigger dehydration of the skin.

While Palmitoyl Tripeptide-1 helps enhance collagen production, it likewise advertises hydration in the skin. Has Anti-Inflammatory High qualities: The antioxidants in Palmitoyl Tripeptide-1 support soothe and additionally eliminate the skin, decreasing swelling. Smooths complexion: With increased collagen production, skin will absolutely likewise end up being clearer and also a lot more likewise.

 

Palmitoyl Tripeptide-1 Mechanism of Action

Palmitoyl tripeptide-1 has effects on the synthesis of collagen, fibronectin and also hyaluronic acid in human skin fibroblasts, as well as can be utilized in the prep work of anti-aging cosmetics.

Palmitoyl Tripeptide-1 is an impressive peptide that has actually remained in use given that 1973. It’s an excellent anti-oxidant that assists prevent Alzheimer’s as well as other age-related psychological problems, assists new members vessels grow in harmed areas (assists recover), aids nerves fix themselves as well as It actually help in the growth of brand-new nerves, improves the activity of genes that help with recovery, while subduing genes that help trigger cancer, switching on recovery genetics that are silenced with age, as well as aiding skin expand as well as revitalize.

Palmitoyl Tripeptide-1 is a peptide that presumably describes the destruction of the skin matrix. When fibroblasts, the cells that generate the skin matrix, choose higher-range GHKs, they form various other skin matrices, presuming they are undoubtedly quickly involved. Pal-GHK is a refined version of GHK, since it penetrates the skin better, so it is likely to stimulate the replenishment of the skin matrix to complete topical desires. Creases, aging, small lyrics are visibly reduced, and skin reasons are much more undestroyable as well as smoother.

Palmitoyl Tripeptide-1 is meant to in fact regrow lost hair, comparable to 5% minoxidil (yet differently). It also improves the growth of skin collagen (making you look more youthful), greatly improves injury recovery, helps grow new blood vessels in damaged areas of the body, aids in nerve regeneration, and also reactivates silent genes involved in the recovery process.

 

Palmitoyl Tripeptide-1 Clinical Trial

Applying palmitoyl tripeptide-1 directly to the skin tells the cells to make more collagen, which stimulates new collagen production. It will take at least a month or more to start seeing visible changes in the new collagen, with maximum results seen after 3 to 4 months. Erin Gilbert, MD, FAAD, and board-certified dermatologist and neuroscientist continues: “Peptides can be included in serums, moisturizers, and masks,” explains Gilbert. “They’re also included in some topical serums used after microneedling or superficial laser surgery to increase penetration of the peptides and help the skin recover from surgery.

A CIR panel has actually wrapped up that peptides, such as palmitoyl tripeptide-1, are secure in cosmetic and self-care products. The Environmental Working Team (EWG) presently prices palmitoyl tripeptide-1 as “1” or “low danger”. Generally, peptides, such as palmitoyl tripeptide-1, mimic substances currently existing in the body, and also studies of the peptide’s result on the skin have actually been revealed to be limited to no skin irritation. There are no released studies documenting any type of well-known poisoning in regards to peptide-induced poisoning.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

OUR MISSION
Help China Chemicals to benefit the happiness of human life
OUR VISSION
Become the most trusted chemical supplier in the world
OUR BUSINESS PHILOSOPHY
Striver – oriented, enrich employees, customer first, deep service, seek development
OUR VALUES
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.

Service

Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.

 

After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.

FAQ

Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.

 

HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?

You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.

Shipping

1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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