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Palmitoyl Pentapeptide-4 CAS 214047-00-4

Molecular Formula: C39H75N7O10

Formula Weight: 802.05

ZSpharmac: Palmitoyl Pentapeptide-4 Supplier

Product Name: Palmitoyl Pentapeptide-4
CAS No: 214047-00-4
Purity: 99%

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Basic Info

Product Name:Palmitoyl Pentapeptide-4
Other Names:Palmitoyl Pentapeptide
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Colorless Liquid
EINECS No.:606-757-9
Storage:2-8°C(Protect From Light)
Provide:Palmitoyl Pentapeptide-4 MSDS;
Palmitoyl Pentapeptide-4 COA

What is Palmitoyl Pentapeptide-4?

Pentapeptide is a polypeptide composed of five amino acids connected by peptide bonds. This short peptide is widely used in chemistry and biochemistry, especially in cosmetics and personal care products.

The specific mechanism of action of pentapeptide in cosmetics may involve the activation of specific cell signaling pathways, such as MAPK, Smad or PI3K/Akt pathways, thereby promoting collagen synthesis and skin regeneration. Their use needs to take into account factors such as concentration, formula compatibility and permeability to ensure optimal skin absorption and effect.

Palmitoyl Pentapeptide-4 Property

Boiling point 1120.1±65.0 °C(Predicted)
density 1.147
storage temp. 2-8°C(protect from light)


Palmitoyl Pentapeptide-4 Uses

1. Cosmetics and Skin Care
Anti-aging: Palmitoyl Pentapeptide-4 stimulates the production of collagen and elastin, two proteins that are essential for maintaining the elasticity and firmness of the skin. Therefore, pentapeptides are often used in anti-aging skin care products to help reduce wrinkles and improve skin density and elasticity.
Moisturizing: Palmitoyl Pentapeptide-4 promotes the production of hyaluronic acid and improves the skin’s ability to retain water, thereby improving dry and rough skin conditions.
Wound healing: Certain pentapeptides may promote skin repair and regeneration, helping to speed up the wound healing process.

2. Drug Development
Therapeutic agents: Palmitoyl Pentapeptide-4 can be used as part of a drug molecule to treat specific diseases, such as promoting bone repair or treating muscle diseases.
Drug delivery systems: The structural properties of pentapeptides make them good candidates for constructing drug carriers, which can help drugs penetrate biological membranes more effectively and reach target tissues.

3. Biomedical Research
Research Tools: In basic research, Palmitoyl Pentapeptide-4 can be used as a probe to study protein-protein interactions, signal transduction pathways, and gene expression regulation mechanisms.

4. Food Science
Functional Foods: Some Palmitoyl Pentapeptide-4s have biological activities, such as antioxidant or anti-inflammatory effects, and can be used as food additives to increase the nutritional value and health benefits of foods.

5. Sports and Sports Nutrition
Muscle Recovery: Pentapeptides may help muscle recovery after exercise, promote muscle protein synthesis, and reduce muscle damage.

6. Biotechnology
Biosensors: Palmitoyl Pentapeptide-4 can be designed as a recognition element for specific molecules and used to build biosensors to monitor specific compounds in the environment or biomarkers in the body.

7. Environmental Science
Pollutant Degradation: Some specific Palmitoyl Pentapeptide-4s may participate in or catalyze the biodegradation process of certain environmental pollutants.

8. Agriculture
Plant growth regulation: In agriculture, specific Palmitoyl Pentapeptide-4 may act as a plant growth regulator, affecting the plant’s growth cycle and ability to respond to environmental stress.

9. Chemical synthesis and materials science
Novel materials: The self-assembly properties of Palmitoyl Pentapeptide-4 can be used to develop new biocompatible materials, such as scaffold materials for tissue engineering.

Palmitoyl Pentapeptide-4 in Cosmetics

1. Stimulate collagen production
Anti-aging effects: Pentapeptides, especially Palmitoyl Pentapeptide-4 (also known as Matrixyl), can stimulate skin fibroblasts to produce more collagen and elastin. As we age, the skin’s natural production of collagen decreases, leading to sagging skin and wrinkle formation. Pentapeptides help fill fine lines and wrinkles by promoting collagen production, restoring skin firmness and elasticity.

2. Promote skin repair
Wound healing: Certain Palmitoyl Pentapeptide-4s have properties that promote skin wound healing. They can speed up the repair process of damaged skin and reduce scar formation.
Skin barrier function: Pentapeptides help strengthen the skin’s barrier function, prevent water loss, and protect the skin from environmental factors.

3. Lighten pigmentation
Whitening effect: Some Palmitoyl Pentapeptide-4 ingredients can regulate the production of melanin, which helps to lighten spots and brighten the skin tone, achieving a whitening effect.

4. Improve skin moisturizing
Moisturizing effect: Palmitoyl Pentapeptide-4 can enhance the skin’s own moisturizing ability, increase the production of hyaluronic acid, keep the skin moisturized, and reduce skin problems caused by dryness.

5. Antioxidant and anti-inflammatory
Skin protection Palmitoyl Pentapeptide-4 also has certain antioxidant and anti-inflammatory effects, which can reduce the damage of free radicals to the skin, reduce inflammatory reactions, and protect the skin from oxidative stress.

6. Improve blood circulation
Reduce red blood streaks: Palmitoyl Pentapeptide-4 can reduce capillary dilation, help reduce the appearance of facial red blood streaks, improve skin microcirculation, and make the skin tone more even.

7. Nerve conduction inhibition
Smooth expression lines: Pentapeptide ingredients with nerve conduction inhibition function, such as acetyl hexapeptide-3, can relax expression lines caused by nervous tension and reduce the depth and frequency of dynamic lines.


National Center for Biotechnology Information. PubChem Compound Summary for CID 9897237, Palmitoyl Pentapeptide-4. https://pubchem.ncbi.nlm.nih.gov/compound/Palmitoyl-Pentapeptide-4. Accessed July 10, 2024.

As a company specializing in the production and supply of Palmitoyl Pentapeptide-4 raw materials, we are committed to providing customers with high-quality products and preferential prices. We have rich experience and technology to ensure the quality and stable supply of our products. No matter where you are, we can provide you with the required Palmitoyl Pentapeptide-4 raw materials to support your production and research and development.

We always adhere to the principle of honest management, strictly control product quality, and serve every customer with a customer-first attitude. Over the years, we have established good cooperative relations with domestic and foreign customers and won their trust and praise.

If you have any needs or are interested in our products, please contact our service staff directly, and we will wholeheartedly provide you with the best service and products. Looking forward to cooperating with you and developing together!

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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