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Palmitoleic Acid CAS 373-49-9

Molecular Formula: C16H30O2

Formula Weight: 254.41

ZSpharmac: Palmitoleic Acid Cosmetic Raw Material Suppliers

Product Name: Palmitoleic Acid
CAS No: 373-49-9
Purity: 99%

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Basic Info

Product Name:Palmitoleic Acid
Other Names:9-Hexadecenoic Acid
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Clear Liquid
EINECS No.:206-765-9
Provide:Palmitoleic Acid MSDS;
Palmitoleic Acid COA

What is Palmitoleic Acid?

Palmitoleic acid, also known as palmitoleic acid, is a monounsaturated fatty acid with a chemical formula of C16H30O2 and a molecular weight of 254.42 g/mol. It belongs to the ω-7 (n-7) series of fatty acids because it contains a double bond at the 7th carbon atom. Palmitoleic acid is an important bioactive molecule found in a variety of animal and vegetable oils. Although its content is relatively small, its unique chemical structure gives it a series of beneficial physiological properties.

The structural characteristics of palmitoleic acid are that it is a chain fatty acid containing 16 carbon atoms, with a carbon-carbon double bond located at the Δ9 position (i.e., between the 9th and 10th carbon atoms from the carboxyl end). This structure makes it a liquid oily substance, usually a colorless or light yellow transparent liquid at room temperature. Palmitoleic acid has good antioxidant properties and low-temperature stability, which makes it of special value in food, cosmetics and certain industrial applications.

Palmitoleic Acid Property

Melting point 0.5 °C (lit.)
Boiling point 162 °C/0.6 mmHg (lit.)
density 0.895 g/mL at 20 °C (lit.)
refractive index 1.457-1.459
Fp 62 °C
storage temp. -20°C
solubility Chloroform, Methanol (Slightly)
form Liquid
color Clear


Application of Palmitoleic Acid

1. Cosmetics and personal care products
Skin care: Palmitoleic acid is often added to skin care products such as creams, lotions, and essences due to its excellent moisturizing properties and skin permeability. It can help maintain the moisture balance of the skin, improve skin elasticity and softness, and reduce the appearance of fine lines and wrinkles.
Hair care: In hair care products, palmitoleic acid can moisturize hair, strengthen hair quality, reduce split ends, and improve scalp health.

2. Medicine and nutritional supplements
Dietary supplements: As a ω-7 series fatty acid, palmitoleic acid is considered to be beneficial to cardiovascular health and helps regulate blood lipid levels. Therefore, it is used as a nutritional supplement in health products to help improve metabolic syndrome and prevent cardiovascular disease.
Drug formulations: In the field of medicine, palmitoleic acid and its derivatives are used to prepare drugs, such as as a drug carrier to improve the solubility and bioavailability of drugs, or directly as a drug ingredient for the treatment of specific diseases.

3. Food Industry
Food additives: Palmitoleic Acid can be used as an emulsifier and stabilizer to improve the taste of food and extend the shelf life, especially in dairy products, baked goods and margarine.
Nutrient fortification: In infant formula and special medical purpose foods, palmitoleic acid is used as a nutritional fortifier to provide essential fatty acids and support healthy growth.

4. Industrial applications
Plastics and polymers: As a chemical intermediate, palmitoleic acid can be used to produce polymer materials such as polyester and polyurethane to improve the flexibility and weather resistance of materials.
Surfactants and emulsifiers: In industrial cleaners, coatings, and inks, palmitoleic acid and its esters are used as efficient surfactants to promote emulsification, dispersion, and improve product performance.
Lubricants and oils: The esterification products of palmitoleic acid can be used as advanced lubricants and metalworking oils, with good lubricity, antioxidant properties and low-temperature fluidity.

5. Agriculture and biotechnology
Biopesticides: Palmitoleic Acid derivatives are used as bio-source pesticides with environmentally friendly properties to control pests and diseases.
Biofuel: In the field of biofuel, palmitoleic acid can be used as a raw material to convert into biodiesel, providing a new option for renewable energy.

6. Scientific research and new material development
Biomedical materials: Palmitoleic acid is used as a functional component in the development of biomedical materials such as tissue engineering and drug delivery systems to improve the biocompatibility and functionality of materials.
Nanotechnology: As a surface modifier, palmitoleic acid can improve the dispersion and stability of particles in the preparation of nanomaterials, and promote the application of materials in biomedicine, environmental protection and other fields.

Palmitoleic Acid in Cosmetics

1. Supplementation of Natural Moisturizing Factor (NMF)
Palmitoleic Acid, as one of the naturally occurring ingredients in the skin, can replenish the skin’s natural moisturizing factor and help maintain the skin’s moisture balance. It can penetrate the skin’s surface, deeply nourish, reduce transepidermal water loss, thereby improving dry and rough skin conditions and enhancing the skin’s barrier function.

2. Promote skin cell regeneration
The characteristics of its ω-7 fatty acids give palmitoleic acid the ability to promote skin cell renewal, help accelerate wound healing, reduce inflammatory responses, fight the formation of fine lines and wrinkles during aging, and enhance the skin’s overall radiance and elasticity. It is often used in anti-aging products.

3. Enhance formula stability
In cosmetic formulas, Palmitoleic Acid, as an emulsifier and stabilizer, helps stabilize the water-oil system and prevents product stratification or deterioration. This is particularly important for the preparation of multi-phase cosmetics such as emulsions and creams, ensuring the uniformity, fineness and long-lasting stability of the product.

4. Improve skin feel
Due to its good oil properties, palmitoleic acid can give cosmetics a smooth texture, making the product easy to apply, fast absorption, and no greasy feeling, which improves the user experience. This is particularly valuable for skin care products that pursue lightness and breathability.

5. Mildness and safety
Compared with some ionic surfactants, the non-ionic properties of Palmitoleic Acid make it less irritating to the skin and suitable for a wide range of people, including sensitive skin. Its low risk of acne also makes it an ideal choice for cleansing products and skin care formulations.

6. Antioxidant properties
Palmitoleic Acid also shows certain antioxidant properties, which can help resist free radical damage, protect the skin from environmental stress and UV damage, and further delay the skin aging process.


National Center for Biotechnology Information. PubChem Compound Summary for CID 445638, Palmitoleic Acid. https://pubchem.ncbi.nlm.nih.gov/compound/Palmitoleic-Acid. Accessed June 28, 2024.

As a company specializing in the production and supply of Palmitoleic Acid raw materials, we are committed to providing customers with high-quality products and preferential prices. We have rich experience and technology to ensure the quality and stable supply of our products. No matter where you are, we can provide you with the required Palmitoleic Acid raw materials to support your production and research and development.

We always adhere to the principle of honest management, strictly control product quality, and serve every customer with a customer-first attitude. Over the years, we have established good cooperative relations with domestic and foreign customers and won their trust and praise.

If you have any needs or are interested in our products, please contact our service staff directly, and we will wholeheartedly provide you with the best service and products. Looking forward to cooperating with you and developing together!

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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